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| 1 | Autologous CD34^+ and CD133^+ stem cells transplantation in patients with end stage liver disease显示文摘AIM:To assess the utility of an autologous CD34 + and CD133 + stem cells infusion as a possible therapeutic modality in patients with end-stage liver diseases.METHODS:One hundred and forty patients with endstage liver diseases were randomized into two groups.Group 1,comprising 90 patients,received granulocyte colony stimulating factor for five days followed by autologous CD34 + and CD133 + stem cell infusion in the portal vein.Group 2,comprising 50 patients,received regular liver treatment only and served as a control group.RESULTS:Near normalization of liver enzymes and improvement in synthetic function were observed in 54.5% of the group 1 patients;13.6% of the patients showed stable states in the infused group.None of the patients in the control group showed improvement.No adverse effects were noted.CONCLUSION:Our data showed that a CD34 + and CD133 + stem cells infusion can be used as supportive treatment for end-stage liver disease with satisfactory tolerability. | Hosny Salama Abdel-Rahman N Zekri Abeer A Bahnassy Eman Medhat Hanan A Halim Ola S Ahmed Ghada Mohamed Sheren A Al Alim Ghada M Sherif | 2010 | World Journal of Gastroenterology2010，16，42： | 16 |
| 2 | Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions显示文摘AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma(HCC),in relation to other hepatic diseases.METHODS Eighty-eight patients were included in the current study and represented patients with HCC(20),liver cirrhosis(28) and chronic hepatitis(CH;25),and normal controls(NC;15).Peripheral blood was isolated for immunophenotyping of active myeloid dendritic cells(m DCs;CD1 c and CD40),mature inactive myeloid cells(CD1 c and HLA),active plasmacytoid cells(p DCs;CD303 and CD40),mature inactive p DCs(CD30 and HLA),active natural killer(NK) cells(CD56 and CD161),active NK cells(CD56 and CD314) and inactive NK cells(CD56 and CD158) was done by flow cytometry.Serum levels of interleukin(IL)-2,IL-10,IL-12,IL-1β,interferon(IFN)-α,IFN-γ and tumor necrosis factor(TNF)-αR2 were assessed by ELISA.RESULTS Active m DCs(CD1 C+/CD40+) and inactive m DCs(CD1 c+/HLA+) were significantly decreased in HCC patients in relation to NC(P < 0.001).CD40+ expression on active p DCs was decreased in HCC patients(P < 0.001),and its level was not significantly changed among other groups.Inactive p DCs(CD303+/HLA+),inactive NKs(CD56+/CD158+) and active NKs(CD56+/CD161+) were not statistically changed among the four groups studied;however,the latter was increased in CH(P < 0.05).NKG2 D was statistically decreased in HCC,CH and cirrhosis(P < 0.001),and it was not expressed in 63%(12/20) of HCC patients.There was significant decrease of IL-2,IFN-α and IFN-γ(P < 0.001),and a significant increase in IL-10,IL-1β,and TNF-αR2(P <0.01,P < 0.001 and P < 0.001;respectively) in HCC patients.There was inverted correlation between IL-12 and IL-1β in HCC(r =-0.565,P < 0.01),with a strong correlation between p DCs(CD303+/CD40+) and NKs(CD56+/CD161+;r = 0.512,P < 0.05) as well as inactive m DCs(CD1 c+/HLA+) and inactive NK cells(CD56+/CD158+;r = 0.945,P < 0.001).CONCLUSION NKG2 D,CD40,IL-2 and IL-10 are important modulators in the development and progression of HCC. | Abdel-Rahman N Zekri Somaya El Deeb Abeer A Bahnassy Abeer M Badr Mona S Abdellateif Gamal Esmat Hosny Salama Marwa Mohanad Ahmed Esam El-dien Shimaa Rabah Assmaa Abd Elkader | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 3 | N-termi- nal pro-BNP in acute coronary syndrome patients with ST eleva- tion (STE-ACS) versus non ST elevation (NSTE-ACS)显示文摘 | SALAMA R EL-MONIEM A EL-HEFNEY N | 2011 | Int J Health Sci2011，5，1： | 1 |
