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| 1 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 2 | Nonalcoholic fatty liver disease is associated with benign gastrointestinal disorders显示文摘AIM:To explore associations between nonalcoholic fatty liver disease(NAFLD)and benign gastrointestinal and pancreato-biliary disorders.METHODS:Patient demographics,diagnoses,and hospital outcomes from the 2010 Nationwide Inpatient Sample were analyzed.Chronic liver diseases were identified using International Classification of Diseases,the 9thRevision,Clinical Modification codes.Patients with NAFLD were compared to those with other chronic liver diseases for the endpoints of total hospital charges,disease severity,and hospital mortality.Multivariable stepwise logistic regression analyses to assess for the independent association of demographic,comorbidity,and diagnosis variables with the event of NAFLD(vs other chronic liver diseases)were also performed.RESULTS:Of 7800441 discharge records,32347(0.4%)and 271049(3.5%)included diagnoses of NAFLD and other chronic liver diseases,respectively.NAFLD patients were younger(average 52.3 years vs55.3 years),more often female(58.8%vs 41.6%),less often black(9.6%vs 18.6%),and were from higher income areas(23.7%vs 17.7%)compared to counterparts with other chronic liver diseases(all P<0.0001).Diabetes mellitus(43.4%vs 28.9%),hypertension(56.9%vs 47.6%),morbid obesity(36.9%vs 8.0%),dyslipidemia(37.9%vs 15.6%),and the metabolic syndrome(28.75%vs 8.8%)were all more common among NAFLD patients(all P<0.0001).The average total hospital charge($39607 vs$51665),disease severity scores,and intra-hospital mortality(0.9%vs6.0%)were lower among NALFD patients compared to those with other chronic liver diseases(all P<0.0001).Compared with other chronic liver diseases,NAFLD was significantly associated with diverticular disorders[OR=4.26(3.89-4.67)],inflammatory bowel diseases[OR=3.64(3.10-4.28)],gallstone related diseases[OR=3.59(3.40-3.79)],and benign pancreatitis[OR=2.95(2.79-3.12)]on multivariable logistic regression(all P<0.0001)when the latter disorders were the principal diagnoses on hospital discharge.Similar relationships were observed when the latter disorders were associated diagnoses on hospital discharge.CONCLUSION:NAFLD is associated with diverticular,inflammatory bowel,gallstone,and benign pancreatitis disorders.Compared with other liver diseases,patients with NAFLD have lower hospital charges and mortality. | Srinevas K Reddy Min Zhan H Richard Alexander Samer S El-Kamary | 2013 | World Journal of Gastroenterology2013，19，45： | 4 |
| 3 | Indium(llI) chloride/2-iodoxybenzoic acid: a novel reagent system for the conversion of indoles into isatins显示文摘 | Yadav JS Reddy B V S Reddy C h S | 2007 | Synthesis2007，5，： | 1 |
| 4 | Indentation penetration and perforation of composite laminates and sandwich panels under quasi-static and projectile loading显示文摘 | Wen H M Reddy T Y Reid S R | 1998 | Key Eng Mater1998，，1： | 1 |
| 5 | Selectivity of 4,5,6,7 -tetrabromo-benzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ( Ca-sein kinase-2')显示文摘 | Samo S Reddy H Meggio F | 2001 | FEBS Lett2001，496，1： | 1 |
| 6 | Promoting effect of bile acids in colon carcinogenensis in germ-flee and conventional F344 rats显示文摘 | Reddy B S Watanabe K Weisburger J H | | 0，，37： | 1 |
| 7 | Chemoprevention of colon carcinogenesis by dietary perillyl alcohol显示文摘 | Reddy B S Wang C X Samaha H | 1997 | Cancer Res1997，57，3： | 1 |
| 8 | Penetration and perforation of composite sandwich panels by hemispherical and conical projectiles显示文摘 | Reddy T Y Wen H M Reid S R | 1998 | Trans ASME J Pres Ves Tech1998，120，2： | 1 |
| 9 | Naturally occurring anticarcinogenic substances in foodstuffs显示文摘 | Fiala E S Reddy B S Weisburger J H | 1985 | Annu Rev Nutr1985，5，： | 1 |
| 10 | Deformation and failure of clamped beams under low speed impact loading 显示文摘 | Wen H M Reddy T Y Reid S R | 1995 | Int J Impact Eng1995，16，3： | 1 |
| 11 | Emulsion sta- bility-theoretical studies on simultaneous flocculation and creaming显示文摘 | REDDY S R MELIK D H FOGLER H S | 1981 | J Colloid Interface Sci1981，82，1： | 1 |
| 12 | Different signaling pathways of induced resistance by rhizobacteria in Arabi- dopsis thaliana against two pathovars of Pseudomonas sy- ringae 显示文摘 | Ryu C M Hu C H Reddy M S | 2003 | New Phytologist2003，160，： | 1 |
| 13 | Effect of sputtering power on the physical properties of de magnetron sputtered copper oxide thin films显示文摘 | REDDY A S PARK H H REDDY V S | 2008 | Mater Chem Phys2008，110，23： | 1 |
| 14 | Analytical properties of 2-acetylthiophene-4-phenyl-3-thiosemicarbazone: spectrophotometric determination of copper (Ⅱ) in edible oils and seeds显示文摘 | PRASAD N B L REDDY K H Reddy T S | 2003 | Indian Journal of Chemistry2003，42，1： | 1 |
| 15 | An optimal multiple thresh-old scheme for image segmentation显示文摘 | Reddi S S Rudin S F Keshavan H R | 1984 | Systems Man and Cybernetics IEEE Transactions on1984，1984，4： | 1 |
| 16 | Temperature regime and carbon dioxide enrichment alter cotton boll development and fiber properties 显示文摘 | REDDY K R DAVIDONIS G H JOHNSON S | 1999 | Apron J1999，91，： | 1 |
| 17 | Human lung tumor growth established in the lung and subcutaneous tissue of mice with severe combined immunodeficiency显示文摘 | Reddy S Piccione D Takita H | 1987 | Cancer Res1987，47，9： | 1 |
| 18 | Adsorption of reovirus by minerals and soils 显示文摘 | Moore R S Taylor D H Reddy M M | 2003 | Applied and Environmental Microbiology2003，，： | 1 |
| 19 | Low emissivity Ag/Ta/glass multilayer thin films deposited by sputtering显示文摘 | Park S H Lee K S Sivasankar Reddy A | 2011 | Journal of Applied Physics2011，110，06： | 1 |
| 20 | Mirowave thermoalysis: A convenient and rapid coupling of thiols using clayan in solvent free condition 显示文摘 | Meshrane H M Bandyopadhyay A Reddy G S | 2000 | Synth commun2000，30，： | 1 |
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