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| 1 | Comparison of in-hospital outcomes between octogenarians and nonagenarians undergoing transcatheter aortic valve replacement: a propensity matched analysis显示文摘BackgroundAortic 阀门狭窄(作为) 在在 80 年上面的老病人是很普通的。在如此的病人的 Transcatheter 大动脉的阀门代替(TAVR ) 逐渐地正在被执行。寻求在与严重 AS.MethodThe 学习人口经历 TAVR 的九十至九十九岁的人估计死亡的 octogenarians 和九十至九十九岁的人和预言者之间的在里面医院结果差别的这研究从国家住院病人样品(网络信息服务) 被导出 2012-2014 使用 ICD-9 厘米过程为 TAVR 编码 35.05 和 35.06 的年。低于 80 岁的住院被排除。在执行倾向 20 以后匹配(1:2 ) ,在里面医院结果在匹配的队被比较。然后, multivariate 模型被开发在 nonagenarians.ResultsThere 分析在里面医院死亡的预言者是 11,630 个住院在八十至八十九岁并且在九十至九十九岁的人组的 5815 个住院。在里面医院死亡的主要结果(6% 对 4.1% , P 0.001 ) 在与 octogenarians 相比的九十至九十九岁的人是更高的。第二等的结果包括击(3.4%对2.8%, P 0.001 ),肾的失败(18.9%对17.3%, P 0.001 ),输血(35%对32.6%, P 0.001 ),脉管的复杂并发症(4.5%对3.5%, P 0.001 ),并且心律调整器培植(27.8%对24.8%, P 0.001 )在九十至九十九岁的人是更高的。在他们停留的长度没有差别。中部的费用(70,374 $ 对 65,381 $ , P 0.001 ) 与 nonagenarian.ConclusionsAlthough 在里面医院是稍微更高的死亡在九十至九十九岁的人是稍微更高的,它是可接受的。在死亡的这差别被更高的复杂并发症部分至少在九十至九十九岁的人解释。努力应该被成为能进一步在在这些组之间的在里面医院死亡缩小差别的复杂并发症到减少。 | Rajkumar Doshi Vaibhav Patel Priyank Shah | 2018 | Journal of Geriatric Cardiology2018,15,2: | 2 |
| 2 | Layered inorganic nanocomposites: A promising carrier for 5-fluorouracil (5-FU)显示文摘 | Bhavesh D. Kevadiya Tapan A. Patel Devendrasinh D. Jhala Rahul P. Thumbar Harshad Brahmbhatt Maharshi P. Pandya Shalini Rajkumar Prasant K. Jena Ghanshyam V. Joshi Pankaj K. Gadhia C.B. Tripathi Hari C. Bajaj | 2012 | European Journal of Pharmaceutics and Biopharmaceutics2012,,: | 2 |
| 3 | Antibacterial Behaviour of Quaternized Poly(vinyl chloride)-g-Poly(4-vinyl pyridine) Graft Copolymers显示文摘Amphiphilic graft copolymers consisting of poly(vinyl chloride)(PVC) main chains and poly(4-vinyl pyridine)(P4VP) side chains were synthesized via atom transfer radical polymerization(ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4 VP graft copolymers was confirmed by Fourier transform infrared spectroscopy(FTIR) and proton nuclear magnetic resonance(1H-NMR). Transmission electron microscope(TEM) and small angle X-ray scattering(SAXS) analysis showed that PVC-g-P4 VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-gP4 VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli(E. coli), Staphylococcus aureus(S. aureus), Bacillus cereus(B. cereus), and Pseudomonas aeruginosa(P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP(46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell. | Madhumita Patel Rajkumar Patel Won Seok Chi Jong Hak Kim Jung-Suk Sung | 2015 | Chinese Journal of Polymer Science2015,33,2: | 2 |
| 4 | Activity of superoxide dismutase isoenzymes inlens epithelial cells derived from different types of age-relatedcataract 显示文摘 | Rajkumar S Praveen MR Gajjar D Vasavada AR Alapure B Patel D | | J Cataract Refract Surg0,34,3: | 1 |
| 5 | Layered inorganic nanocomposites: A promising carrier for 5-fluorouracil (5-FU)显示文摘 | Bhavesh D. Kevadiya Tapan A. Patel Devendrasinh D. Jhala Rahul P. Thumbar Harshad Brahmbhatt Maharshi P. Pandya Shalini Rajkumar Prasant K. Jena Ghanshyam V. Joshi Pankaj K. Gadhia C.B. Tripathi Hari C. Bajaj | 2012 | European Journal of Pharmaceutics and Biopharmaceutics2012,,1: | 1 |
| 6 | Silver nanoparticles immobilized on thinfilm composite polyamide membrane: characterization, nanofiltration, antifouling properties显示文摘 | LEE Seung Yun KIM Hee Jin PATEL Rajkumar | 2007 | Polymers for Advanced Technologies2007,18,: | 1 |
| 7 | Silver nanoparticles immobilized on thin film composite polyamide membrane: characterization, nanofiltration, antifouling properties显示文摘 | Seung Ytm Lee Hee Jin Kim Rajkumar Patel | 2007 | Polymers for Advanced Technologies2007,18,7: | 1 |
