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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | The Lancet2011，，9785： | 6 |
| 3 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | The Lancet2011，，9785： | 2 |
| 4 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | 2011 (9785)2011，，9785： | 2 |
| 5 | Equilibrium in Sealed High Bid Auctions显示文摘 | MASKIN E RILEY J | 2000 | Review of Economic Studies2000，67，3： | 1 |
| 6 | PD-1 signaling in primary T cells显示文摘 | Riley J L | 2009 | Immunol Rev2009，229，： | 1 |
| 7 | 2-D multiple reflections显示文摘 | Riley D C Claerbout J F | 1976 | Geophysics1976，41，4： | 1 |
| 8 | Observation of the autumn migration of the rice leaf roller Cnahalocrocis medinalis (Lepidoptera: Pyralidae) and other moths in eastern china 显示文摘 | Riley J R Reynolds D R Smith A D | 1995 | Bull Ent Res1995，85，： | 1 |
| 9 | Lipoxygenase and hydroperoxide lyase activity in ripening tomato fruit显示文摘 | RILEY J C M WILLEMOT C THOMPSON J E | 1996 | Postharvest Biol Technol1996，7，12： | 1 |
| 10 | Radiofrequency volumetrictissue reduction of the palate in subjects with sleep-disorderedbreathing显示文摘 | Powell N B Riley R W Troell R J | 1998 | Chest1998，113，： | 1 |
| 11 | Pal- atability of beef from steer and young bull car-casses as influenced by electrical stimulation, subcutaneous fat thickness and marbling 显示文摘 | RILEY R R SAVELL J W MURPHEY C E | 1983 | Journal of Animal Science1983，56，3： | 1 |
| 12 | Salvinorin Aproduces cerebrovasodilation through activation of nitricsensitive potassium channel显示文摘 | SU D RILEY J KIESSLING W J | 2011 | Anesthesiology2011，114，2： | 1 |
| 13 | Pathogenesis of virulent Newcastle disease in chickens显示文摘 | Cheville N F Riley J Ritchie A E | 1972 | J Am Vet Med Assoc1972，，： | 1 |
| 14 | Walking with labor epidural analgesia:the impact of bupivacaine concentration and a lidocaine-epinephrine test dose 显示文摘 | Cohen S E Yeh J Y Riley E T | 2000 | Anesthesiology2000，92，： | 1 |
| 15 | Collecting and analyzing cord blood gases 显示文摘 | Riley R J Johnson JWC | 1993 | Clin Obstet Gynecol1993，36，1： | 1 |
| 16 | Comparison of postoperative pain between laser assisted uvulopalatoplasty,uvulopalatopharyngoplasty and radiofrequency volumetric tissue reduction of the palate显示文摘 | Troell T J Powell N B Riley T W | 2000 | Otolaryngol Head Neck Surg2000，122，： | 1 |
| 17 | Cobalt requirement for nodule development and function in Lupinus angustifolius 显示文摘 | Riley B T Ditworth M J | 1985 | New Physiologhist1985，100，： | 1 |
| 18 | CIMO Ligand (CD154) triggers ashort-term CD4+ T cell aetivition response that results in secretion of immunomodulatory cytokines and apoptosis显示文摘 | Blair P J Riley J L Harlan D M | 2000 | J Exp Med2000，191，4： | 1 |
| 19 | Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight显示文摘 | Riley D A Bain J L Thompson J L | 2000 | J Appl Physiol2000，88，2： | 1 |
| 20 | Composite electrolytes from self-assembled colloidal networks显示文摘 | Walls H J Riley M W Fedkiw P S | 2003 | Electrochimica Acta2003，48，： | 1 |
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