| 4 | Malignant peripheral primitive neuroectodermal tumor-peripheral neuroepithelioma of the head and neck:a clinicopathologic study of five cases and review of the literature显示文摘 | Nikitakis N G Salama A R O'Malley B W | 2003 | Head Neck2003，25，6： | 1 |
| 5 | Lassification of capacitor allocation techniques 显示文摘 | NG H N SALAMA M M A CHIKHANI A Y | 2000 | IEEE Trans Power Delivery2000，15，1： | 1 |
| 6 | Trends in partial discharge pattern classification: a survey显示文摘 | SAHOO N C SALAMA M M A BARTNIKAS R | 2005 | IEEE Transactions on Dielectrics and Electrical Insulation2005，12，2： | 1 |
| 7 | CMOS Operational Transresistance Amplifier for Analog Signal Processing显示文摘 | Salama K N Soliman A M | 1999 | Microelectronics1999，30，2： | 1 |
| 8 | Mesenchymal stem cell content of human vertebral bone marrow 显示文摘 | Ahrens N Tormin A Paulus M Roosterman D Salama A Krenn V | 2004 | Transplantation2004，78，6： | 1 |
| 9 | Trends in partial discharge pattern classification:A survey显示文摘 | SAHOO N C SALAMA M M A BARTNIKAS R | 2005 | IEEE Transactions on Dielectrics and Electrical Insulation2005，12，2： | 1 |
| 10 | CMOS operational trans resistance amplifier for analog signal processing显示文摘 | Salama K N Soliman A M | 1999 | Microelectronics J1999，30，2： | 1 |
| 11 | Novel oscillators using the operational transresistance amplifier 显示文摘 | Salama K N Soliman A M | 2000 | Microelectronics J2000，89，1： | 1 |
| 12 | Microvascular testicular blood flow as evaluated by laser Doppler flowmetry after the surgical induction of varicocele 显示文摘 | Salama N Bergh A Damber JE | 2001 | Arch Andro12001，46，3： | 1 |
| 13 | Validation of the Spectrophotometric Determination of Omeprazole and Pantoprazole Sodium via Their Metal Chelates显示文摘 | SALAMA F EL-ABASAWY N ABDEL RAZEQ S A | 2003 | Journal of Pharmaceutical and Biomedical Analysis(S0371-7085)2003，33，3： | 1 |
| 14 | An RNA gene expressed during cortical development evolved rapidly in humans显示文摘 | Pollard K S Salama S R Lambert N Lambot M A Coppens S Ped ersen J S | 2006 | Nature2006，443，： | 1 |
| 15 | Classification of capacitor allocation techniques显示文摘 | Ng H N Salama M M A Chikhani A Y | 2000 | IEEE Trans on Power Delivery2000，15，1： | 1 |
| 16 | Trends in partial discharge pattern classification: a survey显示文摘 | Sahoo N C Salama M M A Bartnikas R | 2005 | IEEE Trans on Dielectrics and Electrical Insulation2005，12，2： | 1 |
| 17 | Utilization of plant proteins in the manufacture of cheese analogs显示文摘 | Ahmed N S Hassan F A M Salama F M M | 1995 | Egyptian Journal of Food Science1995，23，： | 1 |
| 18 | Validation of HPLC method for determination of tetracyclineresidues in chickenmeat and liver 显示文摘 | SHALABY A R SALAMA N A ABOU-RAYA S H | 2011 | Food Chemistry2011，124，4： | 1 |
| 19 | Tight junction modulation and its relationship to drug dclivcry 显示文摘 | Salama N N Eddington N D Fasxno A | 2006 | Adv Drug Deliv Rev2006，58，1： | 1 |
| 20 | Trends in partial discharge pattern classification: a survey显示文摘 | Sahoo N C Salama M M A Bartnikas R | 2005 | IEEE Transactions on Dielectrics and Electrical Insulation2005，12，2： | 1 |
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