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| 1 | Oocyte Cryopreservation in Human Assited Reproduction显示文摘Embryo cryopreservation(CP) has became a very important part of the clinical use of in vitro fertilization. Oocyte CP offers more advantages compared with embryo freezing with regard to less ethical, legal and moral problems. However, the efficiency of this procedure is still low, which prevents its clinical application in wide range. The aim of our paper is to review the basic principles, technical and safety aspects and current status of oocyte cryopreservation in human assisted reproduction. | J Konc S Cseh E Varga R Kriston K Kanyó | 2006 | Journal of Reproduction and Contraception2006，17，2： | 7 |
| 2 | Intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease显示文摘AIM:To investigate intestinal alkaline phosphatase(iAP) in the intestinal mucosa of children with inflammatory bowel disease(IBD).METHODS:Colonic biopsy samples were taken from 15 newly diagnosed IBD patients and from 10 healthy controls.In IBD patients,specimens were obtainedboth from inflamed and non-inflamed areas.The iAP mRNA and protein expression was determined by reverse transcription-polymerase chain reaction and Western blotting analysis,respectively.Tissue localization of iAP and Toll-like receptor(TLR) 4 was investigated by immunofluorescent staining.RESULTS:The iAP protein level in the inflamed mucosa of children with Crohn's disease(CD) and ulcerative colitis(UC) was significantly decreased when compared with controls(both P < 0.05).Similarly,we found a significantly decreased level of iAP protein in the inflamed mucosa in CD compared with non-inflamed mucosa in CD(P < 0.05).In addition,the iAP protein level in inflamed colonic mucosa in patients with UC was decreased compared with non-inflamed mucosa in patients with CD(P < 0.05).iAP protein levels in the non-inflamed mucosa of patients with CD were similar to controls.iAP mRNA expression in inflamed colonic mucosa of children with CD and UC was not significantly different from that in non-inflamed colonic mucosa with CD.Expression of iAP mRNA in patients with noninflamed mucosa and in controls were similar.Co-localization of iAP with TLR4 showed intense staining with a dotted-like pattern.iAP was present in the inflamed and non-inflamed mucosa of patients with CD,UC,and in control biopsy specimens,irrespective of whether it was present in the terminal ileum or in the colon.However,the fluorescent signal of TLR4 was more pronounced in the colon compared with the terminal ileum in all groups studied.CONCLUSION:Lower than normal iAP protein levels in inflamed mucosa of IBD patients may indicate a role for iAP in inflammatory lesions in IBD.Based on our results,administration of exogenous iAP enzyme to patients with the active form of IBD may be a therapeutic option. | Kriszta Molnár dám Vannay Beáta Szebeni Nóra Fanni Bánki Erna Sziksz ron Cseh Hajnalka Gyrffy Péter László Lakatos Mária Papp András Arató Gábor Veres | 2012 | World Journal of Gastroenterology2012，18，25： | 5 |
| 3 | Characteristics of allergic colitis in breast-fed infants in the absence of cow's milk allergy显示文摘AIM: To investigate the characteristics of mucosal le-sions and their relation to laboratory data and long-term follow up in breast-fed infants with allergic colitis. METHODS: In this study 31 breast-fed infants were prospectively evaluated (mean age, 17.4 wk) whose rectal bleeding had not ceased after a maternal elimi-nation diet for cow's milk. Thirty-four age-matched and breast-fed infants (mean age, 16.9 wk) with no rectal bleeding were enrolled for laboratory testing as con-trols. Laboratory findings, colonoscopic and histological characteristics were prospectively evaluated in infants with rectal bleeding. Long-term follow-up with differ-ent nutritional regimes (L-amino-acid based formula or breastfeeding) was also included. RESULTS: Iron deficiency, peripheral eosinophilia andthrombocytosis were significantly higher in patients with allergic colitis in comparison to controls (8.4±3.2 μmol/L vs 13.7±4.7 μmol/L, P<0.001; 0.67±0.49 G/L vs 0.33±0.17 G/L, P<0.001; 474±123 G/L vs 376±89 G/L, P<0.001, respectively). At colonosco-py, lymphonodular