|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation显示文摘AIM To explore the expression of perform andgranzyme B genes mRNA to judge the effect ofimmunosuppression in acute rejection of livertransplantation.METHODS The expression of perform andgranzyme B genes mRNA was examined byreverse transcriptase-polymerase chain reaction(RT--PCR) in hamster to rat liver grafts under theimmunosuppression of cyclosporine or/andsplenectomy. Histological findings were studiedcomparatively.RESULTS Cyclosporine could obviouslydecrease the cellular infiltration, and completelyrepress the expression of mRNA for perform andgranzyme B, but could not change severehepatocyte necrosis and hemorrhage.SPlenectomy could significantly lightenhepatocyte necrosis, and completely eliminatehemorrhage, but not atfect the cellularinfiltration and the expression of perform andgranzyme B genes mRNA. Cyclosporine orsplenectomy alone could not prolong theSurvival time, however, their combination couldcompletely repress the rejection of liver grafts.The survival time of animals were significantlyprolonged (37.1 days ). The architecture ofhepatic lobules was preserved. There was slightcellular infiltration in the portal tracts and noexpression of perform and granzyme B genesmRNA could be seen in three weeks aftertransplantation.CONCLUSION Perform and granzyme B genesare valuable in judging the effect ofimmunosuppression in liver transplantation. | Zhang SG Wu MC Tan JW Chen H Yang JM Qian QJ | 1999 | World Journal of Gastroenterology1999，5，3： | 15 |
| 2 | 朊蛋白病诊断标志分子14-3-3Zeta基因亚克隆及其表达显示文摘目的 为了制备朊蛋白病特异性实验诊断的标志物及为探讨 14- 3 - 3在神经细胞功能调节中的作用创造条件。方法 根据 14- 3- 3Zeta亚型基因序列设计引物 ,扩增DNA片段 ,经酶切纯化后连接到pCYB3表达载体 ,转化大肠杆菌BL2 1菌株 ,用培养基筛选 ,经管状凝胶电泳纯化融合蛋白。结果与结论 获取了 14- 3- 3/pCYB3阳性重组体 ,经IPTG诱导及免疫印迹 -增强化学发光 (Westernblot-ECL)鉴定 ,表达出 14- 3- 3/intein -CBD融合蛋白 ,分子量为 82 7kDa . | 沈继龙 SG CHEN | 2000 | 中国人兽共患病杂志2000，16，5： | 4 |
| 3 | Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease显示文摘 | Aliyev A Chen SG Seyidova D | 2005 | J Neurol Sci2005，15，： | 1 |
| 4 | Intermittent pneumatic compression devices -- physiological mechanisms of action显示文摘 | Chen AH Frangos SG Kilaru S | 2001 | Eur J Vasc Endovasc Surg2001，21，5： | 1 |
| 5 | Protective effects of Ginkgo biloba extract on rats during cerebral ischemia/reperfusion显示文摘 | Sun SG Mei GW Chen LY Tong ET | 2002 | Chin Med J2002，115，9： | 1 |
| 6 | Intermittent watt -level ultrasonica- tion facilitates vaneomycin release from therapeutic acrylic bone ce- ment显示文摘 | Cai XZ Chen XZ Yan SG et o2 | 2009 | J Biomed Mater Res B Appl Biomater2009，1，： | 1 |
| 7 | Clinical and the prognostic characteristics of lung adenocarcinoma patients with ROS1 fusion in comparison with other driver mutations in East Asian populations显示文摘 | Chen YF Hsieh MS Wu SG | 2014 | J Thorac Oncol2014，9，8： | 1 |
| 8 | A novel senescence-associated gene encoding 'y-arninobutyric acid (GABA) : pyruvate trans- aminase is upregulated during rice leaf senescence显示文摘 | Ansari MI Lee R Chen SG | 2005 | Phys- iologia Plantarum2005，123，1： | 1 |
| 9 | Effects of aging on changing arterial compliance and left ventricalar load in a northern a Chinese urban community 显示文摘 | Avolio AP Chen SG Wang RP | 1983 | Circulation1983，68，： | 1 |
| 10 | Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat显示文摘 | Joseph E Chen X Khasar SG | 2004 | Pain2004，107，12： | 1 |
| 11 | Protective effects of an adenosine deaminase inhibitor on ischemia-reperfusion injury in isolated perfused rat heart显示文摘 | Zhu QY Chen SG Zou CM | 1990 | Am J Physiol1990，259，32： | 1 |
| 12 | Metabolic evolution of Corynebacterium glutamicum for increased production of L-ornithine显示文摘 | Jiang LY Chen SG Zhang YY | 2013 | BMC Biotechnology2013，13，： | 1 |
| 13 | Six weeks physical exercise im- proves obesity-associated hyperactivation of renin-angioten- sin system in obese children显示文摘 | Chen W Li SG Zhao HE | 2014 | J Am Coll Cardiol2014，24，16： | 1 |
| 14 | Proteetive effect of free radieal inhibitors in intraeerebral hemorrhage in rat显示文摘 | Peeling J Yah HJ Chen SG | 1998 | Brain Res1998，795，： | 1 |
| 15 | A dye release assay for determination oflysostaphin activity 显示文摘 | Zhou RQ Chen SG Recsei P | 1988 | Anal biochem1988，171，： | 1 |
| 16 | Regulated expression of surface AMPA receptors reduces excitotoxicity in auditory neurons显示文摘 | Chen Z Peppi M Kujawa SG | 2009 | JNeurophysiol2009，102，2： | 1 |
| 17 | Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease 显示文摘 | Aliyev A Chen SG Seyidova D | 2005 | J Neurol Sci2005，15，30： | 1 |
| 18 | The role of acupoint stimulation as an adjunct therapy for lung cancer:a systematic review and meta-analysis显示文摘 | Chen HY Li SG Cho WC | 2013 | BMC Complement Alternat Med2013，13，： | 1 |
| 19 | Serum CA242, CA199, CA125, CEA, and TSGF are biomarkers for the efficacy and prognosis of cryoablation in pancreatic cancer patients显示文摘 | Chen Y Gao SG Chen JM | 2014 | Cell Biochem Biophys2014，13，2： | 1 |
| 20 | Critical molecular pathways incancer stem cells of chronic myeloid leukemia 显示文摘 | Chen YY Peng C Li SG | 2010 | Leukemia2010，24，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员