|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Early experience in human hybrid transgastric and transvaginal endoscopic cholecystectomy显示文摘 | Gustavo Salinas Lil Saavedra Hellen Agurto Rosa Quispe Edwin Ramírez José Grande Juan Tamayo Victoria Sánchez Daniel Málaga Jeffrey M. Marks | 2010 | Surgical Endoscopy2010，，5： | 2 |
| 2 | Prophylaxis with ketotifen in rats with portal hypertension:involvement of mast cell and eicosanoids显示文摘BACKGROUND:Since we have previously shown an increase of mast cells in the small bowel and in the mesenteric lymph nodes in the rats with prehepatic portal hypertension,it can be hypothesized that this essential inflammatory cell would be involved in the pathogeny of the splanchnic changes related to portal hypertension. METHODS:To verify this hypothesis,we first studied mast cell infiltration in the ileum and in the mesenteric lymph nodes in sham-operated male Wistar rats(n=12) and in short-term prehepatic portal hypertensive rats (n=12),and the serum levels of rat mast cell protease Ⅱ(RMCP-Ⅱ)by ELISA.In a second set of experiments ketotifen,a mast cell stabilizer drug,was administered to sham-operated(n=10)and portal hypertensive(n=12) rats 24 hours before the intervention and prostanoids (PGE2,PGI2,TXB2)and leukotrienes(LTC4,LTB4)were assayed by RIA,mast cell infiltration in the ileum and in the mesenteric lymph nodes and the serum levels of RMCP-Ⅱwere also studied,to show its effectiveness to prevent the mesenteric alterations produced by the inflammatory mediators released by the mast cell. RESULTS:Forty-eight hours after the intervention RMCP-Ⅱ (P<0.05),PGE2(P<0.001)and LTC4 serum levels decreased and mast cell number and RMCP-Ⅱlevels increased in mesenteric lymph nodes in portal hypertensive rats.Prophylactic administration of ketotifen reduced portal pressure(P<0.001),serum levels of PGE2(P<0.001)and RMCP-Ⅱ(P<0.001)in mesenteric lymph nodes. CONCLUSIONS:In acute portal hypertension in the rat,the mast cell translocation from intestinal mucosa to mesenteric lymph nodes,where they are activated and degranulates,would represent a defence mechanism to avoid the activation of an acute and massive inflammatory response in this location.Prophylactic administration of ketotifen is able to reduce the splanchnic inflammatory changes related to acute portal hypertension in the rat. | Fernando Sánchez-Patán Raquel Anchuelo Elena Vara Cruz García Yolanoa Saavedra Patri Vergara Carmen Cuellar Marta Rodero Maria-Angeles Aller Jaime Arias | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，4： | 2 |
| 3 | A' bedside scoring system (' Candida score') for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization 显示文摘 | Le6n C Ruiz-Santana S Saavedra'P 'et ai | 2006 | Crit Care Med2006，34，3： | 1 |
| 4 | Cord blood transplantation from unrelated donors in adults with high-risk acute myeloid leukemia显示文摘 | Sanz J Sanz MA Saavedra S | 2010 | Biol Blood Marrow Transplant2010，16，： | 1 |
| 5 | Azathioprine during pregnancy in systemic lupus erythematosus patients is not associated with poor fetal outcome 显示文摘 | Saavedra MA Sánchez A Morales S | 2015 | Clin Rheumatol2015，34，7： | 1 |
| 6 | A bedside scoring system(Candidascore)for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization显示文摘 | Leon C Ruiz-Santana S Saavedra P | 2006 | Crit Care Med2006，34，3： | 1 |
| 7 | Identification of anthocyanins of pinta boca (Solanum stenotomum) tubers显示文摘 | CRISTINA ALCALDE-EON SAAVEDRA G PASCUAL-TERESA S D | 2004 | Food Chemistry2004，86，3： | 1 |
| 8 | Usefulness of the“Candidascore”for discriminating between Candidacolonization and invasive candidiasis in non-neutropenic critically ill patients:aprospective multicenter study显示文摘 | Leon C Ruiz-Santana S Saavedra P | 2009 | Crit Care Med2009，37，5： | 1 |
| 9 | Conformational changes in actomyosin from post-spawned hake stored on ice显示文摘 | ROURA S J SAAVEDRA J P TRUCO R E | 1992 | J of Food Sci1992，57，： | 1 |
| 10 | Evanescent sensing in doped sol-gel glass films显示文摘 | Lee J E Saavedra S S | 1994 | Anal Chem Acta1994，285，： | 1 |
| 11 | A cold test for myasthenia gravis显示文摘 | Saavedra J Femminini R Koehen S | 1979 | Neurology1979，29，： | 1 |
| 12 | Neuroendocrine carcinomas of the stomach: a clinicopathologic evaluation 显示文摘 | Staren ED Lott S Saavedra VM | 1992 | Surgery1992，112，6： | 1 |
| 13 | The bioenergetics of cancer: Is glycolysis the main ATP sup- plier in all tumor cells显示文摘 | Moreno - Sdnchez R Rodriguez - Enriquez S Saavedra E | 2009 | Biofactors2009，35，： | 1 |
| 14 | The contagious leader: im- pact of the leader's mood on the mood of group mem- bers, group affective tone, and group processes显示文摘 | Sy T Cote S Saavedra R | 2005 | The Journal of applied psychology2005，90，2： | 1 |
| 15 | Effect of blue green light on growth rate and chemical composition of three diatoms显示文摘 | Voltolina D | 1996 | J Appl Phycol1996，8，： | 1 |
| 16 | A bedside scoring system('Candida score')for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization显示文摘 | León C Ruiz-Santana S Saavedra P | 2006 | Scand J Infect Dis2006，34，3： | 1 |
| 17 | Identification of anthocyanins of pinta boca (Solanum stenotomum) tubers显示文摘 | ALCALDE-EON C SAAVEDRA G de PASCUAL-TERESA S | 2004 | Food Chem2004，86，： | 1 |
| 18 | Fresh-cut radish using different cut types and storage temperatures显示文摘 | Juan Saavedra A Fablana F S Lilia S H | 2006 | Postharvest Biology and Technology2006，，2： | 1 |
| 19 | Quasinormal modes of the extremal BTZ black hole显示文摘 | CRISOSTOMO J LEPE S SAAVEDRA J | 2004 | Class Quant Grav2004，21，： | 1 |
| 20 | Integrated Optical Attenuated Total Reflection Spectrometry of Aqueous Superstreets using Prism-coupled Polymer Waveguides 显示文摘 | Saavedra S S Hitherto W M | 1990 | Anal Chem1990，82，20： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员