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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Increased cadmium and lead uptake of a cadmium hyperaccumulator tomato by cadmium-resistant bacteria 显示文摘 | HE L Y CHEN A J REN G D ZHANG Y F QIAN M SHENG X F | 2009 | Ecotoxicology and Environmental Safety2009，72，： | 1 |
| 3 | Molecular evolution and functional specialization of chalcone synthase superfamily from Phalaenopsis orchid显示文摘 | Han Y Y Ming F Wang W Wang J W Ye M M Sheng D L | 2006 | Genetica2006，128，123： | 1 |
| 4 | Two-dimensional code application in agricultural Traceability 显示文摘 | SHENG L M WEI X T | 2013 | Modem Agricultural Science and Technology2013，，18： | 1 |
| 5 | Simultaneous bone marrow and tissue transplantation in rats treated with a nonmyeloablative conditioning regimen promote tolerance to composite tissue allngrafts显示文摘 | Ramsey D M Bozulie L D Sheng L W | 2009 | Immunology2009，182，141： | 1 |
| 6 | Distribution and enrichment of heavy metals among sediments, water body and plants in Hengshuihu Wetland of Northern China 显示文摘 | ZHANG M Y CUI L J SHENG L X | 2009 | Ecological Engineering2009，35，4： | 1 |
| 7 | EXAFS study of the interfacial interaction of nickel ( Ⅱ ) on titanate nanotubes: Role of contact time, pH and humic substances 显示文摘 | Sheng G D Ye L Li Y M | 2014 | Chemical Engineering Journal2014，248，： | 1 |
| 8 | Transplantation of stromal vascular fraction as an alternative for accelerating tissue expansion显示文摘 | Sheng L Yang M Du Z | 2013 | J Plast Reconstr Aesthet Surg2013，66，4： | 1 |
| 9 | Antioxidation of flavonoids of Green Rhizome显示文摘 | Kaijv M Sheng L Chao C | 2006 | Food Science2006，27，： | 1 |
| 10 | Distribution and enrichment of heavy metals among sediments, water body and plants in Hengshuihu Wetland of Northern China 显示文摘 | ZHANG M Y CUI L J SHENG L X | 2009 | Ecological Engineering2009，35，： | 1 |
| 11 | A refined model for base-isolated bridges with bi-linear hysteretic bearings 显示文摘 | J M Chiou L H Sheng J H | 1996 | Earthquake Spectra1996，12，2： | 1 |
| 12 | The classical progesterone receptor mediates Xenopus oocyte matu- ration through a nongenomic mechanism 显示文摘 | Bayaa M Booth R A Sheng Y L | 2000 | Proceed- ings of the National Academy of Sciences2000，97，12： | 1 |
| 13 | Rhodamine-based derivatives for Cu2+sensing:spectroscopic studies,structure-recognition relationships and its test strips显示文摘 | Yang Y X Gao W L Sheng R L Wang W L Liu H Yang W M Zhang T Y Zhang X T | 2011 | Spectrochimica Acta Part A2011，81，： | 1 |
| 14 | Characterization of adsorption properties of extraeellular polymeric substances (EPS) extracted from sludge显示文摘 | Sheng G P Zhang M L Yu H Q | 2008 | Colloids and Surfaces B: Biointerfaces2008，62，1： | 1 |
| 15 | Effects of nitrate supply on plant growth, nitrate accumulation, metabolic nitrate concentration and nitrate reductase activity in three leafy vegetables显示文摘 | Chen B M Zhao H W Sheng X L | 2004 | Plant Science2004，167，3： | 1 |
| 16 | Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gra- vis 显示文摘 | Thiruppathi M' Sheng JR Li L | 2014 | J Autoimmun2014，42，： | 1 |
| 17 | FeOOH catalytic ozonafion of oxalic acid and the effect of phosphate binding on its catalytic activity显示文摘 | Sui M H Sheng L Lu K X | 2010 | Applied Catalysis B:Environment2010，96，： | 1 |
| 18 | Mismatch repair gene mutations in Chinese HNPCC patients显示文摘 | Sheng J Q Fu L Sun Z Q Huang J S Han M Mu H Zhang H Zhang Y Z Zhang M Z Li A Q Wu Z T Han Y Li S R | 2008 | Cytogenetic and Genome Research2008，，1： | 1 |
| 19 | Fe OOH catalytic ozonation of oxalic acid and the effect of phosphate binding on its catalytic activity显示文摘 | Sui M H Sheng L Lu K X | 2010 | Appl Catal B:Environ2010，96，12： | 1 |
| 20 | Pyrrolizidine alkaloid clivo- rine induces apoptosis in human normal liver L -02 cells and re- duces the expression of p53 protein显示文摘 | JI L L ZHANG M SHENG Y C | 2005 | Toxicol In Vitro2005，19，1： | 1 |
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