|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effectiveness of an intervention for reducing social stigma towards mental illness in adolescents显示文摘AIM: To evaluate the effectiveness of an intervention for reducing social stigma towards mental illness in adolescents. The effect of gender and knowledge of someone with mental illness was measured. METHODS: Two hundred and eighty secondary school students were evaluated using the Community Attitudes towards Mental Illness(CAMI) questionnaire. The schools were randomized and some received the intervention and others acted as the control group. The programme consisted of providing information via a documentary film and of contact with healthcare staff in order to reduce the social stigma within the school environment. RESULTS: The intervention was effective in reducing the CAMI authoritarianism and social restrictiveness subscales. The intervention showed significant changes in girls in terms of authoritarianism and social restrictiveness, while boys only showed significant changes in authoritarianism. Following the intervention, a significant reduction was found in authoritarianism and social restrictiveness in those who knew someone with mental illness, and only in authoritarianism in those who did not know anyone with mental illness. CONCLUSION: The intervention was effective to reduce social stigma towards people with mental illness, especially in the area of authoritarianism. Some differences were found depending on gender and whether or not the subjects knew someone with mental illness. | Regina Vila-Badia Francisco Martínez-Zambrano Otilia Arenas Emma Casas-Anguera Esther García-Morales Raúl Villellas José Ramón Martín María Belén Pérez-Franco Tamara Valduciel Diana Casellas Mar García-Franco Jose Miguel Joaquim Balsera Gemma Pascual Eugènia Julia Susana Ochoa | 2016 | World Journal of Psychiatry2016，6，2： | 4 |
| 2 | Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats显示文摘AIM To evaluate the sex-specific effects of a hydroalcoholic extract from Eugenia punicifolia(HEEP) leaves on gastric ulcer healing.METHODS In this rat study involving males, intact(cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid. A vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. Body weight was monitored throughout the treatment period. At the end of treatment, the rats were euthanized and the following in vivo and in vitro investigations were performed: macroscopic examination of the lesion area and organ weights, biochemical analysis, zymography, and evaluation of protein expression levels. Additionally, the concentration-dependent effect of HEEP was evaluated in terms of subacute toxicity and cytotoxicity.RESULTS Compared to the vehicle, HEEP demonstrated a great healing capacity by substantially reducing the ulcerative lesion area in males(52.44%), intact females(85.22%), and ovariectomized females(65.47%), confirming that HEEP accelerates the healing of acetic acidinduced gastric lesions and suggesting that this effect is modulated by female sex hormones. The antiulcer effect of HEEP was mediated by prostaglandin E2 only in male rats. Overall, the beneficial effect of HEEP was the highest in intact females. Notably, HEEP promoted the expression of vascular endothelial growth factor(intact vs ovariectomized females) and decreased the expression of Caspase-8 and Bcl-2(intact female vs male or ovariectomized female). Additionally, HEEP enhanced fibroblast proliferation and migration into a wounded area in vitro, confirming its healing effect. Finally, no sign of subacute toxicity or cytotoxicity of HEEP was observed.CONCLUSION