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| 1 | A Systemic Review of Autologous Fat Grafting Survival Rate and Related Severe Complications显示文摘 | Nan-Ze Yu Jiu-Zuo Huang Hao Zhang Yang Wang Xiao-Jun Wang Ru Zhao Ming Bai Xiao Long | 2015 | Chinese Medical Journal2015，，9： | 12 |
| 2 | Therapeutic efficacy and safety of various botulinum toxin A doses and concentrations in spastic foot after stroke: a randomized controlled trial显示文摘No recommended guidelines currently exist for the therapeutic concentration or dose of botulinum toxin type A(BTXA) injected into the muscle to treat limb spasticity. Therefore, in this randomized controlled trial, we explored the safety and efficacy of two concentrations and two doses of BTXA in the treatment of spastic foot after stroke to optimize this treatment in these patients. Eligible patients(n = 104) were randomized into four groups. The triceps surae and tibialis posterior on the affected side were injected with BTXA at one of two doses(200 U or 400 U) and two concentrations(50 U/m L or 100 U/m L). The following assessments were conducted before as well as 4 days and 1, 2, 4, and 12 weeks after treatment: spasticity, assessed using the modified Ashworth scale; basic functional mobility, assessed using a timed up and go test; pace, assessed using a 10-meter timed walking test; and the ability to walk, assessed using Holden's graded scale and a visual analog scale. The reported results are based on the 89 patients that completed the study. We found significant differences for the two doses and concentrations of BTXA to improve the ability of patients to walk independently, with the high-dose/low-concentration combination providing the best effect. Onset and duration of the ameliorating effects of BTXA were 4–7 days and 12 weeks, respectively. Thus, BTXA effectively treated foot spasms after stroke at an optimal dose of 400 U and concentration of 50 U/m L. | Jiang Li Ru Zhang Bo-li Cui Yong-xiang Zhang Guang-tao Bai Si-shan Gao Wen-jian Li | 2017 | Neural Regeneration Research2017，12，9： | 7 |
| 3 | Design,Synthesis and in vitro Evaluation of a New Class of Novel Cyclooxygenase-2 Inhibitors:3,4-diaryl-3-pyrrolin-2-ones显示文摘design, synthesis and in vivo evaluation of a new class of COX-2 inhibitors 3, 4-diaryl-3-pyrrolin-2-ones are reported. | Ai Ping BAI, Zong Ru GUO*, Wen Hui HU, Fang SHEN, Gui Fang CHENG Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050 | 2001 | Chinese Chemical Letters2001，12，9： | 7 |
| 4 | A new tool for comprehensive geriatric assessment in elderly patients with acute myeloid leukemia:a pilot study from China显示文摘Background:Acute myeloid leukemia(AML)is a common type of hematological malignancy in elderly people.Geriatricians developed comprehensive geriatric assessment(CGA)methods for elderly patients;however,the tools used for CGA in AML are not uniform.Thus,we aimed to validate the instrumental activities of daily living(IADL)scales,age,comorbidities(Charlson Comorbidity Index),and albumin(IACA)index,which is a new tool for CGA,in elderly patients with AML.Methods:Patients aged>60 years who had been diagnosed with AML were screened for eligibility.Among the IACA low-,intermediate-,and high-risk groups,continuous variables were compared using the Mann-Whitney U test,and categorical variables were compared using/2 and Fisher exact tests.In addition,probabilities of overall survival(OS)were estimated using the Kaplan-Meier method.Results:A total of 21,34,and 6 patients were categorized into IACA low-risk(0 point),intermediate-risk(1-2 points),and high-risk(>3 points)groups,respectively.The rates of relapse/progression-related mortality were 23.8%,58.8%,and 100.0%in the IACA low-,intermediate-,and