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| 1 | Type 2 diabetes mellitus and CA 19-9 levels显示文摘AIM:To prospectively investigate serum CA 19-9 levels in type 2 diabetic patients in comparison with age-and gender-matched control subjects. METHODS:We recorded duration of diabetes and examined fasting glucose levels,HbA1c levels and serum CA 19-9 levels in 76 type 2 diabetic patients and 76 controls.Abdominal CT was performed in order to eliminate abdominal malignancy in the diabetic and control groups. RESULTS:The average CA 19-9 level was 46.0±22.4 U/mL for diabetic patients whereas it was 9.97±7.1 U/mL for the control group(P<0.001).Regression analysis showed a positive correlation between diabetes and CA 19-9 independent from age,gender,glucose level and HbA1c level(t=8.8,P<001).Two of the diabetic patients were excluded from the study because of abdominal malignancy shown by CT at the initial evaluation.For all patients,abdominal CT showed no pancreatic abnormalities. CONCLUSION:CA 19-9 is a tumor-associated antigen, which is elevated in pancreatic,upper gastrointestinal tract,ovarian hepatocellular,and colorectal cancers,as well as in inflammatory conditions of the hepatobiliary system,biliary obstruction and in thyroid diseases. Diabetes has been claimed to be a risk factor for pancreatic cancer,which is increasing its incidence and has one of the lowest survival rates of all cancers.CA 19-9 is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes.We propose that a higher cut- off value of CA 19-9 should be used in diabetics to differentiate benign and malignant pancreatic disease, and subtle elevations of CA 19-9 in diabetics should be considered as the indication of exocrine pancreatic dysfunction. | Oya Uygur-Bayramicli Resat Dabak Ekrem Orbay Can Dolapclo■lu Mehmet Sargin Gamze Kilico■lu Yüksel Güleryüzlü Alpaslan Mayada■li | 2007 | World Journal of Gastroenterology2007，13，40： | 63 |
| 2 | A clinical dilemma:abdominal tuberculosis显示文摘AIM: To evaluate the clinical, radiological and microbiological properties of abdominal tuberculosis (TB) and to discuss methods needed to get the diagnosis.METHODS: Thirty-one patients diagnosed as abdominal TB between March 1998 and December 2001 at the Gastroenterology Department of Kartal State Hospital,Istanbul, Turkey were evaluated prospectively. Complete physical examination, medical and family history, blood count erythrocyte sedimentation rate, routine biochemical tests,Mantoux skin test, chest X-ray and abdominal ultrasonography (USG) were performed in all cases, whereas microbiological examination of ascites, upper gastrointestinal endoscopy, colonoscopy or barium enema, abdominal tomography, mediastinoscopy, laparoscopy or laparotomy were done when needed.RESULTS: The median age of patients (14 females, 17males) was 34.2 years (range 15-65 years). The most frequent symptoms were abdominal pain and weight loss.Eleven patients had active pulmonary TB. The most common abdominal USG findings were ascites and hepatomegaly. Ascitic fluid analysis performed in 13 patients was found to be exudative and acid resistant bacilli were present in smear and cultured only in one patient with BacTec (3.2 %). Upper gastrointestinal endoscopy yielded nonspecific findings in 16 patients. Colonoscopy performed in 20 patients showed ulcers in 9 (45 %), nodules in 2 (10 %)and, stricture, polypoid lesions, granulomatous findings in terminal ileum and rectal fistula each in one patient (5 %).Laparoscopy on 4 patients showed dilated bowel loops,thickening in the mesentery, multiple ulcers and tubercles on the peritoneum. Patients with abdominal TB were divided into three groups according to the type of involvement.Fifteen patients (48 %) had intestinal TB, L1 patients (35.2 %) had tuberculous peritonitis and 5 (16.8 %)tuberculous lymphadenitis. The diagnosis of abdominal TB was confirmed microbiologically in 5 (16 %) and histopathologically in 19 patients (60.8 %). The remaining nine patients (28.8 %) had been diagnosed by a positive response to antituberculous treatment.CONCLUSION: Neither clinical signs, laboratory, radiological and endoscopic methods nor bacteriological and histopathological findings provide a gold standard by themselves in the diagnosis of abdominal TB. However, an algorithm of these diagnostic methods leads to considerably higher precision in the diagnosis of this insidious disease which primarily necessitate a clinical awareness of this serious health problem. | Oya Uygur-Bayramili Gül Dabak Resat Dabak | 2003 | World Journal of Gastroenterology2003，9，5： | 20 |
