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322篇 您的检索式：作者名="Sanders A P"

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	题名	作者	年代	出处	被引量
1	Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘	W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van	1997	Cell1997，，2：	6
2	ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients显示文摘AIM:To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn’s disease(CD).METHODS:In this study,we assessed the differential responses in phagocytosis by measuring the phagocytic activity and the percentage of active phagocytic monocytes and granulocytes in inflammatory bowel disease patients as well as healthy controls.As both autophagy related like 1(ATG16L1)and immunityrelated guanosine triphosphatase gene are autophagy genes associated with CD and more recently nucleo-tide-binding ligomerization domain-containing protein2(NOD2)has been identified as a potent inducer of autophagy we genotyped the patients for these variants and correlated this to the phagocytic reaction.The genotyping was done with restriction fragment length polymorphisms analysis and the phagocytosis was determined with the pHrodo?Escherichia coli Bioparticles Phagocytosis kit for flowcytometry.RESULTS:In this study,we demonstrate that analysis of the monocyte and granulocyte populations of patients with CD and ulcerative colitis showed a comparable phagocytic activity(ratio of mean fluorescence intensity)between the patient groups and the healthy controls.CD patients show a significantly higher phagocytic capacity(ratio mean percentage of phagocytic cells)compared to healthy controls(51.91%±2.85%vs 37.67%±7.06%,P=0.05).The extend of disease was not of influence.However,variants of ATG16L1(WT:2.03±0.19 vs homozygoot variant:4.38±0.37,P<0.009)as well as NOD2(C-ins)(heterozygous variant:42.08±2.94 vs homozygous variant:75.58±4.34(P=0.05)are associated with the phagocytic activity in patients with CD.CONCLUSION:Monocytes of CD patients show enhanced phagocytosis associated with the presence of ATG16L1 and NOD2 variants.This could be part of the pathophysiological mechanism resulting in the disease.	Simone CS Wolfkamp Caroline Verseyden Esther WM Vogels Sander Meisner Kirsten Boonstra Charlotte P Peters Pieter CF Stokkers Anje A te Velde	2014	World Journal of Gastroenterology2014，20，10：	2
3	Elastic and tensile behavior of nanocrystalline copper and palladium显示文摘	Sanders P G Eastman J A Weertman J R	1997	Acta Mater1997，45，10：	2
4	Microparticles: major transport vehicles for distinct microRNAs in circulation 显示文摘	Diehl P Fricke A Sander L	2012	Cardiovasc Res2012，93，4：	1
5	No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘	Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W	2008	The American Journal of Psychiatry2008，，4：	1
6	Polynomial time algo- rithms for multicast network code construction显示文摘	Jaggi S Sanders P Chou P A	2005	IEEE Transactions on Information Theory2005，51，6：	1
7	Modulation of cardiac ryanodine receptors by sorcin显示文摘	Lokuta A J Meyers M B Sander P R	1997	J Biol Chem1997，272，25：	1
8	Correlation of molecular resist- ance mechanisms and phenotypic resistance levels in streptomycin- resistant Mycobacterium tuberculosis 显示文摘	Meier A Sander P Schaper K J	1996	Antimicrob Agents Che- mother1996，40，：	1
9	Effects of insulin and insulin-like growth factors oncultured human hair follicles:IGF-1 at physiologicconcentrations is an important regulator of hair folli-cle growth in vitro显示文摘	PHILPOTT M P SANDERS D A KEALEY T	1994	J Invest1994，102，6：	1
10	Polynomial time algorithms for multicast network code construction显示文摘	JAGGI S SANDERS P CHOU P A	2005	IEEE Trans on Information Theory2005，51，6：	1
11	Polynomial time algo- rithms for multicast network coding construction 显示文摘	JAGGI S SANDERS P CHOU P A	2005	IEEE Trans- actions on Information Theory2005，51，6：	1
12	Elastic and tensile behavior of nanocrystalline copper and palladium显示文摘	Sanders P G Eastman J A Weertman J R		0，，10：	1
13	Modeling and calculation of turbulent lifted diffusion flames显示文摘	LAMERS A P G G	1994	Combustion and Flame1994，96，：	1
14	Focal atrial tachycardia arising from the mitral annulus electrocardiographic and electrophysiologic characterization显示文摘	Kalman JM Sanders P Hussin A	2003	J Am Coll Cardiol2003，41，12：	1
15	Economic merit of crossbred and purebred US dairy cattle 显示文摘	VANRADEN P M SANDERS A H	2003	J Dairy Sci2003，86，：	1
16	Effects of insulin-like growth factors on cultured human hair follicles : IGF-1 at physiological concentrations is an important regulator of hair follicle growth in vitro 显示文摘	Philpott M P Sanders D A Kealey T	1994	J Invest Dermatol1994，102，：	1
17	Operative treatmeent in 120 displaced intra-articular calcaneal fractures:results using a prognostic computed tomography scan classification显示文摘	Sanders R Fortin P DiPasquale A	1993	Clin Orthop Relat Resm1993，2，90：	1
18	Telomerase expression predicts unfavorable outcome in osteosareoma 显示文摘	Sanders R P Drissi R Billups C A	2004	J Clin Oncol2004，22，：	1
19	Anther developmentaldefects in Arabidopsis thaliana male-sterile mutants显示文摘	Sanders P M Bui A Q Weterings K	1999	SexualPlant Reproduction1999，11，：	1
20	Opals 显示文摘	Darmgh P J Gaskin A J Sanders J V	1976	Scientific American1976，234，：	1

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