|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of double platinum agents, combination of miriplatintransarterial oily chemoembolization and cisplatinhepatic arterial infusion chemotherapy, in patients with hepatocellular carcinoma: Report of two cases显示文摘Hepatocellular carcinoma(HCC) is one of the most common cancers and the third highest cause of cancerassociated mortality worldwide. The treatment of HCC is complicated by its variable biological behavior and the frequent coexistence of chronic liver disease, particularly cirrhosis. To date, multiple treatment modalities have been developed according to the stage of the tumor and the hepatic functional reserve, including transarterial treatments such as transarterial chemoembolization, transarterial oily chemoembolization(TOCE), and hepatic arterial infusion chemotherapy(HAIC). We conducted a phase I and II study of the combination therapy with double platinum agents, miriplatin and cisplatin, and confirmed its safety and efficacy. Here, we describe two cases of unresectable HCC who were successfully treated by miriplatin-TOCE/cisplatin-HAIC combination therapy, resulting in complete responses with no significant adverse events. This report will provide that the combination therapy can be the therapeutic option for HCC patients in the advanced stage. | Kohei Ogawa Kenya Kamimura Yukari Watanabe Yosuke Motai Daisuke Kumaki Ryoya Seki Akira Sakamaki Satoshi Abe Hirokazu Kawai Takeshi Suda Satoshi Yamagiwa Shuji Terai | 2017 | World Journal of Clinical Cases2017，5，6： | 4 |
| 2 | Mucosal necrosis of the small intestine in myopathy,encephalopathy,lactic acidosis,and stroke-like episodes syndrome显示文摘This report presents a case of massive mucosal necrosis of the small intestine in a patient with mitochondrial myopathy,encephalopathy,lactic acidosis,and stroke-like episodes(MELAS),which particularly affects the brain,nervous system and muscles.A 45-year-old Japanese female,with an established diagnosis of MELAS,presented with vomiting.Computed tomography showed portomesenteric venous gas and pneumatosis intestinalis.She underwent a resection of the small intestine.A microscopic study showed necrosis of the mucosa and vacuolar degeneration of smooth muscle cells in the arterial wall.Immunohistochemistry showed anti-mitochondrial antibody to be highly expressed in the crypts adjacent the necrotic mucosa.The microscopic and immunohistochemical findings suggested the presence of a large number of abnormal mitochondria in MELAS to be closely linked to mucosal necrosis of the small intestine. | Keita Fukuyama Yasuhide Ishikawa Tetsuro Ogino Hidenobu Inoue Ryoya Yamaoka Tetsuro Hirose Tomohiko Nishihira | 2012 | World Journal of Gastroenterology2012，18，41： | 2 |
| 3 | Wavelet analysis of envelope soliton interaction显示文摘 | HORIHATA S RYOYA S | | 0，，04： | 1 |
| 4 | Calcitonin gene related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rat显示文摘 | Ryoya O Satoh M Fujii N | 1987 | Brain Research1987，403，： | 1 |
| 5 | Variations in the FTO gene are associated with severe obesity in the Japanese显示文摘 | Kikuko Hotta Yoshio Nakata Tomoaki Matsuo Seika Kamohara Kazuaki Kotani Ryoya Komatsu Naoto Itoh Ikuo Mineo Jun Wada Hiroaki Masuzaki Masato Yoneda Atsushi Nakajima Shigeru Miyazaki Katsuto Tokunaga Manabu Kawamoto Tohru Funahashi Kazuyuki Hamaguchi Kenta | 2008 | Journal of Human Genetics2008，，6： | 1 |
| 6 | Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats显示文摘 | Masamichi S | 1987 | Brain Research1987，403，： | 1 |
| 7 | Calcitonin gene related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rat显示文摘 | Ryoya O Satoh M Fujii N | 1987 | Brain Researeh1987，403，： | 1 |
| 8 | Calcitonin gene related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rat显示文摘 | SATOH M FUJII N | 1987 | Brain Research1987，403，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员