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| 1 | Omental flaps reduces complications after pancreaticoduodenectomy显示文摘BACKGROUND:Major complications after pancreaticoduodenectomy are usually caused by a leaking pancreaticojejunal anastomosis.Omental flaps around various anastomoses were used to prevent the formation of fistula.METHODS:We reviewed 147 patients who had undergone pancreaticoduodenectomy between March 2006 and March2012.The patients were divided into 2 groups according to the application of omental flaps around various anastomoses:group A(101 patients)who underwent omental wrapping procedure;group B(46 patients)who did not undergo the omental wrapping procedure.Perioperative data of the two groups were reviewed to assess the effectiveness of omental flap procedure in the prevention of pancreatic fistula and other complications.RESULTS:No differences were observed in the clinical characteristics between the 2 groups.The incidences of pancreatic fistula(4.0%vs 17.4%),post-pancreatectomy hemorrhage(0vs 6.5%),biliary fistula(1.0%vs 13.0%),and delayed gastric emptying(4.0%vs 17.4%)were significantly less frequent in group A.The overall morbidity(18.8%vs 47.8%)and hospital stay(8.3 vs 9.6 days)were also significantly lower in group A than in group B.CONCLUSIONS:Omental flaps around various anastomoses after pancreaticoduodenectomy can reduce the incidences of pancreatic fistula,biliary fistula,post-pancreatectomy hemorrhage and delayed gastric emptying.This procedure is simple and effective to reduce the overall morbidity after pancreaticoduodenectomy. | Omar J Shah Sadaf A Bangri Manmohan Singh Reyaz A Lattoo Mohammad Y Bhat | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，3： | 19 |
| 2 | Complications and survival in patients undergoing colonic stenting for malignant obstruction显示文摘AIM:To investigate whether predicting patients that might be at a higher risk for complications might serve to improve the selection of patients undergoing colonic stenting.METHODS:A retrospective review of consecutive patients who underwent an attempted self-expandable metal stent(SEMS)insertion for malignant colonic obstruction between November 2006 and March 2013.All patients were either referred for preoperative colonic decompression with the intent of a single surgical procedure,or for palliation of the malignant colorectal obstruction for unresectable cancer.Fisher’s test orχ2test was performed on categorical variables,and the t test for continuous variables.Univariable and multivariable logistic regression were used to examine the association between independent variables and the presence of complications from SEMS insertion.RESULTS:SEMS insertion was attempted in 73 patients.Males comprised 55.71%and the mean age was 67.41±12.41 years.Of these,65.15%underwent subsequent surgery,while 34.85%received SEMS as palliation for advanced disease.Extracolonic tumors were only4.76%.The majority of patients had stageⅣdisease(63.83%),while the remainder had stageⅢ(36.17%).SEMS were successfully inserted in 93.85%(95%CI:87.85%-99.85%).Perforations occurred in 4.10%,SEMS migration in 8.21%,and stent re-occlusion from ingrowth occurred in 2.74%of patients.The mean duration of follow up for the patients was 13.52±17.48 mo(range 0-73 mo).None of the variables:age,sex,time between the onset of symptoms to SEMS insertion,time between SEMS insertion and surgery,length of the stenosis,location of the stenosis,albumin level,or receiving neoadjuvant chemotherapy,could predict the development of complications from either SEMS insertion nor prolonged survival.CONCLUSION:None of the variables could predict the development of complications or survival.Further studies are required to identify patients who would benefit the most from SEMS. | Majid A Almadi Nahla Azzam Othman Alharbi Alabbas H Mohammed Nazia Sadaf Abdulrahman M Aljebreen | 2013 | World Journal of Gastroenterology2013，19，41： | 5 |
| 3 | A selective approach to the surgical management of periampullary cancer patients and its outcome显示文摘BACKGROUND: Pancreaticoduodenectomy is a high risk, complex, technically challenging operation associated with significant perioperative morbidity and mortality. This study on the surgical management of periampullary cancer patients is based on our experience in a period of nearly 13 years.METHODS: The study was conducted on two groups of patients: group A included 42 patients who were treated between January 2000 and September 2005 and group B included 134 patients who were treated between October 2005 to October 2012. Preoperative, intraoperative and postoperative details of all these patients were collected, tabulated and analyzed to assess the impact of the selective approach introduced in the department with effect from October 2005.RESULTS: Intraoperative details revealed highly significant differences in the management of the two groups of patients in respect of operative time (250.4 vs 126.6 minutes; P<0.001), operative blood loss (1070.2 vs 414.9 m L; P<0.001) and intraoperative blood transfusion (1.4 vs 0.2 units; P<0.001). Variations between the two groups in the frequency of complications were found to be statistically insignificant. However, the difference between the two groups in the overall morbidity of patients (47.6% vs 26.1%; P=0.009) and the length of their hospital stay (11.8 vs 7.8 days; P<0.001) were significant.CONCLUSION: A selective approach applied to the surgical management of periampullary cancer patients is a step in the right direction. | Omar J Shah Irfan Robbani Parveen Shah Sadaf A Bangri Irfan J Khan Mohammad Y Bhat Manmohan Singh | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 3 |
