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| 1 | A nodule dome removal strategy to improve the laser-induced damage threshold of coatings显示文摘Various coatings in high-power laser facilities suffer from laser damage due to nodule defects.We propose a nodule dome removal(NDR)strategy to eliminate unwanted localized electric-field(E-field)enhancement caused by nodule defects,thereby improving the laser-induced damage threshold(LIDT)of laser coatings.It is theoretically demonstrated that the proposed NDR strategy can reduce the localized E-field enhancement of nodules in mirror coatings,polarizer coatings and beam splitter coatings.An ultraviolet(UV)mirror coating is experimentally demonstrated using the NDR strategy.The LIDT is improved to about 1.9 and 2.2 times for the UV mirror coating without artificial nodules and the UV mirror coating with artificial nodule seeds with a diameter of 1000 nm,respectively.The NDR strategy,applicable to coatings prepared by different deposition methods,improves the LIDT of laser coating without affecting other properties,such as the spectrum,stress and surface roughness,indicating its broad applicability in high-LIDT laser coatings. | Tianbao Liu Meiping Zhu Wenyun Du Jun Shi Jian Sun Yingjie Chai Jianda Shao | 2022 | High Power Laser Science and Engineering2022，10，5： | 2 |
| 2 | The pinhole SPECT for animal model of bone metastasis with SPC-A-1BM human pulmonary adenocarcinoma bone metastasis cell line显示文摘The study was to investigate the role of pinhole single photon emission computed tomography (SPECT), the human pulmonary adenocarcinoma bone-seeking metastasis cell line SPC-A-1BM was used.These cells form typical osteolytic bone metastases when inoculated into the arterial circulation of NIH-Beige-Nude-XD (BNX) mice via the left ventricle.In order to evaluate the irradiation impact of ^(99m)Tc-MDP versus X-ray on cells growth,we used six groups of SPC-A-1BM cells in our imaging scheme and irradiated by various doses of ^(99m)Tc-MDP (37,74,111, 370,740 MBq) and X-ray(40 kV,2 mA,6 s) respectively.The cell's number of each group was well recorded in different exposure time(4,8,12,24,48,72,96 hours).After that,SPC-A-1BM cells(1×106) were inoculated into the mice via left ventricle.We compared the results obtained with those different doses of ^(99m)Tc-MDP using pinhole SPECT and conventional X-ray skeletal surveys.The data show that the cell-survival number of 111 MBq group has insignificant difference with that of X-ray and the dose is adequate to have an ideal image.Besides,it is important that the chromosome of the cells in the group of 111 MBq showed no irradiation-related damages in our test.These results implied that ^(99m)Tc-MDP pinhole SPECT may provide another way other than conventional X-ray skeletal surveys in detecting bone metastasis of pulmonary adenocarcinoma in BNX mice. | GAO Xiuli YANG Shunfang YU Yongli SHI Meiping ZHAO Lanxiang YE Jianding LU Jianying | 2008 | Nuclear Science and Techniques2008，19，5： | 1 |
| 3 | Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by 99m Tc-MDP bone scintigraphy显示文摘 | Shunfang Yang Qianggang Dong Ming Yao Meiping Shi Jianding Ye Langxiang Zhao Jianzhong Su Weiyong Gu Wenhui Xie Kankan Wang Yanzhi Du Yao Li Yan Huang | 2009 | Nuclear Medicine and Biology2009，，3： | 1 |
| 4 | Effect of subsurface impurity defects on laser damage resistance of beam splitter coatings显示文摘The laser-induced damage threshold(LIDT)of plate laser beam splitter(PLBS)coatings is closely related to the subsurface absorption defects of the substrate.Herein,a two-step deposition temperature method is proposed to understand the effect of substrate subsurface impurity defects on the LIDT of PLBS coatings.Firstly,BK7 substrates are heat-treated at three different temperatures.The surface morphology and subsurface impurity defect distribution of the substrate before and after the heat treatment are compared.Then,a PLBS coating consisting of alternating HfO2–Al2O3 mixture and SiO2 layers is designed to achieve a beam-splitting ratio(transmittance to reflectance,s-polarized light)of approximately 50:50 at 1053 nm and an angle of incidence of 45◦,and it is prepared under four different deposition processes.The experimental and simulation results show that the subsurface impurity defects of the substrate migrate to the surface and accumulate on the surface during the heat treatment,and become absorption defect sources or nodule defect seeds in the coating,reducing the LIDT of the coating.The higher the heat treatment temperature,the more evident the migration and accumulation of impurity defects.A lower deposition temperature(at which the coating can be fully oxidized)helps to improve the LIDT of the PLBS coating.When the deposition temperature is 140◦C,the LIDT(s-polarized light,wavelength:1064 nm,pulse width:9 ns,incident angle:45◦)of the PLBS coating is 26.2 J/cm2,which is approximately 6.7 times that of the PLBS coating deposited at 200◦C.We believe that the investigation into the laser damage mechanism of PLBS coatings will help to improve the LIDT of coatings with partial or high transmittance at laser wavelengths. | Wenyun Du Meiping Zhu Jun Shi Tianbao Liu Jian Sun Kui Yi Jianda Shao | 2023 | High Power Laser Science and Engineering2023，11，5： | 0 |
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