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| 1 | Adverse events with bismuth salts for Helicobacter pylori eradication:Systematic review and meta-analysis显示文摘AIM: To assess the safety of bismuth used in Helico- bacter pylori (H pylori) eradication therapy regimens. METHODS: We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled tri- als comparing bismuth with placebo or no treatment, or bismuth salts in combination with antibiotics as part of eradication therapy with the same dose and duration of antibiotics alone or, in combination, with acid suppres- sion. Total numbers of adverse events were recorded. Data were pooled and expressed as relative risks with 95% confidence intervals (CI). RESULTS: We identified 35 randomised controlled tri- als containing 4763 patients. There were no serious adverse events occurring with bismuth therapy. There was no statistically significant difference detected in total adverse events with bismuth [relative risk (RR) = 1.01; 95% CI: 0.87-1.16], specific individual adverse events, with the exception of dark stools (RR = 5.06; 95% CI: 1.59-16.12), or adverse events leading to withdrawal of therapy (RR = 0.86; 95% CI: 0.54-1.37). CONCLUSION: Bismuth for the treatment of H pylori is safe and well-tolerated. The only adverse event oc- curring significantly more commonly was dark stools. | Alexander C Ford Peter Malfertheiner Monique Giguère José Santana Mostafizur Khan Paul Moayyedi | 2008 | World Journal of Gastroenterology2008，14，48： | 62 |
| 2 | Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis显示文摘Ulcerative colitis(UC)is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum.The hallmark clinical symptom of UC is bloody diarrhea.The clinical course is marked by exacerbations and remissions,which may occur spontaneously or in response to treatment changes or intercurrent illnesses.UC is most commonly diagnosed in late adolescence or early adulthood,but it can occur at any age.The incidence of UC has increased worldwide over recent decades,especially in developing nations.In contrast,during this period,therapeutic advances have improved the life expectancy of patients,and there has been a decrease in the mortality rate over time.It is important to emphasize that there is considerable variability in the phenotypic presentation of UC.Within this context,certain clinical and demographic characteristics are useful in identifying patients who tend to have more severe evolution of the disease and a poor prognosis.In this group of patients,better clinical surveillance and more intensive therapy may change the natural course of the disease.The aim of this article was to review the epidemiology and demographic characteristics of UC and the factors that may be associated with its clinical prognosis. | Bruno César da Silva Andre Castro Lyra Raquel Rocha Genoile Oliveira Santana | 2014 | World Journal of Gastroenterology2014，20，28： | 48 |
| 3 | Association of Helicobacter pylori infection and giardiasis: Results from a study of surrogate markers for fecal exposure among children显示文摘AIM: To investigate whether Helicobacter pylori (H pykori)infection is associated with hepatitis A virus (HAV) infection, presence of enteroparasites, and other surrogates of fecal exposure.METHODS: We conducted a cross-sectional study in 121 children consecutively admitted at a pediatric hospital inSalvador, Brazil.H pylori and HAV infection were identified by the presence of serum antibodies. Stool specimens were examined for the presence of ova and parasites. A structured questionnaire inquiring about sanitary conditions and life style was applied to each subject. RESULTS: Fifty-one of the 121 children (42.1%) werefound to be seropositive for H pylori, and 45 (37.2%) for HAV. The seroprevalence ofHpyloriand HAV both increased significantly with age. Cross-tabulation of data showed that 26 (21.5%) were seropositive and 51 (42.1%) were negative for bothHpyloriand HAV antibodies (χ2 = 7.18,OR = 2.8, CI 1.30-5.97). The age adjusted OR for an HAV-infected child being H pylori positive was 2.3 (CI1.02-5.03). The agreement between H pylori and HAVseropositivity was fair (κ = 0.24). After controlling for possible confounding, the variables remaining independently associated with seropositivity to H pyloriwere age,presence of Giardia lamblia in feces (OR = 3.2, 95%CI, 1.1-9.5) and poor garbage disposal quality (OR = 2.4,95%CI, 1.1-5.1).CONCLUSION: Our data suggest that H pylori infection is associated with surrogate markers of fecal exposure. Thus, we conclude that the fecal-oral route is relevant in the transmission of HP among children in an urban setting of a developing country. The association observed between G. lamblia and H pylori infection may have several explanations. Further studies to investigate this relationship are warranted. | Edson Duarte Moreira Jr Victor Bastos Nassri Rafaela Sousa Santos Junísia Ferraz Matos Wilson Andrade de Carvalho Célia Stolve Silvani Círia Santana e Sant'Ana | 2005 | World Journal of Gastroenterology2005，11，18： | 3 |
