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| 1 | Global burden, distribution, and interventions for infectious diseases of poverty显示文摘Infectious diseases of poverty(IDoP)disproportionately affect the poorest population in the world and contribute to a cycle of poverty as a result of decreased productivity ensuing from long-term illness,disability,and social stigma.In 2010,the global deaths from HIV/AIDS have increased to 1.5 million and malaria mortality rose to 1.17 million.Mortality from neglected tropical diseases rose to 152,000,while tuberculosis killed 1.2 million people that same year.Substantial regional variations exist in the distribution of these diseases as they are primarily concentrated in rural areas of Sub-Saharan Africa,Asia,and Latin America,with geographic overlap and high levels of co-infection.Evidence-based interventions exist to prevent and control these diseases,however,the coverage still remains low with an emerging challenge of antimicrobial resistance.Therefore,community-based delivery platforms are increasingly being advocated to ensure sustainability and combat co-infections.Because of the high morbidity and mortality burden of these diseases,especially in resource-poor settings,it is imperative to conduct a systematic review to identify strategies to prevent and control these diseases.Therefore,we attempted to evaluate the effectiveness of one of these strategies,that is community-based delivery for the prevention and treatment of IDoP.In this paper,we describe the burden,epidemiology,and potential interventions for IDoP.In subsequent papers of this series,we describe the analytical framework and the methodology used to guide the systematic reviews,and report the findings and interpretations of our analyses of the impact of community-based strategies on individual IDoPs. | Zulfiqar A Bhutta Johannes Sommerfeld Zohra S Lassi Rehana A Salam Jai K Das | 2014 | Infectious Diseases of Poverty2014，3，1： | 21 |
| 2 | The conceptual framework and assessment methodology for the systematic reviews of community-based interventions for the prevention and control of infectious diseases of poverty显示文摘This paper describes the conceptual framework and the methodology used to guide the systematic reviews of community-based interventions(CBIs)for the prevention and control of infectious diseases of poverty(IDoP).We adapted the conceptual framework from the 3ie work on the‘Community-Based Intervention Packages for Preventing Maternal Morbidity and Mortality and Improving Neonatal Outcomes’to aid in the analyzing of the existing CBIs for IDoP.The conceptual framework revolves around objectives,inputs,processes,outputs,outcomes,and impacts showing the theoretical linkages between the delivery of the interventions targeting these diseases through various community delivery platforms and the consequent health impacts.We also describe the methodology undertaken to conduct the systematic reviews and the meta-analyses. | Zohra S Lassi Rehana A Salam Jai K Das Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 5 |
| 3 | 兰坪金顶蜂子山铅锌矿床的构造控矿:来自三维空间数据分析的证据显示文摘滇西金顶超大型铅锌矿床的热液成矿和构造控矿特点突出,对其主要容矿岩石和断层耦合控矿机制仍不清楚。利用三维空间数据分析方法,对代表性的蜂子山铅锌矿床开展了矿化结构及其空间展布特征的综合研究。结果表明:Pb和Zn矿化中心呈现出东西向分带及差异性分段富集的特点,空间上并与黄铁矿、天青石(—重晶石)和石膏矿体共置;成矿流体的运聚受近SN向逆冲断层和近EW向走滑断层的共同控制,为其提供通道和沉淀空间;而金顶群(N_(1)j)的湖相氧化性含矿卤水在两组方向断层的联合驱动下,在三合洞组上段(T_(3)s^(3))地层中与其赋存的还原性流体幕式混合成矿,是该矿床发育的重要机制。尤其是,近SN向逆冲断层和近EW向走滑断层联合控矿特征的发现,为深入理解金顶超大型铅锌矿床成矿作用及指导找矿勘查提供了新的依据。 | 刘靖坤 薛传东 薛力鹏 杨天云露 曾招阳 姚远涛 LENH Phan Duc GHAZI Rehana | 2021 | 地球科学进展2021，36，10： | 4 |
