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18篇 您的检索式:作者名="Rasmusson RL"
    题名 作者 年代 出处 被引量
1四种心肌克隆钾通道的表达和电生理记录显示文摘为建立一种研究离子通道的有效模型 ,笔者应用分子生物学技术 ,将包含有Kv1.4、Kv1.5、Herg和KvLQT1等几种心肌克隆钾离子 (K+ )通道cDNA的质粒经扩增 ,提取 ,以及纯化后转录为mRNA。经微注射技术分别将它们注射入克隆离子通道表达系统———非洲爪蟾卵母细胞内 ,然后应用膜片钳技术记录上述克隆离子通道电流。结果 :获得了四种克隆通道的电流 时间关系曲线 (I/t)和电流 电压关系曲线 (I/V)。结论 :本实验结果证明所采用的技术稳定可靠 ,并为今后开展克隆离子通道结构和功能的关系以及抗心律失常药物与离子通道相互作用的研究提供了坚实的基础。徐林 黄从新 蒋学俊 李晓艳 吴钢 唐哨勇 Duffey M Strauss HC Rasmusson RL 王世敏 2004中国心脏起搏与心电生理杂志2004,18,2:6
2Distinct tr ansient outward potassium current(Ito) phenotypes and distribution of fast-inacti vationg potassium channel alpha subunits in ferret left ventricular myocytes显示文摘 Campbell DL Rasmusson RL 1999J Gen Physiol1999,113,:1
3Inactivation of voltage-gated K+ channels显示文摘 Morales JM Eang S 1998Circ Res1998,20,:1
4Distinct transient outwrad potassium current(Ito)phenotypes and distribution of fast-inactivating potassium channel alpha subunits in ferret left ventricular myocytes显示文摘 Campbell DL Rasmusson RL 1999J Gen Physiol1999,113,:1
5Plant breeding progress and ge- netic diversity from de novo variation and elevated epistasis 显示文摘Rasmusson DC Phillips RL 1997Crop Science1997,37,2:1
6Inactivation of voltagegated cardiac K^+ channels显示文摘Rasmusson RL Morales M J Wang S 1998Circ Res1998,82,7:1
7Activation and inactivation kinetics of and E-4031-sensitive current from single ferret atrial myocytes显示文摘 Rasmusson RL Campbell DL 1996Biophys J1996,70,:1
8Inactivation of voltage-gated cardiac K^+ channels显示文摘Rasmusson RL Morales MJ Wang S 1998Circ Res1998,82,7:1
9The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes显示文摘Campbell DL Rasmusson RL Qu Y 1993J General Physiol1993,100,:1
10Functionally-distinct proton-binding in HERG suggests the presence of two binding sites 显示文摘Bett GC Rasmusson RL 2003Cell Biochem Biophys2003,39,3:1
11Inactivation of voltage-gated cardiac K^+ channels显示文摘Rasmusson RL Morales MJ Wang S 1998Circ Res1998,82,:1
12Cloning and characterization of an Ito-like potassium channel from ferret ventricle显示文摘Comer MB Campbell DL Rasmusson RL 1994Am J Physiol1994,267,42:1
13Inactivation of voltage-gated cardiac K+ channels显示文摘Rasmusson RL Morales MJ Wang S 1998Circ Res1998,82,:1
14Distinct transient outward potassium current (Ito) phenotypes and distribution of fast-inactivating potassium channel alpha subunits in ferret left ventricular myocytes显示文摘Brahmajothi M Campbell DL Rasmusson RL 1999J Gen Physiol1999,113,:1
15Cloning and characterization of an ho-like potassium channel from ferret ventricle 显示文摘Comer MB Campbell DL Rasmusson RL 1994Am J Physiol1994,267,42:1
16Distinct transient outward potassium current(Ito) phenotypes and distribution of fast inactivating potassium channel alpha subunits in ferret left ventricular myocytes显示文摘 Campbell DL Rasmusson RL 1999Gen Physiol1999,113,4:1
17Inactivation of voltage-gated cardiac K^+ channels 显示文摘Rasmusson RL Morales M J Wang S 1998Circ Res1998,82,7:1
18Distinct transient outward Potssum current (Ito) phenotypes and distribution of fast-inactivating potassium channel alpha-subunits in ferret left ventricular myocytes显示文摘Brahmajothi MV Campbell DL Rasmusson RL 1999J Gen Physiol1999,113,:1
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