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| 1 | 儿童功能性胃肠病罗马Ⅳ标准显示文摘罗马标准是目前关于功能性胃肠病( FGID)分类最全面且不断更新的标准。罗马Ⅰ、Ⅱ标准分别于1994年、1999年发布。罗马Ⅱ标准开始单列儿童FGID分类。2006年,根据年龄不同,婴幼儿(0-36个月)和儿童(〉36个月) FGID的罗马Ⅲ诊断标准发布,但相关的流行病学、病理生理学、诊断检查、治疗策略以及预后等资料都很少。 | Marc A. Benninga Samuel Nurko Christophe Faure Paul E. Hyman Ian St. James Roberts Neil L. Schechter Jeffrey S. Hyams Carlo Di Lorenzo Miguel Saps Robert J. Shulman Annamaria Staiano Miranda van Tilburg | 2017 | 中华儿科杂志2017,55,1: | 108 |
| 2 | Total hip arthroplasty for posttraumatic osteoarthritis following acetabular fracture: A systematic review of characteristics, outcomes, and complications显示文摘 | Robert D. Stibolt Jr. Harshadkumar A. Patel Samuel R. Huntley Eva J. Lehtonen Ashish B. Shah Sameer M. Naranje | 2018 | Chinese Journal of Traumatology2018,21,3: | 28 |
| 3 | Immuno-oncology combinations: raising the tail of the survival curve显示文摘There have been exponential gains in immuno-oncology in recent times through the development of immune checkpoint inhibitors. Already approved by the U.S. Food and Drug Administration for advanced melanoma and non-small cell lung cancer,immune checkpoint inhibitors also appears to have significant antitumor activity in multiple other tumor types. An exciting component of immunotherapy is the durability of antitumor responses observed, with some patients achieving disease control for many years. Nevertheless, not all patients benefit, and efforts should thus now focus on improving the efficacy of immunotherapy through the use of combination approaches and predictive biomarkers of response and resistance. There are multiple potential rational combinations using an immunotherapy backbone, including existing treatments such as radiotherapy, chemotherapy or molecularly targeted agents, as well as other immunotherapeutics. The aim of such antitumor strategies will be to raise the tail on the survival curve by increasing the number of long term survivors, while managing any additive or synergistic toxicities that may arise with immunotherapy combinations. Rational trial designs based on a clear understanding of tumor biology and drug pharmacology remain paramount. This article reviews the biology underpinning immuno-oncology, discusses existing and novel immunotherapeutic combinations currently in development, the challenges of predictive biomarkers of response and resistance and the impact of immuno-oncology on early phase clinical trial design. | Samuel J. Harris Jessica Brown Juanita Lopez Timothy A. Yap | 2016 | Cancer Biology & Medicine2016,13,2: | 6 |
| 4 | ROR2 gene is associated with risk of non-syndromic cleft palate in an Asian population显示文摘背景受体酷氨酸象kinase一样孤儿受体 2 ( ROR2 )基因最近被显示了在动物模型在腭的开发起重要作用并且居住在连接到的 chromosomal 区域非, syndromic 劈开嘴唇与或没有在学习是调查可能的协会在之间的这的 humans.The 目的劈开腭 ROR2 基因和 non-syndromic 我们测试了的这里的口头的 clefts.Methods 在在 297 non-syndromic 的 ROR2 基因的 38 合格单个核苷酸的多型性( SNP ) | Wang Hong Hetmanski, Jacqueline B. Ruczinski, Ingo Liang, Kung Yee Fallin, M. Daniele Redett, Richard J. Raymond, Gerald V. Chou, Yah-Huei Wu Chen, Philip Kuo-Ting Yeow, Vincent Chong, Samuel S. Cheah, Felicia S. H. Jabs, Ethylin Wang Scott, Alan F. Beaty, Terri H. | 2012 | Chinese Medical Journal2012,,3: | 5 |
| 5 | 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society显示文摘 | Craig T. January L. Samuel Wann Joseph S. Alpert Hugh Calkins Joaquin E. Cigarroa Joseph C. Cleveland Jamie B. Conti Patrick T. Ellinor Michael D. Ezekowitz Michael E. Field Katherine T. Murray Ralph L. Sacco William G. Stevenson Patrick J. Tchou Cynthia | 2014 | Circulation2014,,23: | 4 |
| 6 | Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension: A Scientific Statement From the American Heart Association显示文摘 | Michael R. Jaff M. Sean McMurtry Stephen L. Archer Mary Cushman Neil Goldenberg Samuel Z. Goldhaber J. Stephen Jenkins Jeffrey A. Kline Andrew D. Michaels Patricia Thistlethwaite Suresh Vedantham R. James White Brenda K. Zierler | 2011 | Circulation2011,,16: | 3 |
| 7 | A Randomized, Prospective, Double-Blind, Placebo-Controlled Trial of Terlipressin for Type 1 Hepatorenal Syndrome显示文摘 | Arun J. Sanyal Thomas Boyer Guadalupe Garcia–Tsao Frederick Regenstein Lorenzo Rossaro Beate Appenrodt Andres Blei Veit Gülberg Samuel Sigal Peter Teuber | 2008 | Gastroenterology2008,,5: | 3 |