| 8 | Recent development in upconversion nanoparticles and their application in optogenetics:A review显示文摘Ion channels present in the plasma membrane are responsible for integration and propagation of electric signals,which transmit information in nerve cells.Malfunction of these ion channels leads to many neurological diseases.Recently,optogenetic technology has gained a lot of attention for the manipulation of neuronal circuits.Optogenetics is a neuromodulation approach that has been developed to control neuronal functions and activities using light.The lanthanide-doped upconversion nanoparticles(UCNPs)absorb low energy photons in near-infrared(NIR) window and emit high energy photons in the visible spectrum region via nonlinear processes.In the last few decades,UCNPs have gained great attention in various bio-medical applications such as bio-imaging,drug delivery and optogenetics.The near-infrared illumination is considered more suitable for optogenetics application,due to its lower degree of light attenuation and higher tissue penetration compared to visible light.Therefore,UCNPs have been considered as the new promising candidates for optogenetics applications.Upconversion nanoparticlemediated optogenetic systems provide a great opportunity to manipulate the ion channel in deep tissue.Herein,we summarize the upconversion photoluminescence in lanthanide doped nanomaterials and its mechanisms and several approaches adopted to tune emission color or enhance upconversion efficiency.Recent advances of lanthanide-doped UCNPs design strategy and their mechanism are reviewed.Then,we discuss the neural circuitry modulation using upconversion nanoparticles mediated optogenetics.Moreover,the future perspectives towards optogenetics are also included. | Madhumita Patel Maninder Meenu Jitender Kumar Pandey Pawan Kumar Rajkumar Patel | 2022 | Journal of Rare Earths2022,40,6: | 1 |
| 9 | Burden of atrial fibrillation in patients with rheumatic diseases显示文摘BACKGROUND Studies have suggested that atrial fibrillation(AF)in patients with rheumatic diseases(RD)may be due to inflammation.determine morbidity and mortality associated with AF in hospitalized patients with RD.METHODS The National inpatient sample database from October 2015 to December 2017 was analyzed to identify hospitalized patients with RD with and without AF.A subgroup analysis was performed comparing outcomes of AF among different RD.RESULTS The prevalence of AF was 23.9%among all patients with RD(n=3949203).Among the RD subgroup,the prevalence of AF was highest in polymyalgia rheumatica(33.2%),gout(30.2%),and pseudogout(27.1%).After adjusting for comorbidities,the odds of having AF were increased with gout(1.25),vasculitis(1.19),polymyalgia rheumatica(1.15),dermatopolymyositis(1.14),psoriatic arthropathy(1.12),lupus(1.09),rheumatoid arthritis(1.05)and pseudogout(1.04).In contrast,enteropathic arthropathy(0.44),scleroderma(0.96),ankylosing spondylitis(0.96),and Sjorgen’s syndrome(0.94)had a decreased association of AF.The mortality,length of stay,and hospitalization costs were higher in patients with RD having AF vs without AF.Among the RD subgroup,the highest mortality was found with scleroderma(4.8%),followed by vasculitis(4%)and dermatopolymyositis(3.5%).CONCLUSION A highest association of AF was found with gout followed by vasculitis,and polymyalgia rheumatica when compared to other RD.Mortality was two-fold higher in patients with RD with AF. | Muhammad Zubair Khan Kirtenkumar Patel Krunalkumar A Patel Rajkumar Doshi Vraj Shah Devina Adalja Zainulabedin Waqar Sona Franklin Neelesh Gupta Muhammad Hamdan Gul Shruti Jesani Steven Kutalek Vincent Figueredo | 2021 | World Journal of Clinical Cases2021,9,14: | 0 |