high-risk groups,respectively(χ^2=12.81,P<0.001).The 2-year probabilities of OS were 47.7%(95%confidence interval[CI]22.8%-72.6%)and 20.2%(95%CI 5.9%-34.5%)in the IACA low-and intermediate-risk groups,respectively(χ^2=5.99,P=0.014),which were significantly higher than those in the high-risk group(low-risk[47.7%(95%CI 22.8%-72.6%)]vs.high-risk[0],/=20.80,P<0.001;intermediate-risk[20.2%(95%CI 5.9%-34.5%)]vs.high-risk[0],χ^2=7.56,P=0.006;respectively).In the IACA low-risk group,the 2-year probability of OS in patients receiving induction chemotherapy(50.8%[95%CI 24.1%-77.5%])was significantly higher than that in those receiving best supportive care(0,χ^2=25.74,P<0.001).Conclusion:We suggest that the IACA index might be a simple and effective tool for comprehensive geriatric assessment in elderly AML patients. | Chun-Li Zhang Ru Feng Jiang-Tao Li Ting Wang Jie-Fei Bai Hui Liu | 2020 | Chinese Medical Journal2020，，4： | 5 |
| 5 | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase Ⅰ and topoisomerase Ⅱ显示文摘OBJECTIVE The aim of this study is to investigate the inhibitory effects of lapachol on rat C6 glioma both in vitro and in vivo,as well as the potential mechanisms.METHODS First,the model of C6 glioma in Wistar rats was established and verified by hemotoxylin and eosin staining,immunohistochemical staining and magnetic resonance imaging(MRI).Then different doses of lapachol were gavaged and tumor volumes of the C6 glioma were detected by MRI.The effects of lapachol on C6 cell proliferation,apoptosis and DNA damage were detected by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium(MTS)/phen-azinemethosulfate(PMS)assay,Hoechst33358 staining,AnnexinⅤ-FITC/PI staining,and comet assay.Effects of lapachol on topoisomeraseⅠ(TOPⅠ)and topoisomeraseⅡ(TOPⅡ)activities were detected by TOPⅠand TOPⅡmediated supercoiled p BR322 DNA relaxation assay.Molecular docking was used to predict the interaction of lapachol-TOPⅠand lapachol-TOPⅡ.TOP I and TOPⅡexpression levels in C6 cells were determined by Enzymelinked immunosorbent assay kits and real-time polymerase chain reaction(RT-PCR).RESULTS The rat C6 glioma model was successfully established.High dose lapachol showed significant inhibitory effect on the C6 glioma in Wistar rats(P<0.05).MTS/PMS assay,Hoechst 33258 staining,AnnexinⅤ-FITC/PI staining,and comet assay showed that lapachol could inhibit proliferation,induce apoptosis and DNA damage of C6 cells in dose dependent manners.Lapachol could inhibit the activities of both TOPⅠandⅡ.Molecular docking showed that lapachol-TOPⅠshowed relatively stronger interaction than that of lapachol-TOPⅡ.Enzyme-linked immunosorbent assay and RT-PCR showed that lapachol could inhibit TOPⅡexpression levels,but not TOPⅠexpression levels.CONCLUSION These results showed that lapachol could significantly inhibit C6 glioma both in vivo and in vitro,which might be related with inhibiting TOPⅠand TOPⅡactivities,as wel as TOPⅡexpression. | XU Huan-li CHEN Qun-ying WANG Hong XU Ping-xiang YUAN Ru LI Xiao-rong BAI Lu XUE Ming | 2016 | 中国药理学与毒理学杂志2016，30，10： | 3 |
| 6 | Three-year Follow-up on the Safety and Effectiveness of Rituximab Plus Chemotherapy as First-Line Treatment of Diffuse Large B-Cell Lymphoma and Follicular Lymphoma in Real-World Clinical Settings in China: A Prospective, Multicenter, Noninterventional Study显示文摘 | Jian-Qiu WU Yong-Ping Song Li-Ping Su Ming-Zhi Zhang Wei Li Yu Hu Xiao-Hong Zhang Yu-Huan Gao Zuo-Xing Niu Ru Feng Wei Wang Jie-Wen Peng Xiao-Lin Li Xue-Nong Ouyang Chang-Ping Wu Wei-Jing Zhang Yun Zeng Zhen Xiao Ying-Min Liang Yong-Zhi Zhuang Ji-Shi Wang Zi-Min Sun Hai Bai Tong-Jian Cui Ji-Feng Feng | 2018 | Chinese Medical Journal2018，，15： | 3 |