| 4 | Neurotransmitter receptors on microglia显示文摘As the resident immune cells in the central nervous system,microglia have long been hypothesised to promote neuroinflammation and exacerbate neurotoxicity.However,this traditional view has undergone recent revision as evidence has accumulated that microglia exert beneficial and detrimental effects depending on activation status,polarisation phenotype and cellular context.A variety of neurotransmitter receptors are expressed on microglia and help mediate the bidirectional communication between neurons and microglia.Here we review data supporting the importance of neurotransmitter receptors on microglia,with a special emphasis on glutamate,γ-aminobutyric acid(GABA),norepinephrine,cannabinoid and acetylcholine receptors.We summarise evidence favouring a significant role for neurotransmitter receptors in modulating microglial activation,phagocytic clearance and phenotypic polarisation.Elucidating the effects of neurotransmitter receptors on microglia and dissecting the underlying mechanisms may help accelerate the discovery of novel drugs that tap the therapeutic potential of microglia. | Huan Liu Rehana K Leak Xiaoming Hu | 2016 | Stroke & Vascular Neurology2016，1，2： | 3 |
| 5 | Impact of community-based interventions on HIV knowledge, attitudes, and transmission显示文摘In 2012,an estimated 35.3 million people lived with HIV,while approximately two million new HIV infections were reported.Community-based interventions(CBIs)for the prevention and control of HIV allow increased access and ease availability of medical care to population at risk,or already infected with,HIV.This paper evaluates the impact of CBIs on HIV knowledge,attitudes,and transmission.We included 39 studies on educational activities,counseling sessions,home visits,mentoring,women’s groups,peer leadership,and street outreach activities in community settings that aimed to increase awareness on HIV/AIDS risk factors and ensure treatment adherence.Our review findings suggest that CBIs to increase HIV awareness and risk reduction are effective in improving knowledge,attitudes,and practice outcomes as evidenced by the increased knowledge scores for HIV/AIDS(SMD:0.66,95%CI:0.25,1.07),protected sexual encounters(RR:1.19,95%CI:1.13,1.25),condom use(SMD:0.96,95%CI:0.03,1.58),and decreased frequency of sexual intercourse(RR:0.76,95%CI:0.61,0.96).Analysis shows that CBIs did not have any significant impact on scores for self-efficacy and communication.We found very limited evidence on community-based management for HIV infected population and prevention of mother-to-child transmission(MTCT)for HIV-infected pregnant women.Qualitative synthesis suggests that establishment of community support at the onset of HIV prevention programs leads to community acceptance and engagement.School-based delivery of HIV prevention education and contraceptive distribution have also been advocated as potential strategies to target high-risk youth group.Future studies should focus on evaluating the effectiveness of community delivery platforms for prevention of MTCT,and various emerging models of care to improve morbidity and mortality outcomes. | Rehana A Salam Sarah Haroon Hashim H Ahmed Jai K Das Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 3 |
| 6 | Impact of community-based interventions for the prevention and control of malaria on intervention coverage and health outcomes for the prevention and control of malaria显示文摘In this paper,we aim to evaluate the effectiveness of community-based interventions(CBIs)for the prevention and management of malaria.We conducted a systematic review and identified 42 studies for inclusion.Twenty-five of the included studies evaluated the impact of the community-based distribution of insecticide-treated nets(ITNs),indoor residual spraying(IRS),or impregnated bed sheets;14 studies evaluated intermittent preventive therapy(IPT)delivered in community settings;two studies focused on community-based education for malaria prevention;and one study evaluated environmental management through drain cleaning.Our analysis suggests that,overall,the community-based delivery of interventions