hyperplasia or aphthous ulceration were present in 83% of patients. Twenty-two patients were given L-amino acid-based formula and 8 contin-ued the previous feeding. Time to cessation of rectal bleeding was shorter in the special formula feeding group (mean, 1.4 wk; range, 0.5-3 wk) when com-pared with the breast-feeding group (mean, 5.3 wk; range, 2-9 wk). Nevertheless, none of the patients ex-hibited rectal bleeding at the 3-mo visit irrespective of the type of feeding. Peripheral eosinophilia and cessa-tion of rectal bleeding after administration of elemental formula correlated with a higher density of mucosal eosinophils. CONCLUSION: Infant hematochezia, after cow's milk allergy exclusion, is generally a benign and probably self-limiting disorder despite marked mucosal abnor-mality. Formula feeding results in shorter time to cessa-tion of rectal bleeding; however, breast-feeding should not be discouraged in long-lasting hematochezia. | Kriszta Molnár Petra Pintér Hajnalka Gyrffy ron Cseh Katalin Eszter Müller András Arató Gábor Veres | 2013 | World Journal of Gastroenterology2013，19，24： | 3 |
| 4 | Survival of rapidly frozen hatched mouse blastocysts 显示文摘 | Pribenszky C Cseh S Abonyi TZ | 2003 | Zygote2003，11，4： | 1 |
| 5 | Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by rho family gtpases 显示文摘 | Fernandez-Sauze S Grall D Cseh B | 2009 | Exp Cell Res2009，315，12： | 1 |
| 6 | Deliveries from embryos fertilized with spermatozoa obtained from cryopreserved testicular tissue 显示文摘 | Konyo J Kanyo K Cseh S | 2006 | J Assist Reprod Genet2006，23，5： | 1 |
| 7 | Matrix metalloproteinase inhihitors: a critical appraisal of design principles and pro- posed therapeutic utility显示文摘 | Dorman G Cseh S Hajdu I | 2010 | Drugs2010，70，： | 1 |
| 8 | Effects ofmelatonin treatment onfollicular development and oocyte quality in Chios ewes - short communication显示文摘 | Tsiligianni T Valasi I Cseh S | 2009 | Acta Vet Hung2009，57，2： | 1 |
| 9 | Studies on factors affecting superovulation and embryo transfer in Hungarian merino ewes显示文摘 | Cseh S Sohi L | 2001 | Acta Vet Hung2001，49，4： | 1 |
| 10 | Matrix Metalloproteinase Inhibitors A Critical Appraisal of Design Principles and Proposed Therapeutic Utility显示文摘 | Dorman G Cseh S Hajdu I | 2010 | Drugs2010，70，8： | 1 |
| 11 | Substrate specificities of recombi-nant mannan-binding lectin-associated serine proteases-1and-2显示文摘 | Rossi V Cseh S Bally I | 2001 | J Biol Chem2001，276，40： | 1 |
| 12 | Improving post-thaw survival of cryopreserved mouse blastocysts by hydrostatic pressure challenge显示文摘 | Pribenszky C Molnar M Cseh S | 2005 | Anim Reprod Sci2005，87，12： | 1 |
| 13 | Matrix metalloproteinase inhibitors a critical appraisal of design principles and proposed therapeutic utility 显示文摘 | DORMAN G CSEH S HAJDU I | 2010 | Drugs2010，70，8： | 1 |
| 14 | Vitrification of mouse embryos in two cryoprotectant solutions 显示文摘 | CSEH S HORLACHER W | 1999 | Theriogenology1999，52，1： | 1 |
| 15 | Interaction properties ofhuman mannan-binding lectin(MBL)-associated serine protea-ses-1and-2,MBL-associated protein 19,and MBL显示文摘 | Thielens N M Cseh S Thiel S | 2001 | J Immu-nol2001，166，8： | 1 |
| 16 | Adsorption-desorption Characteristics of Polychlorinated Biphenyls on Various Polymers Commonly Found in Laboratories显示文摘 | Cseh T Sanschagrin S Hawari J | 1989 | Applied and Environmental Microbiology1989，55，12： | 1 |
| 17 | The effect of quick-freezing in ethylene glycol on morphologi- cal in vitro development of mouse embryos frozen at dif- ferent preimplantation stages 显示文摘 | Cseh S Corselli J Nehlsen-Cannarella SL | 1997 | Theriogenology1997，48，1： | 1 |
| 18 | Assisted reproductive technologies in the reproductive management of small ruminants 显示文摘 | Amiridis G S Cseh S | 2012 | Anim Reprod Sci2012，130，34： | 1 |
| 19 | Deliveries from embryos fertilized with Spermatozoa obtained from cryopreserved testicular tisue显示文摘 | Konyo J Konyo K Cseh S | | 0，，05： | 1 |
| 20 | The effect of quick-freezing in ethylene glycol on morphological in vitro development of mouse embtyos frozen at different preimplantation stages 显示文摘 | Cseh S Cotselli J Nehlsen-Cannarella SL | 1997 | Therogenolog1997，48，： | 1 |
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