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| 1 | Prognostic efficacy of inflammation-based markers in patients with curative colorectal cancer resection显示文摘AIM To evaluate the prognostic significance of neutrophilto-lymphocyte ratio(NLR), platelet-to-lymphocyte ratio(PLR), lymphocyte-to-monocyte ratio(LMR), and prognostic nutritional index(PNI) and other clinicopathological factors in patients undergoing curative resection of colon cancer.METHODS183 patients with histologically proven colorectal cancer who had undergone potentially curative resection between 2010 and 2016 at Ankara Numune Training and Research Hospital were retrospectively analyzed and clinicopathological characteristics included age, sex, tumor type, grade, size and localization, the number of metastatic and total number of lymph nodes removed, vascular and perineural invasion of the tumor, TNM stages, tumor marker levels(CEA, CA19-9, AFP, CA-125, CA15-3), complete blood counts, albumin levels, overall survival(months), NLR, PLR, LMR and PNI ratios were retrospectively reviewed and analyzed from the electronic database. The primary outcome measure was overall survival.RESULTS Regarding overall survival, on univariate analysis the following variables were significantly associated with poor outcome following resection: T-stage(P = 0.037), lymph node invasion(P = 0.037), cancer stage(P = 0.034), CEA(P = 0.042), CA19-9(P = 0.004), and PNI(P = 0.001). To evaluate the independent prognostic value, multivariate Cox proportional hazard analysis to control for other prognostic factors was used. Using cancer-specific death as an end point for NLR, PLR, LMR, PNI and CA19-9 the optimal cut off values were calculated by ROC analysis. Regarding overall survival, on multivariate analysis high CA19-9(HR = 1.001, 95%CI: 1.00-1.002, P = 0.012) and low PNI(HR = 0.938, 95%CI: 0.891-0.987, P = 0.014) were the only variables independently associated with shortened overall survival. Patients with a PNI < 35 had a median OS of 52.25 mo. In contrast, patients with an PNI > 35 had a median OS of 66 mo. Patients with a CA 19-9 < 17 had a median OS of 66 mo and in patients with a CA19-9 > 17 had a median OS of 53.76 mo.CONCLUSION This study shows that decrease in the PNI and increase in CA 19-9 is associated with poor survival in patients with resectable colon cancer. | özgür Akgül Erdinc Cetinkaya Metin Yalaza Sabri özden Mesut Tez | 2017 | World Journal of Gastrointestinal Oncology2017，9，7： | 11 |
| 2 | Biological subtypes of breast cancer: Prognostic and therapeutic implications显示文摘Breast cancer is a heterogeneous complex of diseases, a spectrum of many subtypes with distinct biological features that lead to differences in response patterns to various treatment modalities and clinical outcomes. Traditional classification systems regarding biological characteristics may have limitations for patient-tailored treatment strategies. Tumors with similar clinical and pathological presentations may have different behaviors. Analyses of breast cancer with new molecular techniques now hold promise for the development of more accurate tests for the prediction of recurrence. Gene signatures have been developed as predictors of response to therapy and protein gene products that have direct roles in driving the biology and clinical behavior of cancer cells are potential targets for the development of novel therapeutics. The present review summarizes current knowledge in breast cancer molecular biology, focusing on novel prognostic and predictive factors. | Ozlem Yersa L Sabri Barutca | 2014 | World Journal of Clinical Oncology2014，5，3： | 10 |