to prevent and control malaria resulted in a significant increase in ITNs ownership(RR:2.16,95%CI:1.86,2.52)and usage(RR:1.77,95%CI:1.48,2.11).However,usage of ITNs was limited to two-thirds of the population who owned them.Community-based strategies also led to a significant decrease in parasitemia(RR:0.56,95%CI:0.42,0.74),malaria prevalence(RR:0.46,95%CI:0.29,0.73),malaria incidence(RR:0.70,95%CI:0.54,0.90),and anemia prevalence(RR:0.79,95%CI:0.64,0.97).We found a non-significant impact on splenomegaly,birth outcomes(low birth weight,prematurity,stillbirth/miscarriage),anthropometric measures(stunting,wasting,and underweight),and mortality(all-cause and malaria-specific).The subgroup analysis suggested that community-based distribution of ITNs,impregnated bed sheets and IRS,and IPT are effective strategies.Qualitative synthesis suggests that high coverage could be achieved at a lower cost with the integration of CBIs with existing antenatal care and immunization campaigns.Community-based delivery of interventions to prevent and control malaria are effective strategies to improve coverage and access and reduce malaria burden,however,efforts should also be concerted to prevent over diagnosis and drug resistance. | Rehana A Salam Jai K Das Zohra S Lassi Zulfiqar A Bhutta | 2014 | Infectious Diseases of Poverty2014，3，1： | 2 |
| 7 | Tackling the existing burden of infectious diseases in the developing world: existing gaps and the way forward显示文摘This series evaluates the effectiveness of community-based interventions(CBIs)to prevent and control infectious diseases of poverty(IDoP).Evidence from our reviews suggests that CBIs and school-based delivery platforms are effective in averting risk behaviors and reducing the disease burden.Co-implementation of interventions through existing community-based programs including immunization campaigns,antenatal care and maternal and child health programs have the potential to scale-up interventions for IDoP.Future research should focus on the process of developing and implementing efficient community-based programs through a comprehensive approach,and to gauge the effectiveness of various existing delivery models in order to improve morbidity and mortality outcomes. | Zulfiqar A Bhutta Rehana A Salam Jai K Das | 2014 | Infectious Diseases of Poverty2014，3，1： | 2 |
| 8 | Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver显示文摘 | Sajad Hussain Arif Shams-ul-Bari Nazir Ahmad Wani Showkat Ahmad Zargar Mehmood Ahmad Wani Rehana Tabassum Zahoor Hussain Ajaz Ahmad Baba Riyaz Ahmad Lone | 2008 | International Journal of Surgery2008，，6： | 2 |
| 9 | Catalytic Hydrogenation of Acetic Acid to Acetaldehyde: Synergistic Effect of Bifunctional Co/Ce-Fe Oxide Solid Solution Catalysts显示文摘The large-scale industrial production of acetic acid (HAc) from carbonylation of methanol has enabled intense research interest from direct hydrogenation of HAc to acetaldehyde (AA).Herein,a series of cerium-iron oxide solid solution supported metallic cobalt catalysts were prepared by modified sol-gel method and were applied in gas-phase hydrogenation of HAc to AA.A synergistic effect between the hydrogenation metal cobalt and Ce-Fe oxide solid solution is revealed.Specifically,oxygen vacancies provide the active sites for adsorption of HAc,while highly uniformly dispersed metallic Co adsorbs H2 and activates the reduction of HAc into AA.Moreover,the metallic Co can also assist the cyclical conversion between Fe3+/Fe2+ and Ce3+/Ce4+ on the surface of Ce1.xFexO2-δ supports.The unique effect substantially enhances the ability of the support material to rapidly capture oxygen atoms from HAc.It is found that the catalyst of 5% Co/Ce0.8Fe0.2O2-δ with the highest concentration of oxygen vacancy presents the best catalytic performance (i.e.acetaldehyde yield reaches 49.9%) under the optimal reaction conditions (i.e.623 K and H2 flow rate =10 mL/min).This work indicates that the Co/Ce-Fe oxide solid solution catalyst can be potentially used for the selective hydrogenation from HAc to AA.The synergy between the metallic Co and Ce1-xFexO2-δ revealed can be extended to the design of other composite catalysts. | Naixu Li Qi Zhang Rehana Bibi Quanhao Shen Richard Ngulube Yunyi Liu Jiancheng Zhou | 2019 | Chinese Journal of Chemistry2019，37，7： | 2 |
