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| 1 | 生态风险分析:Saimaa环斑海豹案例显示文摘生态风险分析是在给定条件下估计种群灭绝危险的一种方法。这种估计对于保护一个地区的生物是至关重要的。由于在给定的条件中既含有现实状况也包括一些假设条件,因而就有可能事先估计出可能的管理行为所带来的后果。然而在管理上使用模拟模型有一个问题,就是模型输出的结果取决于所获得信息的准确性。因此除非仔细分析不确定性对结果的影响,否则仅仅依靠模拟模型是有风险的。我们以芬兰东南部Saimaa湖区域内高度濒危的环斑海豹种群为例,报道了生态风险分析的案例研究。水位变化导致洞穴倒塌杀伤幼小海豹和捕猎是降低种群性能的主要因子。研究表明,虽然每个因子单独不会使种群灭绝危险增加到不能容许的水平,但两个因子结合在一起造成的后果恐怕是致命的。 | Esa Ranta Jan Lindstrm Hanna Kokko 汪业勖 | 1996 | 人类环境杂志1996，25，5： | 2 |
| 2 | Hypercalciuria in children with haemophilia suggests primary skeletal pathology显示文摘 | Ranta S Viljakainen H M?kipernaa A | 2011 | Br J Haematol2011，153，3： | 1 |
| 3 | Follicle-stimulating hormone receptors appear earlier in the primate fetal testis than in the ovary显示文摘 | Huhtaniemi IT Yamamoto M Ranta T | 1987 | J Clin Endocrinol Metab1987，65，6： | 1 |
| 4 | Impaired interferon production by leukocytes from patients with Bell palsy and lack of findings suggestive for a systemic viral involvement显示文摘 | Pitk?ranta A Hovi T Peltomaa M | 1997 | The American Journal of Otology1997，18，2： | 1 |
| 5 | Awareness and recall in outpatient anesthesia显示文摘 | Wennervirta J Ranta SO Hynynen M | 2002 | Anesth Analg2002，95，1： | 1 |
| 6 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 7 | Materal expectations and experiences of labour pain-options of 1091 Finnish partufients显示文摘 | Ranta P Spalding M Kangas S | 1995 | Acta Anaesthesiol Scand1995，39，1： | 1 |
| 8 | Application of artificial neural networks as an indicator of awareness with recall during general anaesthesia显示文摘 | Hynynen M Rasanen J | 2002 | J Clin Monit Comput2002，17，1： | 1 |
| 9 | Patients'conscious recollections from cardiac anesthesia 显示文摘 | RANTA S O HERRANEN P HYNYNEN M | 2002 | J Cardiothorac Vasc Anesth2002，16，2： | 1 |
| 10 | Folliclestimulating hormone receptors appear earlier in the primate fetal testis than in the ovary显示文摘 | Huhtaniemi IT Yamamoto M Ranta T | 1987 | J Clin Endocrinol Metab1987，65，6： | 1 |
| 11 | Awareness and recall in outpatient anesthesia显示文摘 | Wennervirta J Ranta SO Hynynen M | | 0，，01： | 1 |
| 12 | Maternal deaths in Finland : focus on placental abruption显示文摘 | TikkanenM Gissler M Metsa'ranta M | 2009 | Acta Obstet Gynecol Scand2009，88，10： | 1 |
| 13 | Recall of awareness during cardiac anaesthesia: influence of feedback information to the anaesthesiologist 显示文摘 | Ranta S Jussila J Hynynen M | 1996 | Acta Anaesthesiol Scand1996，40，5： | 1 |
| 14 | Associations between peer victimization,self-reported depression and social phobia among adolescents:The role of comorbidity显示文摘 | Ranta K Kaltiala-Heino R Pelkonen M | 2009 | Journal of Adolescence2009，32，： | 1 |
| 15 | Lead poisoning and recurrent abdominal pain显示文摘 | Shiri R Ansari M Ranta M | | 0，，03： | 1 |
| 16 | Synchronous dynamics and rates of extinction in spatially structured populations显示文摘 | Heino M Kaitala V Ranta E | | 0，，： | 1 |
| 17 | Patients consciousre collections from cardiac anesthesia显示文摘 | Ranta SO Herranen P Hynynen M | 2002 | Cardiothorac Vasc Anesth2002，16，： | 1 |
| 18 | Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats显示文摘 | Erranta A Riutta A Fan M | 2012 | Am J Nephrol2012，35，5： | 1 |
| 19 | Follicle-stimulating hormone receptors appear earlier in the primate fetal testis than in the ovary 显示文摘 | Huhtaniemi IT Yamamoto M Ranta T | 1987 | J Clin Endocrinol Metab1987，65，6： | 1 |
| 20 | Hyperprolactinaemia and luteal insufficiency 显示文摘 | Seppala M Hirvonen E Ranta T | 1976 | Lancet1976，1，7953： | 1 |
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