|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Does an association exist between chronic pancreatitis and liver cirrhosis in alcoholic subjects?显示文摘AIM: To study the possible association between chronic pancreatitis (CP) and liver cirrhosis (LC) of alcoholic etiology,after excluding any other causes.METHODS: One hundred and forty consecutive alcoholic patients were subdivided into three groups: CP (n = 53),LC (n = 57),and asymptomatic alcoholic (n = 30).Clinical,biochemical and morphological characteristics,Child-Pugh index,indocyanine green test,and fecal pancreatic elastase-1 test were assessed.RESULTS: In patients with cirrhosis,major clinical manifestations of CP such as pancreatic pain and steatorrhea,as well as imaging alterations of CP such as calcifications,duct dilation and pseudocysts were absent; insulin-dependent diabetes was present in 5.3% of cases,and elastase-1 test was altered in only 7%,and severely altered in none.In patients with CP,clinical characteristics of cirrhosis such as ascites,encephalopathy and gastrointestinal hemorrhage were present in one case,Child-Pugh grade > A in 5.7%,and altered indocyanine green test in 1.9% cases.In asymptomatic alcoholism,there was only a non-coincident alteration of elastase-1 test and indocyanine test in 14.8% and 10%,respectively,but other characteristics of cirrhosis or CP were absent.An inverse correlation (r = -0.746) between elastase-1 test and indocyanine test was found in alcoholic patients.CONCLUSION: There is a scarce coincidence in clinical and morphological alterations among patients with CP or LC of alcoholic etiology,but an inverse correlation between pancreatic and liver function tests.These findings support that these alcoholic diseases evolve in a different manner and have different etiopathogenesis. | Luis Aparisi Luis Sabater Juan Del-Olmo Juan Sastre Miguel-Angel Serra Ricardo Campello Daniel Bautista Abdalla Wassel José-Manuel Rodrigo | 2008 | World Journal of Gastroenterology2008，14，40： | 4 |
| 2 | Viroids and Hepatitis Delta Virus显示文摘 | Ricardo Flores Susana Ruiz-Ruiz Pedro Serra | 2012 | Semin Liver Dis2012，，03： | 2 |
| 3 | Viroids and Hepatitis Delta Virus显示文摘 | Ricardo Flores Susana Ruiz-Ruiz Pedro Serra | 2012 | Semin Liver Dis2012，，03： | 2 |
| 4 | Identification of the atomic scale structure of the La 0.65 Nd 0.15 Mg 0.20 Ni 3.5 alloy synthesized by spark plasma sintering显示文摘 | Virginie Serin Junxian Zhang César Magén Rapha?l Serra Martin J. H?tch Lucille Lemort Michel Latroche Manuel Ricardo Ibarra Bernard Knosp Patrick Bernard | 2013 | Intermetallics2013，，： | 1 |
| 5 | SARS-CoV-2 productively infects primary human immune system cells in vitro and in CoviD-19 patients显示文摘The severe acute respiratory syndrome coronavirus 2(SARS-CovV-2)infection is associated with a hyperinflammatory state and lymphocytopenia,a hallmark that appears as both signature and prognosis of disease severity outcome.Although cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion,it is still unclear whether direct SARS-Cov-2 infection of immune cells could also play a role in this scenario by harboring viral replication.We found that monocytes,as well as both B and T lymphocytes,were susceptible to SARS-Cov-2 infection in vitro,accumulating double-stranded RNA consistent with viral RNA replication and ultimately leading to expressive T cell apoptosis.In addition,flow cytometry and immunofluorescence analysis revealed that SARS-Cov-2 was frequently detected in monocytes and B lymphocytes from coronavirus disease 2019(CoVID-19)patients.The rates of SARS-Cov-2-infected monocytes in peripheral blood mononuclear cells from CoVID-19 patients increased over time from symptom onset,with SARS-CoV-2-positive monocytes,B cells,and CD4+T lymphocytes also detected in postmortem lung tissue.These results indicated that SARS-CoV-2 infection of blood-circulating leukocytes in covID-19 patients might have important implications for disease pathogenesis and progression,immune dysfunction,and virus spread within the host. | Marjorie C.Pontelli italo A.Castro Ronaldo B.Martins Leonardo La Serra Flavio P.Veras Daniele C.Nascimento Camila M.Silva Ricardo S.Cardoso Roberta Rosales Rogério Gomes Thais M.Lima Juliano P.Souza Brenda C.Vitti Diego B.Caetite Mikhael H.F.de Lima Spencer D.Stumpf Cassandra E.Thompson Louis-Marie Bloyet Juliana E Toller-Kawahisa Marcela C.Giannini Leticia P.Bonjorno Marial.F.Lopes Sabrina S.Batah Li Siyuan Rodrigo Luppino-Assad Sergio C.L.Almeida Fabiola R.Oliveira Maira N.Benatti Lorena L.F.Pontes Rodrigo C.Santana Fernando C.Vilar Maria Auxiliadora-Martins Pei-Yong Shi Thiago M.Cunha Rodrigo T.Calado JoséC.Alves-Filho Dario S.Zamboni Alexandre T.Fabro Paulo Louzada-Junior Rene D.R.Oliveira Sean P.J.Whelan Fernando Q.Cunha Eurico Arruda | 2022 | Journal of Molecular Cell Biology2022，14，4： | 1 |
| 6 | Oxide nanoparticle reservoirs for storage and prolonged release of corrosion inhibitors 显示文摘 | ZHELUDKEVICH M L SERRA Ricardo MONTEMOR M F | 2005 | Electrochem Commun2005，7，8： | 1 |
| 7 | 前庭诱发的肌源性电位在单侧前庭功能低下患者中的应用显示文摘目的:分析前庭诱发的肌源性电位(VEMP)在慢性头晕患者和单侧前庭功能低下患者中的表现,明确VEMP异常和病变侧别及受累结构的关系。方法:在本观察性研究中,我们对66例受试者进行了VEMP检查(短纯音刺激,强度100dB nHL,频率1 000Hz,带通滤波10~1 500Hz,刺激率4.3Hz)。根据临床表现和冷热试验,其中33例患者被诊断为单侧前庭功能低下,另外33例受试者为年龄性别匹配的对照。分析p13-n23的振幅、不对称率、潜伏期、耳间差异和阈值。统计学分析采用t检验,Shapiro-Wilks检验和Mann-Whitney检验,P<0.05有统计学意义。结果:63.63%的慢性前庭功能低下的患者存在VEMP异常,其中13例患者VEMP异常出现在前庭功能低下侧,3例患者出现在病变对侧。5例患者双侧VEMP异常。结论:冷热试验诊断为单侧慢性前庭功能低下的患者中,63.63%存在不同程度的VEMP的改变。54.54%的患者VEMP异常出现在前庭功能低下侧,24.24%的患者的VEMP异常出现在病变对侧。VEMP能够增强对单侧前庭功能低下患者的功能评价。 | ANA PAULA SERRA RICARDO SCHAFFELN DORIGUETO ROBERTA RIBEIRO DE ALMEIDA FERNANDO FREITAS GANACA 张甦琳 孔维佳 | 2013 | 临床耳鼻咽喉头颈外科杂志2013，27，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员