| 3 | A multicenter randomized con-trolled trial comparing single-row with double-row fixation in ar-throscopic rotator cuff repair显示文摘 | Lapner P L Sabri E Rakhra K | 2012 | J Bone Joint Surg Am2012，94，14： | 1 |
| 4 | Mineralogy of compacted clay-lime mixtures显示文摘 | SABRY M A REED L W JPARCHE R V | 1981 | Soil Science Society of America Journal1981，45，1： | 1 |
| 5 | Relating circulating thyroid hormone concentrations to serum interleuklns- 6 and-lO in association with non-thyroidal illnesses including chronic renal insufficiency显示文摘 | Abo-Zenah HA Shoeb SA Sabry AA l | 2008 | BMC Endocr Disord2008，8，： | 1 |
| 6 | A study on the influence of bond material on honing engine cylinder bores with coated diamond stones显示文摘 | Sabri L Mezghani S El Mansori M | 2010 | Surface and Coatings Technology2010，205，5： | 1 |
| 7 | Biologicalactivities of sulfated polysaccharides from tropical seaweeds显示文摘 | Costa L S Fidelis G P Cordeiro S L R M Oliveira D A Sabry R B G CSmara L T D B Nobre MSS PCosta J Almeida-Lima E H C Farias E L Leite H A 0 Rocha | 2010 | Biomedicine & Pharmacotherapy2010，64，1： | 1 |
| 8 | Process variability in honing of cylinder liner with vitrified bonded diamond tools 显示文摘 | Sabri L Mansori El M | 2009 | Surface and Coatings Technology2009，204，67： | 1 |
| 9 | Myosin dynamics in live dictyostelium cells显示文摘 | Moores S L Sabry J H Spudich J A | 1996 | Proc Natl Acad Sci USA1996，93，1： | 1 |
| 10 | Osmoregulation in sp ringwheat under drought and salinity stress显示文摘 | Sabry S R S Smith L T Smith GM | 1995 | Journal of Genetics &Breeding1995，49，1： | 1 |
| 11 | Osmoregulation in spring wheat under drought and salinity stress显示文摘 | Sabry S R S Smith L T Smith G M | 1995 | Journal of Genetics & Breeding1995，49，1： | 1 |
| 12 | Myosin dynamics in live Dictyostelium cells显示文摘 | Moores S L Sabry J H Spudich J A | 1996 | Proc Natl Acad Sci USA1996，93，1： | 1 |
| 13 | Graphenefield effect transistors with parylene gate dielectric显示文摘 | Sabri S S Levesque P L Aguirre C M | 2009 | Applied Physics Letters2009，95，24： | 1 |
| 14 | Sulfation of the extracellular polysaccharide produced by the edible mushroom Pleurotns sajor-caju alters its antioxidant, anticoagulant and antiproliferative properties in vitro显示文摘 | TELLES C B S SABRY D A JAILMA A L | 2011 | Carbohydrate Polymers2011，85，3： | 1 |
| 15 | Could platelet distribution width be a predictive marker for unexplained recurrent miscarriage?显示文摘 | ülkü Mete Ural Ye?im Bayo?lu Tekin Gül?ah Balik Figen Kir ?ahin Sabri ?olak | 2014 | Archives of Gynecology and Obstetrics2014，，2： | 1 |
| 16 | Osmoregulation in spring wheat under drought and salinity stress 显示文摘 | Sabry S R S Smith L T Smith G M | 1995 | Journal of Genetics & Breeding1995，49，1： | 1 |
| 17 | Web-based learning interaction and learning styles 显示文摘 | Sabry K Baldwin L | 2003 | British Journal of Educational Technology2003，34，4： | 1 |
| 18 | Controlling of degradation effects in radiation processing of starch显示文摘 | KAMAL H SABRY G M SALAH L | 2007 | Journal of Macromolecular Science PartA:Pureand Applied Chemistry2007，44，7： | 1 |
| 19 | Osmoregulation in spring wheat under drought and salinity显示文摘 | Sabry S R Smith L T Smith G M | 1995 | Journal of Genetics & Breeding1995，49，1： | 1 |
| 20 | SwingsApplication of multilocus sequence analysis (MLSA) for rapid identification of Ergerococcus species based on rpoA and pheS genes 显示文摘 | SABRI M NASER FABIANO L THOMPSON BART HOSTE | 2005 | Microbiology2005，151，： | 1 |
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