| 7 | Effect of sintering temperature on the electrolysis of TiO_2显示文摘The effects of sintering temperature on the microstructure and the conductivity of TiO 2 cathodes were studied by examining the phase composition, microstructure, and element contents of the sintered cathodes and the cathodic products using X-ray diffraction and scan-ning electronic microscopy-energy dispersive spectrometry. The oxygen vacancy, conductivity, average pore diameter, and specific surface area of the sintered cathodes were detected by X-ray photoelectron spectroscopy, four-point probe, and ASPA 2010. The results showed that TiO 2 phase transformations occurred, and oxygen vacancies formed with the increase of sintering temperature. The cathodic conductivity improved, but the average pore diameter and the effective response area of the TiO 2 cathode were reduced when the sintering temperature increased. These phenomena could weaken the contact between reaction ions and electrons and also had the same effect on the cathodes and the molten salt. Moreover, they were disadvantageous to ion migration, so a lower sintering temperature was favorable for the microstructure of electrolysis. Consequently, the cathodic conductivity may be improved, but the microstructure became compact with the increase of sintering temperature. The cathodic products at different temperatures indicated that the cathodic conductivity was more important for electrolysis. | Ze-quan Li Li-yue Ru Cheng-guang Bai Na Zhang Hai-hua Wang | 2012 | International Journal of Minerals,Metallurgy and Materials2012，19，7： | 2 |
| 8 | Environmental Monitoring of A Laboratory for New Coronavirus Nucleic Acid Testing显示文摘The coronavirus disease 2019(COVID-19) is an infection of the respiratory tract which first broke out in Wuhan, China, in December 2019. The etiologic agent of this disease was identified as a betacoronavirus related to severe acute respiratory syndrome coronavirus(SARS-CoV). Thus, the International Committee on Virus Classification named the new coronavirus severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)[1]. | NING Pei Yong YU Ai Ping WANG Yuan GUO Li Ru SHAN Dan KONG Mei YU Ling Qi LYU Li Kun ZOU Ming SU Xu FEI Chun Nan ZHOU Yu Hui WANG Bai Qi | 2020 | Biomedical and Environmental Sciences2020，33，10： | 2 |
| 9 | Two new isoflavonoids from the rhizomes of Belamcanda chinensis显示文摘Two new isoflavonoids, 6-methoxy-5,7,8,4’-tetrahydryoxyisoflavone (1) and 4’-methoxy -5,6-dihydroxyisoflavone-7-O-β-D-glucopyranoside (2), were isolated from the rhizomes of Belamcanda chinensis (L.) DC. Their structures were elucidated by extensive spectroscopic evidence including ID NMR, 2D NMR, MS and IR spectra. | Zhi Jun Song Fan Luo Yan Zhou Bin Ru Bai Shu Lin Peng Li Sheng Ding | 2007 | Chinese Chemical Letters2007，18，6： | 2 |
| 10 | Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese显示文摘Objective To study the relation between serum calcium level and elevated BaPWV in Chinese subjects.Methods The relation between serum calcium level and elevated BaPWV was studied in 9 615subjects.The mean value of left and right BaPWV was analyzed.BaPWV was defined as high when it was?1 752.5 cm/s(the upper quartile)either side.Results The BaPWV and its elevated percentage progressively increased across the quartiles of the serum calcium level(P<0.05).The prevalence of elevated BaPWV was significantly higher in subjects of the second,third and highest quartiles than in those of the lowest quartile(26.9%,28.4%,and 33.2%vs23.7%,P=0.0116,P=0.0004,and P<0.0001).Logistic regression analysis revealed that the risk of elevated BaPWV was 1.32-fold higher in subjects of the highest quartile than in those of the lowest quartile(OR=1.32,95%CI:1.08-1.60).Conclusion The elevated serum calcium level is related to an elevated BaPWV and a higher risk of arterial stiffness,independent of conventional risk factors,in middle-aged and elderly Chinese subjects. | DENG Xin Ru ZHANG Yin Fei WANG Tian Ge XU Bai Hui SUN Ji Chao ZHAO Lie Bin XU Min CHEN Yu Hong WANG Wei Qing BI Yu Fang LU Jie Li | 2014 | Biomedical and Environmental Sciences2014，27，8： | 2 |