| 10 | Enviro-Friendly Synthesis of Silver Nanoparticles Using Berberis lycium Leaf Extract and Their Antibacterial Efficacy显示文摘In the present study,an enviro-friendly synthesis of silver nanoparticles from Berberis lycium Royle leaf extract and their antibacterial efficacy against five pathogenic bacteria were investigated.This biosynthesis technique is proved to be advantageous over physical and chemical methods as no toxic chemicals are used.The structural and morphological characterization was made by UV-visible spectroscopy,scanning electron microscopy,and transmission electron microscopy.The synthesized nanoparticles were oval,rectangular,and spherical in shape,size ranges from 8 to 100 nm and exhibited an absorption peak at 458 nm.The biosynthesized silver nanoparticles have shown good antibacterial effect toward tested bacteria.It is believed that these biosynthesized silver nanoparticles can play a vital role in nano-based products in future. | Ansar Mehmood Ghulam Murtaza Tariq Mahmood Bhatti Rehana Kausar | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，1： | 1 |
| 11 | miR-9 and let-7g enhance the sensitivity to ionizing radiation by sup pression of NFκB1显示文摘 | HIMANSHU A REHANA Q SHUNZI J | 2011 | Experimental and Molecular Medicine2011，43，5： | 1 |
| 12 | Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke显示文摘 | Jiayin Wang Yejie Shi Lili Zhang Feng Zhang Xiaoming Hu Wenting Zhang Rehana K. Leak Yanqin Gao Ling Chen Jun Chen | 2014 | Neurobiology of Disease2014，，： | 1 |
| 13 | Pelvic floor exercise for urinary incontinence: A systematic literature review显示文摘 | Natalia Price Rehana Dawood Simon R. Jackson | 2010 | Maturitas2010，，4： | 1 |
| 14 | 沙特阿拉伯电子医疗云利用中的隐私和安全问题研究(英文)显示文摘云计算是当前信息和通信技术(ICT)领域最受欢迎的趋势之一。该技术通过集中数据存储和处理技术获得高效的计算。由于其巨大的优势,该技术迅速成熟,并被包括政府、商业、医院和教育部门的许多部门采用。信息技术在健康和病人护理领域发挥着重要作用,同时云计算也开始逐渐发挥作用。然而,云计算作为医疗IT(HIT)的构成部分,尽管利用起来优点显著,但是安全性、隐私、可靠性、集成和数据可移植性是实施中的重要挑战和障碍,也是云计算在沙特阿拉伯应用缓慢的主要原因。当云应用于电子医疗时,安全和隐私问题是最重要的。这些领域的问题应该得到解决,以使云计算可以成功为所有领域应用。患者、医疗保健提供者和其他相关组织关注客户信息的隐私问题,并希望看到适当的措施来保护隐私。在本文中,研究人员将讨论在云计算电子医疗应用和可用立法方面的隐私和安全挑战,为应对沙特阿拉伯云利用中的挑战提供可能的解决方案。 | Emna Chikhaoui Jawahitha Sarabdeen Rehana Parveen | 2017 | 档案学研究2017，，S1： | 1 |
| 15 | Selectivity reversal and dimerization of chromate in the exchanger Amberlite IRA-400 显示文摘 | MUSTAFA S BASHIR H REHANA N | 1997 | Reactive & Functional Polymers1997，34，： | 1 |
| 16 | New roles of the multidimensional adipokine: Chemerin显示文摘 | Syeda Sadia Fatima Rehana Rehman Mukhtiar Baig Taseer Ahmed Khan | 2014 | Peptides2014，，： | 1 |
| 17 | Epigenetic Regulation of Inflammatory Cytokines and Associated Genes in Human Malignancies显示文摘 | Rehana Yasmin Sami Siraj Amjad Hassan Abdul Rehman Khan Rashda Abbasi Nafees Ahmad Marc Pouliot | 2015 | Mediators of Inflammation2015，，： | 1 |
| 18 | Soil organic carbon and physical properties as affected by long-term application of FYM and inorganic fertilizers in maize-wheat system显示文摘 | Rehana R Kukal S S Hira G S | 2008 | Soil & Tillage Research2008，101，： | 1 |
| 19 | An imprecise fuzzy risk approach for water quality management of a river system 显示文摘 | REHANA S MUJUMDAR P P | 2009 | J Environ Manage2009，90，： | 1 |
| 20 | Variation in accumulationof heavy metals in different verities of sunflow-nique显示文摘 | Rehana Ansari Tasneem Gul Kazi MuhammadKhan Jamali | 2009 | Food Chemistry2009，115，： | 1 |
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