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| 1 | Synthesis and crystal structure study of 2′-Se-adenosine-derivatized DNA显示文摘The selenium derivatization of nucleic acids is a novel and promising strategy for 3D structure determination of nucleic acids.Selenium can serve as an excellent anomalous scattering center to solve the phase problem,which is one of the two major bottlenecks in macromolecule X-ray crystallography.The other major bottleneck is crystallization.It has been demonstrated that the incorporated selenium functionality at the 2′-positions of the nucleosides and nucleotides is stable and does not cause significant structure perturbation.Furthermore,it was observed that the 2′-Se-derivatization could facilitate crystallization of oligonucleotides with fast crystal growth and high diffraction quality.Herein,we describe a convenient synthesis of the 2′-Se-adenosine phosphoramidite,and report the first synthesis and X-ray crystal structure determination of the DNA containing the 2′-Se-A derivatization.The 3D structure of 2′-Se-A-DNA decamer 5′-GTACGCGT(2′-Se-A)C-3′2 was determined at 1.75 ? resolution,the 2′-Se-functionality points to the minor groove,and the Se-modified and native structures are virtually identical.Moreover,we have observed that the 2′-Se-A modification can greatly facilitate the crystal growth with high diffraction quality.In conjunction with the crystallization facilitation by the 2′-Se-U and 2′-Se-T,this novel observation on the 2′-Se-A functionality suggests that the 2′-Se moiety is sole responsible for the crystallization facilitation and the identity of nucleobases does not influence the crystal growth significantly. | SALON Jozef | 2010 | Science China Chemistry2010，53，1： | 3 |
| 2 | Comparison of the BEM and FEM Approach for the Electromagnetic Field Analysis in a Zoned Medium显示文摘 | Krajewski W Salon S J | 1993 | Communications in Numerical Methods in Engineering1993，9，10： | 1 |
| 3 | Converters, Compatibility and the Control of Interfaces 显示文摘 | Farrell J Saloner G | 1992 | The Journal of Industrial Economics1992，40，： | 1 |
| 4 | Major carotid plaque surface irregularities correlate with neurological symptoms显示文摘 | Troyer A Saloner D Pan XM | 2002 | Vasc Surg2002，35，2： | 1 |
| 5 | Mobility, poverty, and gender: Travel‘choices’of slum residents in Nairobi, Kenya显示文摘 | Salon D Gulyani S | 2010 | Transport Reviews2010，，30： | 1 |
| 6 | Chioosing How to Compete: Strategies and Tactics in Standardization 显示文摘 | Farrell Joseph Garth Saloner | 1994 | Journal of Economic Perspectives1994，1994，： | 1 |
| 7 | Artifacts in maximum-intensity-projection display of MR angiograms 显示文摘 | Anderson CM Saloner D Tsuruda JS | 1990 | AJR1990，154，： | 1 |
| 8 | An investigation of quality in CO2 laser cutting of aluminum显示文摘 | A Stournaras P Stavropoulos K Salonitis | 2009 | CIRP Journal of Manufacturing Science and Technology2009，2，1： | 1 |
| 9 | Artifacts in Maximum-intensity-projection Display of MR Angiography显示文摘 | Anderson CM Saloner D Tsuruda JS | 1990 | AJR1990，154，3： | 1 |
| 10 | Modem meningioma imaging techniques 显示文摘 | Saloner D Uzelac A Hetts S | 2010 | J Neurooncol2010，99，3： | 1 |
| 11 | Mobility, poverty, and gender: travel 'choices' of slum residents in Nairobi, Kenya 显示文摘 | Salon D Gulyani S | 2010 | Transport Reviews2010，30，5： | 1 |
| 12 | Transmis- sion Network Planning Using Linear Programming 显示文摘 | VILLASANA R GARVER L L Salon S J | 1985 | IEEE Transactions on Power Apparatus and Systems1985，104，2： | 1 |
| 13 | Standardization, Compatibility and Innovation显示文摘 | FARRELL J SALONER G | 1985 | RAND Journal of Economics1985，16，： | 1 |
| 14 | Standardization, compatibility, and innovation 显示文摘 | Farrell J Saloner S | 1985 | Rand Journal of Economics1985，16，： | 1 |
| 15 | Hybrid finite element boundary element solutions for three dimensional scalar potential problems 显示文摘 | MEUNIER G COULOMB J L SALON S J | 1986 | IEEE Transactions on Magnetics1986，22，5： | 1 |
| 16 | An analytical,numerical,and experimental approach to grind hardening显示文摘 | Chryssolouris G Tsirbas K Salonitis K | 2005 | Journal of Manufacturing Processes2005，7，1： | 1 |
| 17 | The Vertical Organization of Industry:Systems Competition versus Component Competition显示文摘 | Farrell Joseph Monroe Hunter and Saloner Garth | 1998 | Journal of Economics and Management Strategy1998，7，2： | 1 |
| 18 | Standardization,Compatibility,and Innovation显示文摘 | Joseph Farrell and Garth Saloner | 1985 | Rand Journal of Economics1985，16，1： | 1 |
| 19 | Economic issues in computer interface stand- ardization:the case of UNIX显示文摘 | SALONER G | 1990 | Economics of Innovation and New Technology1990，1，12： | 1 |
| 20 | Bodily self and schizophrenia: The loss of implicit self-body knowledge显示文摘 | Francesca Ferri Francesca Frassinetti Francesca Mastrangelo Anatolia Salone Filippo Maria Ferro Vittorio Gallese | 2012 | Consciousness and Cognition2012，，3： | 1 |
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