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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion显示文摘 | Philip N Newsome Ingolfur Johannessen Shelagh Boyle Evangelos Dalakas Karen A Mcaulay Kay Samuel Frances Rae Lesley Forrester Marc L Turner Peter C Hayes David J Harrison Wendy A Bickmore John N Plevris | 2003 | Gastroenterology2003，，7： | 2 |
| 3 | Cloning and sequencing of a Shiga - like toxin type II variant from Esche- richia coli strain responsible for edema disease of swine 显示文摘 | WEINSTEIN D L JACKSON M P SAMUEL J E | 1988 | Bacteri- ol1988，170，9： | 1 |
| 4 | Neurological outcome after surgical management of adult tethered cord syndrome 显示文摘 | Garces-Ambrossi G L McGirt M J Samuels R | 2009 | JNeurosurgSpine2009，11，3： | 1 |
| 5 | Cloning and sequencing of a Shiga-like toxin type Ⅱ variant from Escherichia coli strain responsible for edema disease of swine显示文摘 | WEINSTEIN D L JACKSON M P SAMUEL J E | 1988 | J Bacteriol1988，170，9： | 1 |
| 6 | Dissolution of iron intermetallics in Al-Si alloys through nonequilibrium beat treatment显示文摘 | ANANTHA N L SAMUEL F H Gruzleski J E | 1995 | Metallurgical and Materials Transactions1995，26，8： | 1 |
| 7 | The relationship between age and accuracy of foreign language pronuciation显示文摘 | Olson L L Samuels S J | 1973 | The Journal of Edu- cational Research1973，66，6： | 1 |
| 8 | The Trichoderma koningii aggregate species 显示文摘 | SAMUELS G J DODD S L LU B S | 2006 | Studies in Mycology2006，56，： | 1 |
| 9 | Hypcrea/Trichoderma (Ascomycota,Hypocreales,Hypocreaceae):species with green ascospores显示文摘 | Samuels J G | 2003 | Study in Mycology2003，48，： | 1 |
| 10 | A photoactivatable push-pull fluorophore for single-molecule imaging in live cells显示文摘 | Lord S J Conley N R Lee H L D Samuel R Liu N Twieg R J Moerner W E | | 0，，29： | 1 |
| 11 | Relationships of the Escherichia coli O157,O111,and 055 O-Antigen gene clusters with those of Salmonella enterica and Cittobacter freundii,which express identical O antigens显示文摘 | Samuel G Hogbin J Wang L | 2004 | J Bacteriol2004，186，： | 1 |
| 12 | An Architecture for Semi-Automated Radar Image Exploitation显示文摘 | Keith Sisterson L John R Delaney Samuel J Gravina | 1998 | Lincoln Lab1998，11，2： | 1 |
| 13 | Crystallization behavior of iron-containing inter metallic compounds in 319 aluminum alloy显示文摘 | ANANTHANARAYANAN L SAMUEL F H Gruzleski J E | 1994 | Metallurgical and Materials Transactions A1994，25，5： | 1 |
| 14 | Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial显示文摘 | Jayant S Vaidya David J Joseph Jeffrey S Tobias Max Bulsara Frederik Wenz Christobel Saunders Michael Alvarado Henrik L Flyger Samuele Massarut Wolfgang Eiermann Mohammed Keshtgar John Dewar Uta Kraus-Tiefenbacher Marc Sütterlin Laura Esserman Helle MR Ho | 2010 | The Lancet2010，，9735： | 1 |
| 15 | Effects of preemptive epidural analgesia on post-thoracotomy pain显示文摘 | BONG C L SAMUEL M Ng J M | 2005 | J Cardiothorac Vasc Anesth2005，19，6： | 1 |
| 16 | Experimental study on pore nuleation by indusinons in aluminum eastings 显示文摘 | ANANTHANARAYANAN L SAMUEL F H GRUZLESKI J E | 1992 | AFS Transactions1992，24，8： | 1 |
| 17 | Process capability indices-a review,1992-2000显示文摘 | Samuel K Norman L J | 2002 | Journal of Quality Technology2002，1，： | 1 |
| 18 | Crystallization behavior of iron-containing intermetallic compounds in 319 aluminum alloy 显示文摘 | Ananthanarayanan L Samuel F H Gruzleski J E | 1994 | Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science1994，25，8： | 1 |
| 19 | Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease显示文摘 | Locke N R Royce S G Wainewright J S Samuel C S Tang M L | 2007 | Am J Respir Cell Mol Biol2007，36，： | 1 |
| 20 | Synthesis of enzymatically active human α-- L-- iduronidase in Arabidopsis cgI ( complex glyean -- deficient) seeds 显示文摘 | Downing W L Galpin J D Clemens S Lauzon S M Samuels A L Pidkowich M S Clarke L A and Kermode A R | 2006 | Plant Biotechnology Journal2006，4，： | 1 |
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