In gastric ulcers, HEEP-induced healing(modulated by female sex hormones; in males, mediated by prostaglandin) involves extracellular matrix remodeling, with gastric mucosa cell proliferation and migration. | Larissa Lucena Périco Vinícius Peixoto Rodrigues Rie Ohara Gabriela Bueno Vania Vasti Alfieri Nunes Raquel Cássia dos Santos Ana Carolina Lima Camargo Luis Antuio Justulin Joior Sérgio Faloni de Andrade Viviane Miranda Bispo Steimbach Luísa Mota da Silva Lúcia Regina Machado da Rocha Wagner Vilegas Catarina dos Santos Clélia Akiko Hiruma-Lima | 2018 | World Journal of Gastroenterology2018，24，38： | 3 |
| 3 | Can baseline ML Flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil显示文摘Background:The predictive value of the serology to detection of IgM against the Mycobacterium leprae-derived phenolic glycolipid-I/PGL-I to identify leprosy patients who are at higher risk of developing reactions remains controversial.Whether baseline results of the ML Flow test can predict leprosy reactions was investigated among a cohort of patients enrolled in The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil(U-MDT/CT-BR).Methods:This was a descriptive study focusing on the main clinical manifestations of leprosy patients enrolled in the U-MDT/CT-BR from March 2007 to February 2012 at two Brazilian leprosy reference centers.For research purposes,753 leprosy patients were categorized according to a modified Ridley-Jopling(R&J)classification and according to the development of leprosy reactions(reversal reaction/RR and erythema nodosum leprosum/ENL),and whether they had a positive or negative bacillary index/BI.Results:More than half of the patients(55.5%)reported leprosy reaction:18.3%(138/753)had a RR and 5.4%(41/753)had ENL.Leprosy reactions were more frequent in the first year following diagnosis,as seen in 27%(205/753)of patients,while 19%(142/753)developed reactions during subsequent follow-up.Similar frequencies of leprosy reactions and other clinical manifestations were observed in paucibacillary(PB)and multibacillary(MB)leprosy patients treated with U-MDT and regular MDT(R-MDT)(P=0.43 and P=0.61,respectively).Compared with PB patients,leprosy reactions were significantly more frequent in MB patients with a high BI,and more patients developed RR than ENL.However,RR and neuritis were also reported in patients with a negative BI.At baseline,the highest rate of ML Flow positivity was observed in patients with a positive BI,especially those who developed ENL,followed by patients who had neuritis and RR.Among reaction-free patients,81.9%were ML Flow positive,however,the differences were not statistically significant compared to reactional patients(P=0.45).Conclusions:MB and PB patients treated with R-MDT and U-MDT showed similar frequencies of RR and other clinical manifestations.Positive ML Flow tests were associated with MB leprosy and BI positivity.However,ML Flow test results at baseline showed limited sensitivity and specificity for predicting the development of leprosy reactions. | Emerith Mayra Hungria Regiane Morillas Oliveira Gerson Oliveira Penna Lúcio Cartaxo Aderaldo Maria Araci de Andrade Pontes Rossilene Cruz Heitor de SáGonçalves Maria Lúcia Fernandes Penna Ligia Regina Franco Sansigolo Kerr Mariane Martins de Araújo Stefani Samira Bührer-Sékula | 2016 | Infectious Diseases of Poverty2016，5，1： | 2 |
| 4 | Auricular Acupuncture with Laser 显示文摘 | Regina R Gerhard L Frank B | 2013 | Evid Based Complement Ahernat Med2013，2013，98： | 1 |
| 5 | Identification of polymorphic outer membrane protein of Chlamydia psittaic 6BC 显示文摘 | Regina J T David L Thomas P H | 2001 | Infect and Immun2001，69，： | 1 |