| 3 | N-acetylcysteine attenuates alcohol-induced oxidative stess in rats显示文摘AIM: To investigate free-radical scavenger effect of nacetylcysteine in rats intragastrically fed with ethanol.METHODS: Twenty-four rats divided into three groups were fed with ethanol (6 g/kg/day, Group 1), ethanol and nacetylcysteine (1 g/kg, Group 2), or isocaloric dextrose (control group, Group 3) for 4 weeks. Then animals were sacrificed under ether anesthesia, and intracardiac blood and liver tissues were obtained. Measurements were made in both serum and homogenized liver tissues.Malondialdehyde (MDA) level was measured by TBARS method. Glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) levels were studied by commercial kits.Kruskal-Wallis test was used for statistical analysis.RESULTS: ALT and AST in Group 1 (154 U/L and 302 U/L,respectively) were higher than those in Group 2 (94 U/L and 155 U/L) and Group 3 (99 U/L and 168 U/L) (P=0.001for both). Serum and tissue levels of MDA in Group 1 (1.84nmol/mL and 96 nmol/100 mg-protein) were higher than that in Group 2 (0.91 nmol/mL and 64 nmol/100 mg protein)and Group 3 (0.94 nmol/mL and 49 nmol/100 mg-protein)(P<0.001 for both). On the other hand, serum GSH-Px level in Group 1 (8.21 U/g Hb) was lower than that in Group 2(16 U/g Hb) and Group 3 (16 U/g-Hb) (P<0.001). Serum and liver tissue levels of SOD in Group 1 (11 U/mL and 26U/100 mg-protein) were lower than that in Group 2 (18 U/mL and 60 U/100 mg protein) and Group 3 (20 U/mL and 60 U/100 mg-protein) (P<0.001 for both).CONCLUSION: Ethanol-induced liver damage was associated with oxidative stress, and co-administration of n-acetylcysteine attenuates this damage effectively in rat model. | Resat Ozaras Veysel Tahan Seval Aydin Hafize Uzun Safiye Kaya Hakan Senturk | 2003 | World Journal of Gastroenterology2003，9，4： | 9 |
| 4 | N-acetylcysteine attenuates alcohol-induced oxidative stress in the rat显示文摘AIM: There is increasing evidence that alcohol-induced liverdamage may be associated with increased oxidative stress.We aimed to investigate free-radical scavenger effect of n-acetylcysteine in rats intragastrically fed with ethanol.METHODS: Twenty-four rats divided into three groups werefed with ethanol (6 g/kg/day, Group 1), ethanol and n-acetylcysteine (1 g/kg, Group 2), or isocaloric dextrose(control group, Group 3) for 4 weeks. Then animals weresacrificed under ether anesthesia, intracardiac blood andliver tissues were obtained. Measurements were performedboth in serum and in homogenized liver tissues.Malondialdehyde (MDA) level was measured by TBARSmethod. Glutathione peroxidase (GSH-Px) and superoxidedismutase (SOD) levels were studied by commercial kits.Kruskal-Wallis test was used for statistical analysis.RESULTS: ALT and AST in Group 1 (154 U/Land 302 U/L,respectively) were higher than those in Group 2 (94 U/L and155 U/L) and Group 3 (99 U/L and 168 U/L) (P=0.001 forboth). Serum and tissue levels of MDA in Group 1 (1.84 nmol/mL and 96 nmol/100 mg-protein) were higher than Group 2(0.91 nmol/mL and 64 nmol/100 mg-protein) and Group 3(0.94 nmol/mL and 49 nmol/100 mg-protein) (P<0.001 forboth). On the other hand, serum GSH-Px level in Group 1(8.21 U/g-Hb) was lower than Group 2 (16 U/g-Hb) andGroup 3 (16 U/g-Hb) (P<0.001). Serum and liver tissue levelsof SOD in Group 1 (11 U/mL and 26 U/100 mg-protein)were lower than Group 2 (18 U/mL and 60 U/100 mg-protein)and Group 3 (20 U/mL and 60 U/100 mg-protein) (P<0.001for both).CONCLUSION: This study demonstrated that ethanol-induced liver damage is associated with oxidative stress,and co-administration of n-acetylcysteine attenuates thisdamage effectively in rat model. | Resat Ozaras Veysel Tahan Seval Aydin Hafize Uzun Safiye Kaya Hakan Senturk | 2003 | World Journal of Gastroenterology2003，9，1： | 7 |
