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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 3 | Regulation of the osmotin gene promoter 显示文摘 | Kononowicz K Nelson D E Singh N K | 1992 | Plant Cell1992，，4： | 2 |
| 4 | CFTR activation raises extracellular pH of NIH/3T3 mouse fibroblasts and C127 epithelial cells显示文摘 | Luckie D B Singh C N Wine J J | 2001 | J Membr Biol2001，179，3： | 2 |
| 5 | Lipid-Rich Variant of Pancreatic Endocrine Neoplasms显示文摘 | Rajendra Singh Olca Basturk David S Klimstra Giuseppe Zamboni Runjan Chetty Sanaa Hussain Stefano La Rosa Asli Yilmaz Paola Capelli Carlo Capella Jeanette D Cheng N Volkan Adsay | 2006 | The American Journal of Surgical Pathology2006，，2： | 2 |
| 6 | Aspergillus infections in transplant recipients 显示文摘 | Singh N Paterson D L | 2005 | Clin Microbiol Rev2005，18，1： | 1 |
| 7 | Role of angiotensin Ⅱ in diabetic nephropathy显示文摘 | Leehey D J Singh A K Alavi N | 2000 | Kidney Int2000，，： | 1 |
| 8 | Transforming growth factor-beta-regulated expression of genes in macrophages implicated in the control of cholesterol homoeostasis 显示文摘 | Ramji D P Singh N N Foka P | 2006 | Bioehem Soc Trans2006，34，6： | 1 |
| 9 | A simple tech- nique for quantitation of low levels of DNA damage in indi-vidual cells 显示文摘 | Singh N P McCoy M T Tice R R et d | 1988 | Experimental Cell Research1988，175，1： | 1 |
| 10 | Aluminum phosphide ingestiona dinico - pathologic study 显示文摘 | Singh S Singh D Wig N | 1996 | J Toxicol1996，34，7： | 1 |
| 11 | High-performance liquid chromatographic analysis of ampho-tericin B in rat plasma using α-naphthol as an internal standard显示文摘 | ITALIA J L SINGH D KUMAR M N V R | 2009 | Anal Chim Acta2009，634，1： | 1 |
| 12 | Nonlinear predictive control of feedback linearizable systems and flight control system design显示文摘 | Singh Sahjendra N Steinberg M Digirolamo R D | 1995 | Journal of Guide Cont and Dynamias1995，18，5： | 1 |
| 13 | Plant-made vaccine antigens and biopharmaceuticals显示文摘 | Daniell H Singh N D Mason H | 2009 | Trends Plant Sci2009，14，12： | 1 |
| 14 | Strategies to deal with the concern about marker genes in transgenic plants:some environment-friendly approaches显示文摘 | Jaiwal P K Sahoo L Singh N D | | 0，，02： | 1 |
| 15 | Antioxidant and free radical scavenging activities of phenols from onion (AUium cepa) 显示文摘 | PRAKASH D SINGH B N UPADHYAY G | 2007 | Food Chemistry2007，102，4： | 1 |
| 16 | Regulation of the osmotin gene promoter 显示文摘 | KONONOWICZ K NELSON D E Singh N K | 1992 | Plant Cell1992，，4： | 1 |
| 17 | Allelopathic effects of weeds on germination and seedling growth of maize and soybean显示文摘 | SINGH S D SINGH C M | 1988 | Indian J Weed Sci1988，20，2： | 1 |
| 18 | Role of angiotensin Ⅱ in DN显示文摘 | Leehey D J Singh A K Alavi N | 2000 | Kidney Int2000，58，： | 1 |
| 19 | Ameliorative effects of Ocimum sanctum in sciatic nerve transection-induced neuropathy in rats显示文摘 | Muthuraman A Diwan V Jaggi AS Singh N Singh D | 2008 | J Ethnopharmacol2008，120，1： | 1 |
| 20 | Reduction of Cr (VI) under acidic conditions by the facuhative Fe(III)-re- ducing bacterium A cidiphilium cryptum显示文摘 | CUMMINGS D E FENDORF S SINGH N | 2007 | Environmental Sci- ence & Technology2007，41，1： | 1 |
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