维普中文期刊产品整合服务
27篇 您的检索式:作者名="Sadowski I"
    题名 作者 年代 出处 被引量
1Systematic use of recurrent laryngeal nerve neuromonitoring changes the operative strategy in planned bilateral thyroidectomy 显示文摘Sadowski SM Soardo P Leuchter I 2013Thyroid2013,23,3:1
2Biological synthesis of goldnanostructures using the extract of Trichoderma koningii 显示文摘Maliszewska I Sadowski Z 2009ActaPhysicaPolonicaA2009,,116:1
3Synthesis of silver nanoparticles using microorganisms 显示文摘Sadowski Z Maliszewska I Grochowalska B 2008Materials Science: Poland2008,26,2:1
4The effect of biopretreatment on the flotation recovery of magnesite tailings显示文摘Gawel J Maliszewska I Sadowski Z 1997Minerals Engineering1997,10,8:1
5A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of fujinami sarcoma virus p130GAG-FPS显示文摘Sadowski I Stone J C Pawson T 1986Molecular and Cellular Biology1986,6,:1
6The sequence structure relation-ship and protein function prediction显示文摘M I Sadowski D T Jones 2009Current Opinion in Structural Biology2009,19,3:1
7The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response显示文摘Bernhard W Barreto K Saunders A Dahabieh MS Johnson P Sadowski I 2011FEBS Lett2011,585,22:1
8Agglomerate flotation of fine oxide particles 显示文摘SADOWSKI Z POLOWCZYK I 2004International Journal of Mineral Processing2004,74,1:1
9An experimental investigation of micro- channel flow with internal pressure measurements显示文摘Kohl M J Abdel-Khalik S I Jeter S M Sadowski D L 2005International Journal of Heat and Mass Transfer2005,48,8:1
10pGenTHREAD- ER and pDomTHREADER: new methods for improved pro- tein fold recognition and superfamily discrimination 显示文摘LOBLEY A SADOWSKI M I JONES D T 2009Bioinformaties2009,25,14:1
11Left ventriculartrue aneurysm without coronary artery occlusion-a case study显示文摘Sadowski I Wierzbicki K Wojci kS 2002Przegl Lek2002,59,3:1
12Signaling from endosomes:Location makes a difference显示文摘Sadowski L Pilecka I Miaczynska M 2009Exp Cell Res2009,315,9:1
13Treatment of reverseoblique and transverse intertrochanlerie fraetures with use of anintramedullary nail of 95°serew-plate 显示文摘Sadowski C I ubbeke A Saudan M 2002J Bone Joint Surg(Br)2002,84,:1
14Wild type GAL4binds cooperatively to the GAL1-10 UASG in vitro显示文摘KANG T MARTINS T SADOWSKI I 1993JBiol Chem1993,268,13:1
15The effect of biopretreatment on the flotation recovery of magnesite tailings显示文摘Gawel J Maliszewska I Sadowski Z 1997Minerals Engineering1997,10,8:1
16Three-dimensional solution for the stress concentration around a circular hole in a plate of arbitrary thickness 显示文摘 Sadowsky M A Chicago I L L 1949J Appl Mech1949,16,1:1
17Multiple signals regulate GAL transcription in yeast显示文摘Rohde JR Trinh J Sadowski I 2000Molecular and Cellular Biology2000,20,11:1
18GAL4 is phos-phorylated as a consequence of transcriptional activation显示文摘SADOWSKI I NIEDBALA D WOOD K 1991ProcNatl Acad Sci USA1991,88,10:1
19GAIA-VP16 is an unusually potent transcriptional activator显示文摘Sadowski I Ma J Triezenberg S 1988Nature1988,335,6190:1
20Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation显示文摘AIM:To investigate genetic differences between Crohn's disease(CD) patients with a sustained remission vs relapsers after discontinuing infliximab while in corticosteroid-free remission.METHODS:Forty-eight CD patients received infliximab and were in full corticosteroid-free clinical remission but then discontinued infliximab for reasons other than a loss of response,were identified by review of an electronic database and charts.Infliximab-associated remission was defined as corticosteroid-free plus normalization of clinical disease activity [CD activity index(CDAI) < 150] during follow-up visits based on physician global assessments.A CD relapse(loss of infliximab-induced remission) was clinically defined as a physician visit for symptoms of disease activity(CDAI > 220) and a therapeutic intervention with CD medication(s),or a hospitalization with complications related to active CD.Genetic analyses were performed on samples from 14 patients(n = 6 who had a sustained long term remission after stopping infliximab,n = 8 who rapidly relapsed after stopping infliximab).Nucleotide-binding oligomerization domain 2(NOD2)/caspase activation recruitment domain 15(CARD15) polymorphisms(R702W,G908R and L1007fs) and the inflammatory bowel disease 5(IBD5) polymorphisms(IGR2060a1 and IGR3081a1) were analyzed in each group.RESULTS:Five single nucleotide polymorphisms of IBD5 and NOD2/CARD15 genes were successfully analyzed for all 14 subjects.There was no significant increase in frequency of the NOD2/CARD15 polymorphisms(R702W,G908R and L1007fs) and the IBD5 polymorphisms(IGR2060a1 and IGR3081a1) in either group of patients;those whose disease relapsed rapidly or those who remained in sustained long term remission following the discontinuation of infliximab.Nearly a third of patients in full clinical remission who stopped infliximab for reasons other than loss of response remained in sustained clinical remission,while two-thirds relapsed rapidly.There was a marked difference in the duration of clinical remission following discontinuance of infliximab between the two groups.The patients who lost remission did so after 1.0 years ± 0.6 years,while those still in remission were at the time of this study,8.1 years ± 2.6 years post-discontinuation of infliximab,P < 0.001.The 8 patients who had lost remission after discontinuing infliximab had a mean number of 5 infusions(range 3-7),with a mean treatment time of 7.2 mo(range 1.5 mo-15 mo).The mean duration of time from the last infusion of infliximab to the time of loss of remission was 382 d(range 20 d-701 d).The 6 patients who remained in remission after discontinuing infliximab had a mean number of 6 infusions(range 3-12),with a mean treatment duration of 12 mo(range 3.6 mo-32 mo)(P = 0.45 relative to those who lost remission).CONCLUSION:There are no IBD5 or NOD2/CARD15 mutations that predict which patients might have sustained remission and which will relapse rapidly after stopping infliximab.Cathy Lu Alistair Waugh Robert J Bailey Raeleen Cherry Levinus A Dieleman Leah Gramlich Kata Matic Mario Millan Karen I Kroeker Daniel Sadowski Christopher W Teshima Dennis Todoruk Clarence Wong Karen Wong Richard N Fedorak 2012World Journal of Gastroenterology2012,18,36:1
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费