| 8 | Outcomes After Minimally Invasive Esophagectomy: Review of Over 1000 Patients显示文摘 | James D. Luketich Arjun Pennathur Omar Awais Ryan M. Levy Samuel Keeley Manisha Shende Neil A. Christie Benny Weksler Rodney J. Landreneau Ghulam Abbas Matthew J. Schuchert Katie S. Nason | 2012 | Annals of Surgery2012,,1: | 3 |
| 9 | Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005–2009显示文摘 | Anne T.Berg Samuel F.Berkovic Martin J.Brodie JeffreyBuchhalter J. HelenCross WalterVan Emde Boas JeromeEngel JacquelineFrench Tracy A.Glauser Gary W.Mathern Solomon L.Moshé DouglasNordli PerrinePlouin Ingrid E.Scheffer | 2010 | Epilepsia2010,,4: | 3 |
| 10 | 前十字韧带在维持膝关节稳定性上的重要性显示文摘前十字韧带(anterior cruciate ligament,ACL)是膝关节的四条主要韧带之一,其功能是与膝关节内部及周围的其他解剖结构共同维持膝关节的静态和动态平衡。ACL具有复杂的三维结构,传统上将ACL分为两束,前内侧束和后外侧束…,是以韧带在胫骨上的插入方向命名的(图1)。ACL起始于胫骨髁间隆起的前区,延伸至股骨髁间窝后外侧。 | Samuel K. Van de Velde Thomas J. Gill 李国安 | 2007 | 中华骨科杂志2007,27,11: | 3 |
| 11 | Effect of Obesity and Insulin Resistance on Myocardial Substrate Metabolism and Efficiency in Young Women显示文摘 | Linda R. Peterson Pilar Herrero Kenneth B. Schechtman Susan B. Racette Alan D. Waggoner Zulia Kisrieva-Ware Carmen Dence Samuel Klein JoAnn Marsala Timothy Meyer Robert J. Gropler | 2004 | Circulation: Journal of the American Heart Association2004,,18: | 2 |
| 12 | Telbivudine Improves Renal Function in Patients With Chronic Hepatitis B显示文摘 | Edward J. Gane Gilbert Deray Yun-Fan Liaw Seng Gee Lim Ching-Lung Lai Jens Rasenack Yuming Wang George Papatheodoridis Adrian Di Bisceglie Maria Buti Didier Samuel Alkaz Uddin Sophie Bosset Aldo Trylesinski | 2014 | Gastroenterology2014,,1: | 2 |
| 13 | Effects of Random Allocation to Vitamin E Supplementation on the Occurrence of Venous Thromboembolism: Report From the Women’s Health Study显示文摘 | Robert J. Glynn Paul M Ridker Samuel Z. Goldhaber Robert Y.L. Zee Julie E. Buring | 2007 | Circulation2007,,13: | 2 |
| 14 | Combination immunotherapy with soluble tumor necrosis factor receptors plus interleukin 1 receptor antagonist decreases sepsis mortality显示文摘 | Daniel G. Remick Douglas R. Call Samuel J. Ebong David E. Newcomb Pia Nybom Jean A. Nemzek Gerald E. Bolgos | 2001 | Critical Care Medicine2001,,: | 2 |
| 15 | 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society显示文摘 | Craig T. January L. Samuel Wann Joseph S. Alpert Hugh Calkins Joaquin E. Cigarroa Joseph C. Cleveland Jamie B. Conti Patrick T. Ellinor Michael D. Ezekowitz Michael E. Field Katherine T. Murray Ralph L. Sacco William G. Stevenson Patrick J. Tchou Cynthia | 2014 | Circulation2014,,23: | 2 |
| 16 | Paradoxical Increase in Ventricular Torsion and Systolic Torsion Rate in Type I Diabetic Patients Under Tight Glycemic Control显示文摘 | Jina Chung Paul Abraszewski Xin Yu Wei Liu Andrew J. Krainik Marvin Ashford Shelton D. Caruthers Janet B. McGill Samuel A. Wickline | 2006 | Journal of the American College of Cardiology2006,,2: | 2 |
| 17 | BIOGENIC MANGANESE OXIDES: Properties and Mechanisms of Formation显示文摘 | Bradley M. Tebo John R. Bargar Brian G. Clement Gregory J. Dick Karen J. Murray Dorothy Parker Rebecca Verity Samuel M. Webb | 2004 | Annual Review of Earth and Planetary Sciences2004,,: | 2 |
| 18 | P1232 SOFOSBUVIR AND RIBAVIRIN FOR THE TREATMENT OF RECURRENT HEPATITIS C INFECTION AFTER LIVER TRANSPLANTATION: RESULTS OF A PROSPECTIVE, MULTICENTER STUDY显示文摘 | D. Samuel M. Charlton E. Gane R. Brown M. Curry P. Kwo R. Fontana R. Gilroy L. Teperman A.J. Muir J.G. McHutchison W.T. Symonds J. Denning L. McNair S. Arterburn N. Terrault X. Forns M. Manns | 2014 | Journal of Hepatology2014,,1: | 2 |
| 19 | Targeted therapy for gastric cancer: Molecular pathways and ongoing investigations显示文摘 | Wei Yang Alexander Raufi Samuel J. Klempner | 2014 | BBA - Reviews on Cancer2014,,: | 2 |
| 20 | Intravoxel incoherent motion MR imaging for prostate cancer: An evaluation of perfusion fraction and diffusion coefficient derived from different b ‐value combinations显示文摘 | Yuxi Pang Baris Turkbey Marcelino Bernardo Jochen Kruecker Samuel Kadoury Maria J. Merino Bradford J. Wood Peter A. Pinto Peter L. Choyke | 2012 | Magn Reson Med2012,,: | 2 |