|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Influence of valvular insufficiency and recurrent airway obstruction on haemody- namics and therapy in warmblood horses with atrial fibrilla- tion显示文摘 | Gehlen H Bubeck K Rohn K | 2008 | Res Vet Sci2008，85，2： | 1 |
| 2 | Pulmonary artery wedge pressure during treadmill exercise in wannblood horses with atrial fibrillation显示文摘 | Gehlen H Bubeck K Rohn K | 2006 | Res Vet Sci2006，81，1： | 1 |
| 3 | A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis显示文摘 | Rohn T T Ivins K J Bahr B A | 2000 | J Neurochem2000，74，6： | 1 |
| 4 | Nanopartieles and Pop-off Technique for Eleetron Mieroseopy: A Known Tech- nique for a New Purpose显示文摘 | Lehmbeeker A Pdttinghausen S Rohn K | 2014 | Toxieol Pathol2014，42，6： | 1 |
| 5 | Amplification of an invA gene sequence of salmonella typhimurium by polymerase chain react ion as a specific method of detect ion of salmonella 显示文摘 | Rohn K Grandis SA De Clarke RC et ai | 1992 | Mol Cell probes1992，，6： | 1 |
| 6 | A Multipathogen Bile Sample-based PCR Assay Can Guide Empirical Antimicrobial Strategies in Cholestatic Liver Diseases显示文摘Background and objectives:Polymerase chain reaction(PCR)techniques provide rapid detection of pathogens.This pilot study evaluated the diagnostic utility and clinical impact of multiplex real-time PCR(mRT-PCR,SeptiFast)vs.conventional microbial culture(CMC)in bile samples of patients with chronic cholestatic liver diseases(cCLDs),endoscopic retrograde cholangio-pancreatography(ERCP),and peri-interventional-antimicrobial-prophylaxis(pAP).Methods:We prospectively collected bile samples from 26 patients for microbiological analysis by CMC and mRT-PCR.Concordance of the results of both methods was determined by Krippendorff's alpha(α)for inter-rater reliability and the Jaccard index of similarity.Results:mRT-PCR_(bile)and CMC_(bile)results were concordant for only Candida albicans(α=0.8406;Jaccard index=0.8181).mRT-PCR_(bile)detected pathogens in 8/8 cases(100%),CMC_(bile)in 7/8(87.5%),and CMCblood in 5/8(62.5%)with clinical signs of infection.mRTPCR_(bile),CMC_(bile),and CMCblood had identical detection results in 3/8(37.5%)with clinical signs of infection(two Klebsiella spp.and one Enterococcus faecium).The total pathogen count was significantly higher with mRT-PCR_(bile)than with CMC_(bile)(62 vs.31;χ^(2)=30.031,p<0.001).However,pathogens detected by mRT-PCR_(bile)were more often susceptible to pAP according to the patient infection/colonization history(PI/CH)and surveillance data for antibiotic resistance in our clinic(DARC).Pathogens identified by mRT-PC_(Rbile)and resistant to pAP by PI/CH and DARC were likely to be clinically relevant.Conclusions:mRT-PCR in conjunction with CMCs for bile analysis increased diagnostic sensitivity and may benefit infection management in patients with cholestatic diseases.Implementation of mRT-PCR in a bile sample-based diagnostic routine can support more rapid and targeted use of antimicrobial agents in cCLD-patients undergoing ERCP and reduce the rate/length of unnecessary administration of broad-spectrum antibiotics. | Michael Jahn Mustafa KÖzçürümez Sebastian Dolff Hana Rohn Dominik Heider Alexander Dechêne Ali Canbay Peter M.Rath Antonios Katsounas | 2022 | Journal of Clinical and Translational Hepatology2022，10，5： | 1 |
| 7 | Distinct cell tropism of canine distemper virus strains to adult olfactory ensheathing cells and Schwann cells in vitro显示文摘 | Techangamsuwan S Haas L Rohn K | | 0，，1： | 1 |
| 8 | Collaborative Consumption: Towardsa Resource-Saving Consumption Culture 显示文摘 | Leismann K Schm itt M Rohn H | 2013 | R esources2013，2，： | 1 |
| 9 | Flavo- nols,hetacyanins content and antioxidant activity of cactus Opuntia macrorhiza fruits显示文摘 | Moussa-Ayoub T E EI-Samahy S K Rohn S | | 0，，07： | 1 |
| 10 | Reactions of chlorogenic acid and quercetin with a soy protein isolate - influence on the in vivo food protein quality in rats显示文摘 | Rohn S Petzke K J Rawel H M | 2006 | Molecular Nutrition and Food Research2006，50，： | 1 |
| 11 | Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA显示文摘 | Leliveld S R Dame R T Mommaas M A Koerten H K Wyman C Danen-van Oorschot A A Rohn J L Noteborn M H Abrahams J P | 2003 | Nucleic Acids Res2003，31，16： | 1 |
| 12 | Influences of increased levels ofbiotin, zinc or mannanoligosaccharides in the diet on foot pad dermatitis ingrowing turkeys housed on dry and wet litter 显示文摘 | YoussefI M I Beineke A Rohn K | 2012 | J Anim Physiol Anim Nutr(Berl)2012，96，： | 1 |
| 13 | Chlorogenic acid moderately decreases the quality of whey proteins in rats显示文摘 | PETZKE K J SCHUPPE S ROHN S | 2005 | Journal of Agricultural and Food Chemistry2005，53，9： | 1 |
| 14 | Investigation of the flow at the exit of an unshrouded centrifugal impeller and comparison with the 'classical' jet-wake theory 显示文摘 | ROHNE K H BANZHAF M | 1991 | ASME Journal of Turbomachinery1991，113，4： | 1 |
| 15 | On the role of monoclonal antibody affinity in mediating protection against autoimmune inflammatory diseases显示文摘 | Dallenbaeh K Rohn T Beerli R | 2009 | Swiss Medical Weekly2009，139，910： | 1 |
| 16 | Identifiication and characterization of penton base and pⅧ protein of egg drop syndrome virus 显示文摘 | Rohn K Prusas C Monreal G | 1997 | VirusRes1997，47，1： | 1 |
| 17 | Brush Plated ZnS Films and Their Properties显示文摘 | Murali K R Dhanemozhi C A Rohn R | 2008 | Journal of Alloys and Compounds2008，464，12： | 1 |
| 18 | Investigation of the flow at the exit of an unshrouded centrifugal impeller and comparison with the 'classical' jet-wake theory显示文摘 | Rohne K H Banzhaf M | 1991 | ASME Journal of Turbomachinery1991，113，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员