| 4 | Subclinical hypothyroidism in young women with polycystic ovary syndrome: an analysis of clinical, hormonal, and metabolic parameters显示文摘 | Cristina Laguna Benetti-Pinto Vanessa Ribeiro Santana Berini Piccolo Heraldo Mendes Garmes Cássia Raquel Teatin Juliato | 2012 | Fertility and Sterility2012，，： | 2 |
| 5 | First record of Meloidogyne enterolobii on guava in the state of Alagoas,Brazil显示文摘 | Castro J M C Santana T A S | 2010 | Nematologia Brasileira2010，34，3： | 1 |
| 6 | Use of Autologous Mesenchymal Stem Cells Derived from Bone Marrow for the Treatment of Naturally Injured Spinal Cord in Dogs显示文摘 | Euler Moraes Penha Cássio Santana Meira Elisalva Teixeira Guimar?es Marcus Vinícius Pinheiro Mendon?a Faye Alice Gravely Cláudia Maria Bahia Pinheiro Taiana Maria Bahia Pinheiro Stella Maria Barrouin-Melo Ricardo Ribeiro-dos-Santos Milena Botelho Pereira | 2014 | Stem Cells International2014，，： | 1 |
| 7 | The pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in cardiovascular disease: a comprehensive review 显示文摘 | MIHOS C G SALAS M J SANTANA O | 2010 | Cardiol Rev2010，18，6： | 1 |
| 8 | Electrodeposition and corrosion behaviour of a Ni-W-B amorphous alloy显示文摘 | SANTANA R A C PRASAD S | 2006 | Journal of Applied Electrochemistry2006，36，1： | 1 |
| 9 | The use of spray drying technology to reduce bitter taste of casein hydrolysate 显示文摘 | Favaro C S Santana A S Monterrey E S | 2010 | Food Hydrocolloids2010，24，4： | 1 |
| 10 | Development of a tunable LED-based colorimetric source显示文摘 | BROWN W SANTANA C EPPELDAUER P | 2002 | Journal of Research of the National Institute of Standards and Technology2002，107，4： | 1 |
| 11 | G-Dominance: reference point based dominance for multi-objective metaheuristics 显示文摘 | MOLINA J SANTANA L V COELLO C A C | 2009 | European Journal ofOperational Research2009，197，2： | 1 |
| 12 | Determination of para-synephrine and meta-synephrine positional isomers in bitter orange-containing dietary supplements by LC/UV and LC/MS/MS显示文摘 | Jose Santana Katherine E Sharpless Bryant C Nelson | 2008 | Food Chemistry2008，109，： | 1 |
| 13 | A comparison of face and facial feature detectors based on the Viola-Jones general object detection framework显示文摘 | Santana M C D6niz-Su/trez O Hemindez-Sosa D | 2011 | Mach Vis Appl2011，22，3： | 1 |
| 14 | A novel route to exreme vacua: the non-evaporable getter thin film coatings 显示文摘 | Benvenuti C Cazeneuve J M Chiggiato P Cicoira F Escudeiro Santana A Johanek V Ruzinov V Fraxedas J | 1999 | Vacuum1999，53，： | 1 |
| 15 | Oncogenic H-ras induces cyclin B1 expression in a p53-independent manner显示文摘 | SANTANA C ORTEGA E GARCIA-CARRANCA A | 2002 | Mutat Res2002，508，12： | 1 |
| 16 | Kinetics and Tthermodynamics of Textile Dye Adsorption from Aqueous Solutions Using Babassu Coconut Mesocarp显示文摘 | Vieira A P Santana S A A Bezerra C W B | 2009 | J Hazard Mater2009，166，： | 1 |
| 17 | Association of the estrogen receptor gene Pvu Ⅱ restriction polymorphism with expected progeny differences for reproductive and performance traits in swine herds in Brazil显示文摘 | Santana B A A Biase F H Antunes R C | 2006 | Genet Mol Biol2006，29，2： | 1 |
| 18 | Vacuum properties of TiZrV non-evaporable getter films 显示文摘 | Benvenuti C Chiggiato P Costa Pinto P Escudeiro Santana A Hedley T Mongelluzzo A Ruzinov V Wevers I | 2001 | Vacuum2001，60，： | 1 |
| 19 | A study of ion-exchange chromatography in an expanded bed for bovine albumin recovery显示文摘 | Severo Jr J B Souza R Rd Santana J C C | 2009 | Brazilian Archives of Biology and Technology2009，52，2： | 1 |
| 20 | Use of non - ionic surfactant solutions for the extraction and preconcentration of phenolic compounds in water prior to their HPLC -UV detection 显示文摘 | MAHISGO SANTANA C SOSA FERRERA Z SANTANA RODRIGUEZ J J | 2002 | Analyst2002，，127： | 1 |
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