| 5 | Use of the molybdenum-thiocyanate-rhodamine-6G ternary complex for spectrophotometric molybdenum determination without extraction显示文摘 | Hayati Filik Esma Tatem Resat Apak | 2004 | Analytiea Chimica Acta2004，505，： | 1 |
| 6 | Modeling of cadmium(Ⅱ) adsorption on kaolinite-based clays in the absence and presence of humic acid显示文摘 | Hizal Jülide Apark Resat | 2006 | Applied Clay Science2006，32，34： | 1 |
| 7 | Heavy Metal Cation Retention by Unconventional Sorbents(Red Muds and Fly Ashes)显示文摘 | Resat Apak Esma Tütem Mehmet Hügül | 1998 | Wat Res1998，32，2： | 1 |
| 8 | Assessment of structurally controlled slope failure mechanisms and remedial design consider- ations at a feldspar open pit mine, Western Turkey显示文摘 | Tanyas Hakan Ulusay Resat | 2013 | Engineering Geology2013，155，： | 1 |
| 9 | Risk of endocrine pancreatic insufficiency in patients receiving adjuvant chemoradiation for resected gastric cancer显示文摘 | Cengiz Gemici Mehmet Sargin Oya Uygur-Bayramicli Alpaslan Mayadagli Gokhan Yaprak Resat Dabak Mihriban Kocak | 2013 | Radiotherapy and Oncology2013，，2： | 1 |
| 10 | The sensitivity and specificity of Brucella agglutination tests 显示文摘 | All Merta Resat Ozaras Fehmi Tabak etal | 2003 | Diagnostic Microbiology and Infectious Disease2003，46，： | 1 |
| 11 | The sensitivity and specificity of Brucella agglutination tests 显示文摘 | Mert A Resat Ozaras R Tabak F | 2003 | Diag Microbiol Infect Dis2003，46，4： | 1 |
| 12 | An optical fibre reflectance sensor for p-aminophenol determination based on tetrahydroxycalixarene as sensing reagent 显示文摘 | Hayati F Duygu A Resat A | 2008 | Sens Actuators B2008，136，1： | 1 |
| 13 | Modeling of copper(II)and lead(II)adsorption on kaolinite-based clay minerals individually and in the presence of humic acid显示文摘 | Jülide Hizal Resat Apak | 2006 | Journal of Colloid and Interface Science2006，295，1： | 1 |
| 14 | Evaluation of site amplification and site period using different methods for an earthquake-prone settlement in Western Turkey 显示文摘 | Hasancebi Nilsun Ulusay Resat | 2006 | Engineering Geology2006，87，2： | 1 |
| 15 | Heavy metal cation retention by unconventional sorbents(red muds and fly ashes)显示文摘 | Resat Apak Esma Tutem Mehmet Hugul Julide Hizal | 1998 | Water Research1998，32，2： | 1 |
| 16 | Note on a New Construction of Kantorovich Form q-Bernstein Operators Related to Shape Parameter λ显示文摘The main purpose of this paper is to introduce some approximation properties of a Kantorovich kind q-Bernstein operators related to B′ezier basis functions with shape parameterλ∈[−1,1].Firstly,we compute some basic results such as moments and central moments,and derive the Korovkin type approximation theorem for these operators.Next,we estimate the order of convergence in terms of the usual modulus of continuity,for the functions belong to Lipschitz-type class and Peetre’s K-functional,respectively.Lastly,with the aid of Maple software,we present the comparison of the convergence of these newly defined operators to the certain function with some graphical illustrations and error estimation table. | Qingbo Cai Resat Aslan | 2022 | Computer Modeling in Engineering & Sciences2022，，3： | 1 |
| 17 | Probability-weighted dynamic Monte Carlo method for reaction kinetics simulations 显示文摘 | RESAT H WILEY H S DIXON D A | 2001 | Journal of Physical Chemistry B2001，105，11： | 1 |
| 18 | Quantum Yields and Relative Photonic Efficiencies of Substituted 1,3- Dihydroxy Benzenes 显示文摘 | OKTE A N RESAT M S INEL Y | 2000 | Photochemistry and Photobiology A : Chemistry2000，134，1： | 1 |
| 19 | Monte Carlo simulation of single-cell irradi- ation by an electron microheam显示文摘 | MILLER J H RESAT M S METTING N F | 2000 | Radiation Environment Biophysics2000，39，2： | 1 |
| 20 | Satellite attitude control by integrator back-stepping with internal stabilization 显示文摘 | Resat 0 D Erol K | 2008 | International Journal ofAircraft Engineering and Aerospace Technology2008，80，1： | 1 |
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