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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | A readout magnet for prepolarized MRI显示文摘 | Morgan P Conolly S Scott G | 1996 | Magn Reson Med1996，36，4： | 1 |
| 3 | T lymphocyte subpopulations in idiopathic thrombocytopenic purpura (ITP) 显示文摘 | Scott C S Wheeler R Ford P | 1983 | Scand J Haematol1983，40，： | 1 |
| 4 | Gold and trace element zonation in pyrite using a laser imaging technique: Implications for the timing of gold in orogenic and Carlin- style sediment- hosted deposits 显示文摘 | R R Large L Danyushevsky C Hollit V Maslennikov S Meffer S Gilbert S Bull R Scott P Emsbo H Thomas B Singh J Foster | 2009 | Economic Geology2009，104，5： | 1 |
| 5 | Growth mecha- nisms for single - wall carbon nanotubes a laser ablation process 显示文摘 | Scott C D Arepalli S Nikolaev P | 2002 | Appl Phys a - Mater2002，74，1： | 1 |
| 6 | Cesarean delivery for fetal distress: Rate and risk factors 显示文摘 | CHAUHAN S P MAGANN E F SCOTT J R | 2003 | Obstet Gynecol Surv2003，58，5： | 1 |
| 7 | Total knee arthroplasty with the PFC system results at a minimum of ten years and survivorship analysis 显示文摘 | Schai P A Thornhill T S Scott R D | 1998 | J Bone Joint Surg Br1998，80，5： | 1 |
| 8 | An exploration of the meaning and consequences of workaholism显示文摘 | Scott K S Moore K S Miceli M P | 1997 | Human Rela- tions1997，50，： | 1 |
| 9 | Risk of cerebrovascular events after neck and supraclavicular radiotherapy:a systematic review显示文摘 | Scott A S Parr L A Johnstone P A | | 0，，02： | 1 |
| 10 | Comparison of column phases for separation of derivatized trichothecenes by capillary gas chromatography显示文摘 | Scott P M Kanhere S R | 1986 | Journal of Chromatography1986，368，2： | 1 |
| 11 | Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression显示文摘 | Scott S A Lakshimikuttysmmna A Sheridan D P | 2007 | Experimental hematology2007，35，2： | 1 |
| 12 | Imaging taste responses in the fly brain reveals a functional map of taste category and behavior 显示文摘 | Marella S Fischler W Kong P Asgarian S Rueckert E Scott K | 2006 | Neuron2006，49，： | 1 |
| 13 | A procedure for miniseale preparation of Pyricularia grisea DNA显示文摘 | SCOTT R P ZEIGLER R S NELSON R J | 1993 | International Rice Research Notes1993，18，1： | 1 |
| 14 | Parent-age analysis using RAPD-PCR显示文摘 | Haymes K M Williams S M | 1992 | Nucleic Acid Res1992，20，： | 1 |
| 15 | Application of ionic liquids as low-volatility plasticizers for PMMA 显示文摘 | Scott Mark P Rahman Mustafizur Brazel Chriastopher S | 2003 | European Polymer Journal2003，39，10： | 1 |
| 16 | Prion protein biology显示文摘 | PRUSINER S P SCOTT M R DEARMOND S J | 1998 | Ce111998，93，： | 1 |
| 17 | Molded glass aspheric optics hit the target for precision and cost显示文摘 | EDWARD P DAVID S SCOTT C | 2007 | Laser Focus World2007，12，： | 1 |
| 18 | Gaschromatography with electron cap ture and masssp ectrom etricdetection of deoxyn-ivalenol in wheat and othergrains显示文摘 | SCOTT P M LAU P Y KANHERE S R | 1981 | JAssoc Off AnalChem1981，64，： | 1 |
| 19 | Neonatal measles immunity in rural Kenya: the influence of HIV and placental malaria infections on placental transfer of antibodies and levels of antibody in maternal and cord serum samples 显示文摘 | Scott S Cumberland P Shulman CE | 2005 | J Infect Dis2005，191，11： | 1 |
| 20 | Comparison study of the biorthogonal spline wavelet filting for areal rough surfaces显示文摘 | Xiao S J Jians X Q Blunt L Scott P J | 2001 | Maching Tools&Manufacture2001，41，： | 1 |
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