| 4 | Clinical epidemiology of ulcerative colitis in Arabs based on the Montréal classification显示文摘AIM:To determine the clinical,epidemiological and phenotypic characteristics of ulcerative colitis(UC)in Saudi Arabia by studying the largest cohort of Arab UC patients.METHODS:Data from UC patients attending gastroenterology clinics in four tertiary care centers in three cities between September 2009 and September 2013were entered into a validated web-based registry,inflammatory bowel disease information system(IBDIS).The IBDIS database covers numerous aspects of inflammatory bowel disease.Patient characteristics,disease phenotype and behavior,age at diagnosis,course of the disease,and extraintestinal manifestations were recorded.RESULTS:Among 394 UC patients,males comprised51.0%and females 49.0%.According to the Montréal classification of age,the major chunk of our patients belonged to the A2 category for age of diagnosis at17-40 years(68.4%),while 24.2%belonged to the A3category for age of diagnosis at>40 years.According to the same classification,a majority of patients had extensive UC(42.7%),35.3%had left-sided colitis and29.2%had only proctitis.Moreover,51.3%were in remission,16.6%had mild UC,23.4%had moderate UC and 8.6%had severe UC.Frequent relapse occurred in17.4%patients,infrequent relapse in 77%and 4.8%had chronic disease.A majority(85.2%)of patients was steroid responsive.With regard to extraintestinal manifestations,arthritis was present in 16.4%,osteopenia in 31.4%,osteoporosis in 17.1%and cutaneous involvement in 7.0%.CONCLUSION:The majority of UC cases were young people(17-40 years),with a male preponderance.While the disease course was found to be similar to that reported in Western countries,more similarities were found with Asian countries with regards to the extent of the disease and response to steroid therapy. | Othman R Alharbi Nahla A Azzam Ahmed S Almalki Majid A Almadi Khalid A Alswat Nazia Sadaf Abdulrahman M Aljebreen | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 5 | Performance of comput-er-aided detection applied to full-field digital mammography indetection of breast cancers显示文摘 | Sadaf A Crystal P Scaranelo A | 2011 | Eur J Radiol2011，77，： | 1 |
| 6 | Investigation of some oleochemicals as green inhibitors on mild steel corrosion in sulfuric acid显示文摘 | Rafiquee M Z A Khan Sadaf Saxena Nidhi | 2009 | Appl Electrochem2009，39，8： | 1 |
| 7 | Production enhancement and refolding of caprine growth hormone expressed in Eschcri<'hia col i显示文摘 | Khan M A Sadaf S Sajjad M | 2009 | Protein expression and purification2009，68，1： | 1 |
| 8 | Toxicity evaluation of hydrophilic CdTe quantum dots and CdTe@ SiO2 nanoparticles in mice 显示文摘 | Sadaf A Zeshan B Wang Z | 2012 | J Nanosci Nanotechnol2012，12，11： | 1 |
| 9 | Performance of computer- aided detection applied to full-field digital mammography in de tection of breast cancers显示文摘 | Sadaf A Crystal P Scaranelo A | 2011 | Eur J Radiol2011，77，3： | 1 |
| 10 | Production of Sporotrichum thermophilexylanase by solid state fermentation utilizing deoiled Jat rophacurcas seed cake and its application in xylooligosachharide synthesis显示文摘 | Sadaf A Khare SK | 2014 | Bioresource Technology2014，153，2： | 1 |
| 11 | Obscure gastrointestinal bleed from a gastrointestinal stromal tumor in a jejunal diverticu- lum: a rare case report显示文摘 | Sadaf A Sunil D Athar B Khalid B | 2010 | Case Rep Oncol2010，3，1： | 1 |
| 12 | Primary ovarian lymphoma--a rare entity显示文摘 | Afshan A Sadaf N | 2013 | J Pak Med Assoc2013，63，4： | 1 |
| 13 | Performance of computer-ai- ded detection applied to full-field digital mammography in detectition of breast cancers显示文摘 | Sadaf A Crystal P Searanelo A | 2011 | Eur J Radiol2011，77，3： | 1 |
| 14 | Primary ovarian lymphoma-a rare entity显示文摘 | Afshan A Sadaf N | 2013 | Pak Med Assoc2013，63，4： | 1 |
| 15 | A comparative study of CdTe quantum dots and CdTe@SiO2 nanoparticles:fabrication and cytotoxicity in HEK293 cells显示文摘 | Sadaf A Zeshan B Wang Z Zhang R Xu S Wang C | | 0，，09： | 1 |
| 16 | Toxicity evaluation of hydrophilic CdTe quantum dots and CdTe@SiO2 nanoparticles in mice显示文摘 | Sadaf A Zeshan B Wang Z Zhang R Xu S Wang C | | 0，，11： | 1 |
| 17 | Apolipoprotein AI promoter variant in blood pressure determination显示文摘 | Sadaf A Siddiqui S Lestringant GG | 2002 | Clin Genet2002，61，4： | 1 |
| 18 | Influence of leptin on arterial distensility 显示文摘 | Sadaf Farooqi I Cole TJ | 2002 | Circulation2002，106，： | 1 |
| 19 | Role of MRI for staging of rectal cancer显示文摘 | Jhaveri KS Sadaf A | | 0，，： | 1 |
| 20 | Primary ovarian lymphoma-a rare entity显示文摘 | Afshan A Sadaf N | 2013 | J Pak Med Assoc2013，63，： | 1 |
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