| 11 | Experimental study on ion-flow fields inside greenhouse models underneath the DC test wire显示文摘 | Bai Ru Cui Xiang Lu Tiebing | 2013 | IEEE Transactions on Power Delivery2013，28，4： | 1 |
| 12 | Two New Acetyl Cimicifugosides from the Rhizomes of Cimicifuga Racemosa显示文摘Two new acetyl cimicifugosides were isolated from the rhizomes of Cimicifuga racemosa. Their structures were elucidated as 2’-O-acetyl cimicifugoside H-1 1 and 3’-O-acetyl cimicifugoside H-1 2 by the spectroscopic evidence and chemical methods. | Chun DAN Rui WANG Shu Lin PENG Bing Ru BAI Li Sheng DING | 2006 | Chinese Chemical Letters2006，17，3： | 1 |
| 13 | Role of secondary structures in the gelation of porcine myosin at different pH values 显示文摘 | Ru Liu Si - ming Zhao Shan - bai Xiong etal | 2008 | Meat Science2008，，14： | 1 |
| 14 | Enhanced laser-based magneto-optic imaging system for nondestructive evaluation applications显示文摘 | Yu hua Cheng Yi ruing Deng Li bing Bai | 2013 | IEEE Transction on Instrumentaion and Measurement2013，62，5： | 1 |
| 15 | Averaging analysis for discrete time and sampled data adaptive system显示文摘 | Bai E Ru L Sastry S | 1988 | IEEE trans on circuits system1988，35，2： | 1 |
| 16 | 查看详情显示文摘 | Ma X Wang M Li G Chen H.and Bai Ru | | 0，，： | 1 |
| 17 | Deflagra tion to detonation transition in nitromethane mist/ aluminum dust/ air mixtures显示文摘 | LIU Qing ruing BAI Chun-hua JIANG Li | 2010 | Combustion and Flame2010，1，157： | 1 |
| 18 | The roles of foam ceramics in suppression of gas explosion over - pressure and quenching of flame propagation显示文摘 | NIE Bai - sheng HE Xue - qiu ZI-IANG Ru - ruing | 2011 | Journal of Haz- ardous Materials2011，192，2： | 1 |
| 19 | Non - ionotropic cross - talk betwenn AMPA and NMDA receptors in rodent hippocampal neurones 显示文摘 | Bai D Muller RU Roder JC | 2002 | J Physiol2002，543，1： | 1 |
| 20 | MXenes nanocomposites for energy storage and conversion显示文摘The development of two-dimensional(2 D)high-performance electrode materials is the key to new advances in the fields of energy storage and conversion.As a novel family of 2 D layered materials,MXenes possess distinct structural,electronic and chemical properties that enable vast application potential in many fields,including batteries,supercapacitor and catalysis.However,MXene layers are easily formed by stacking together,which significantly reduces the specific surface area,hinders the transmission of ions,and restricts other functional materials on the surface,thereby reducing performance.In addition,due to the inherent defects of a single electrode material,electrodes or catalysts made of single-phase MXene may not meet specific practical application requirements.MXenes nanocomposites materials based on enhanced electrochemical performance through nanoengineering technology and surface modification for morphological control are highly sought after to solve these challenges.This review aims to present recent advances in these emerging MXene nanocomposites for energy storage and conversion applications such as batteries,supercapacitors and catalytic reactions.We also introduced some of the challenges and opportunities in this rapidly developing field. | Zi-Ming Qiu Yang Bai Yi-Dan Gao Chun-Li Liu Yue Ru Ye-Can Pi Yi-Zhou Zhang Yong-Song Luo Huan Pang | 2022 | Rare Metals2022，41，4： | 1 |
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