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| 1 | Elucidation and biological activities of a new polysaccharide from cultured Cordyceps militaris显示文摘 | Yongshuai Jing Xinlu Cui Zhiyan Chen Lijiao Huang Liyan Song Ting Liu Wenjie Lv Rongmin Yu | 2014 | Carbohydrate Polymers2014，，： | 1 |
| 2 | Noninvasive Low-Frequency Pulsed Focused Ultrasound Therapy for Rheumatoid Arthritis in Mice显示文摘Rheumatoid arthritis(RA)is a common autoimmune disease characterized by chronic and progressive inflammation of the synovium.Focused ultrasound therapy is an increasingly attractive alternative for treating RA owing to its noninvasiveness;however,it remains unclear which immune subsets respond to ultrasound stimulation.In this study,we showed that spleen-targeted low-frequency pulsed focused ultrasound(LFPFU)effectively improved the severity of arthritis in an arthritis mouse model established in DBA/1J mice.Additionally,we performed in-depth immune profiling of spleen samples from RA mice,RA mice that underwent ultrasound therapy,and healthy controls using mass cytometry along with extensive antibody panels and identified the immune composition of 14 cell populations,including CD4^(+)/CD8^(+)T cells,B cells,natural killer cells,and dendritic cells.Moreover,multidimensional analysis according to cell-surface markers and phenotypes helped in identifying 4 and 5 cell subpopulations among T and myeloid cells,respectively,with 6 T cell subsets and 3 myeloid cell subsets responsive to ultrasound therapy among the 3 groups.Of these cell subsets,CD8^(+)T cell subsets showed a unique response to ultrasound stimulation in RA mice.Specifically,CD8^(+)T cells show a noticeable correlation with the degree of arthritis progression and could serve as an indicator for spleen-focused ultrasound-based therapy.Furthermore,single-cell RNA sequencing of spleen cells revealed the importance of T,B,and myeloid cell populations in the anti-inflammatory pathway.These results elucidated the unique cell subsets and transcriptome of splenic cells responsive to LFPFU and demonstrated the potential of spleen-focused ultrasound stimulation in the treatment of inflammatory diseases. | Xuqiao Hu Fei Li Jieying Zeng Zhenru Zhou Zhaoyang Wang Jing Chen Dongyan Cao Yifan Hong Laixin Huang Yongsheng Chen Jinfeng Xu Fajn Dong Rongmin Yu Harong Zhen | 2023 | Research2023，，3： | 0 |
| 3 | RS-SVM Machine Learning Approach Driven by Case Data for Selecting Urban Drainage Network Restoration Scheme显示文摘Urban drainage pipe network is the backbone of urban drainage,flood control and water pollution prevention,and is also an essential symbol to measure the level of urban modernization.A large number of underground drainage pipe networks in aged urban areas have been laid for a long time and have reached or practically reached the service age.The repair of drainage pipe networks has attracted extensive attention from all walks of life.Since the Ministry of ecological environment and the national development and Reform Commission jointly issued the action plan for the Yangtze River Protection and restoration in 2019,various provinces in the Yangtze River Basin,such as Anhui,Jiangxi and Hunan,have extensively carried out PPp projects for urban pipeline restoration,in order to improve the quality and efficiency of sewage treatment.Based on the management practice of urban pipe network restoration project in Wuhu City,Anhui Province,this paper analyzes the problems of lengthy construction period and repeated operation caused by the mismatch between the design schedule of the restoration scheme and the construction schedule of the pipe network restoration in the existing project management mode,and proposes a model of urban drainage pipe network restoration scheme selection based on the improved support vector machine.The validity and feasibility of the model are analyzed and verified by collecting the data in the project practice.The research results show that the model has a favorable effect on the selection of urban drainage pipeline restoration schemes,and its accuracy can reach 90%.The research results can provide method guidance and technical support for the rapid decision-making of urban drainage pipeline restoration projects. | Li Jiang Zheng Geng Dongxiao Gu Shuai Guo Rongmin Huang Haoke Cheng Kaixuan Zhu | 2023 | Data Intelligence2023，5，2： | 0 |
| 4 | Experiment on the Effect of Sediment Concentration on Flow Structure显示文摘The paper studies on the sediment-laden flow by using MicroADV.Laboratory calibration has been conducted to determine the relationship between backscattered signal strength and sediment concentration. Based on the experimental data,the interactions between sediment and fluid in open channel flow are investi- gated.The experiment shows that there exist inner relation between sediment concentration and turbulence, and the relationship is distinctry related to the diameter of particle as well as the flow co... | Chen, Li Wu, Menwu Deng, Xiaoli Huang, Rongmin | 2005 | 四川大学学报(工程科学版)2005，37，S1： | 0 |
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