| 6 | Naphthenic Acids, Total Acid Number and Sulfur Content Profile Cha- racterization in Isthmus and Maya Crude Oils显示文摘 | GEORGINA C L CARLA R L REGINA E A | 2004 | Fuel2004，83，： | 1 |
| 7 | Fungi from geothermal soils in Yellowstone National Park显示文摘 | Regina S R Anastassial L Kathy BS | 1999 | Applied Environment Microbiology1999，65，12： | 1 |
| 8 | Algal bioaccumulation of triclocarban, triclosan, and methyt-triclosan in a North Texas wastewater treatment plant receiving stream显示文摘 | MELINDA A C REGINA E E THOMAS W L | 2007 | Chemosphere2007，67，10： | 1 |
| 9 | Brain Region-Selective Mechanisms Contribute to the Progression of Cerebral Alterations in Acute Liver Failure in Rats显示文摘 | Omar Cauli Pilar López–Larrubia Regina Rodrigo Ana Agusti Jordi Boix Laura Nieto–Charques Sebastián Cerdán Vicente Felipo | 2011 | Gastroenterology2011，，2： | 1 |
| 10 | Altitude influence on the quality of 'Chardonnay' and 'Pinot Noir' grapes in the state of Minas Gerais显示文摘 | de Albuquerque Regina M do Carmo E L Fonseca A R | 2010 | Revista Brasileira de Fruticultura2010，32，1： | 1 |
| 11 | Process configurations adapted to membrane bioreactors for enhanced biological phosphorous and nitrogen removal显示文摘 | Boris L Regina G Chritian A | 2002 | Desalination2002，149，3： | 1 |
| 12 | Surveillance of nosocomial infections in a neurology intensive care unit显示文摘 | Markus Dettenkofer Winfried Ebner Thomas Els Regina Babikir Carl Lücking Klaus Pelz Henning Rüden Franz Daschner | 2001 | Journal of Neurology2001，，11： | 1 |
| 13 | Follicular mucinosis, a critical reappraisal of clinicopathologic feature and association with mycosis fungoides and sezary syndrome 显示文摘 | Cerroni L Regina FP Back B | 2002 | Arch Dermatol2002，138，： | 1 |
| 14 | Sensitive and Robust One-Tube Real-Time Reverse Transcriptase-Polymerase Chain Reaction to Quantify SIV RNA Load:Comparison of One-versus Two-Enzyme Systems显示文摘 | Regina H L Ryan K S Vladimir L | 2000 | AIDS2000，16，13： | 1 |
| 15 | Prevalence of infectious hypodermal and hematopoietic necrosis virus(IHHNV)in Penaeus vannamei cultured in northeastern Brazil显示文摘 | REGINA LGIAG R MAURCIO | 2009 | Aquaculture2009，288，2： | 1 |
| 16 | Aging effect on the refleetivity measurements of polyc hloroprene matrices containing carbon black and carbonyl-iron powder显示文摘 | Magali S P Maria L G Regina C R N | 2001 | Poly- mer Degradation and Stability2001，73，1： | 1 |
| 17 | The use of mediation and ontology technologies for software component information retrieval显示文摘 | REGINA M M B MARA M CLAUDIA M L W | 2001 | ACM Sigsoft Software Engineering Notes2001，26，3： | 1 |
| 18 | Hydroxylation Increases the Neurotoxic Potential of BDE-47 to Affect Exocytosis and Calcium Homeostasis in PC12 Cells显示文摘 | Dingemans Milou M L Groot Aart de Kleef Regina G D M van Bergman ?ke Berg Martin van den Vijverberg Henk P M Westerink Remco H S | 2008 | Environmental Health Perspectives2008，，5： | 1 |
| 19 | 核废料埋藏点候选场所生物圈描述的策略:生态系统和景观模型的结合显示文摘为给核废料深埋藏点的许可申请提供必要数据,瑞典核燃料及核废料管理公司已在瑞典境内的两个地点进行了现场调查。本文提出将位点特异性生态系统数据与安全评估研究和环境影响评价所必需的空间模型相结合的策略。对生态系统位点特异性的描述是通过从原始数据建立学科特异性模型,识别位点功能单位间的相互作用、物质积累和流动来实现的。概念模型对系统过程量化特征的确定是一个有用的初始工具,可能揭示新的学科界面,提供促进对生态系统特征和景观功能特性之间关系了解的各种新机会。这种生态系统与景观特性整合模型在深埋藏点安全评估中具有重要作用。 | Tobias Lindborg Regina Lindborg Anders Lfgren Bjrn Sderbck Clare Bradshaw Ulrik Kautsky 梁虹 | 2006 | AMBIO-人类环境杂志2006，35，8： | 1 |
| 20 | Odyssey-Search: A multi - agent system for component information search and retrieval 显示文摘 | Regina M M Braga Cla'udia M L Wemer Malta Mattoso | 2006 | The Journal of Systems and Software2006，，79： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员