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| 1 | Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation. | A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi | 2006 | World Journal of Gastroenterology2006，12，33： | 4 |
| 2 | Comparison of HE4, CA125 and ROMA algorithm in women with a pelvic mass: cor- relation with pathological outcome 显示文摘 | Sandri MT Bottari F Franchi D | 2013 | Gynecol Oncol2013，128，2： | 1 |
| 3 | Integrin signaling and lung cancer显示文摘 | Caccavari F Valdembri D Sandri C | 2010 | Cell Adhesion & Migration2010，4，1： | 1 |
| 4 | Comparison of HE4,CA125 and ROMA algorithm in women with a pelvic mass:correlation with pathological outcome显示文摘 | Sandri MT Bottari F Franchi D | 2013 | Gynecologic Oncol2013，128，： | 1 |
| 5 | Enzymatic and immunochemical evaluation of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in testes and epididymal spermatozoa of rats of different ages显示文摘 | Tramer F Micali F Sandri G | 2002 | Int J Androl2002，25，2： | 1 |
| 6 | Comparison ofHE4,CA125 and ROMA algorithm in women with a pel- vic mass:correlation with pathological outcome显示文摘 | Sandri MT Bottari F Franchi D | 2013 | Gyne- col Oncol2013，128，2： | 1 |
| 7 | Assessment of chitosan derivatives as buccal and vaginal penetration enhancers显示文摘 | Sandri G Rossi S Ferrari F | 2004 | Eur J Pharm Sci2004，21，： | 1 |
| 8 | Prophylactic or early selective serfactant combined with nCPAP in very preterminfants 显示文摘 | SANDRI F PLAVKA R ANCORA G | 2010 | Pediatrics2010，125，6： | 1 |
| 9 | Comparison of HEA, CA125 and ROMA algorithm in women with a pelvic mass:cor- relation with pathological outcome显示文摘 | Sandri MT Bottari F Franchi D | 2013 | Gynecnl Oncol2013，128，2： | 1 |
| 10 | Prophylactic nasal continuous positive airways pressure in newborns of 28-31 weeks gestation:Multicentre randomised controlled clinical trial显示文摘 | Sandri F Ancora G Lanzoni A | 2004 | Arch Dis Child Fetal Neonatal Ed2004，89，5： | 1 |
| 11 | Term delivery rate after hysteroscopic metroplasty in patients with recurrent spontaneous abortion and T-shaped, arcuate and septate uterus 显示文摘 | Giacomucci El Bellavia E Sandri F | 2011 | Gynecol Obstet Invest2011，71，3： | 1 |
| 12 | Prophylactic nasal continuous positive airways pressure in newborns of 28 -31 weeks gestation: multicentre randomize controlled clinical trial 显示文摘 | Sandri F Ancora G Lanzoni A | 2004 | Arch Dis Child Fetal Neonatal Ed2004，，5： | 1 |
| 13 | Comparison o{ HE4, CAI25 and ROMA algorithm in women with a pelvic mass: correlation with pathological outcome显示文摘 | Sandri MT Bottari F Franchi D | 2013 | Gynecologic oncology2013，128，2： | 1 |
| 14 | Prophylactic nasal Continuous positive airway pressure in newborns of 28-31 weeks gestation:Multicenter randomized controlled clinical trial显示文摘 | Sandri F Ancora G Lanzoni A | 2004 | Arch Dis Child Fetal Neonatal2004，89，： | 1 |
| 15 | Comparison of HF4, CA125 and ROMA algorithm in women with a pelvic mass : Cor- relation with pathological outcome 显示文摘 | Sandri M T Bottari F Franchi D | 2013 | Gynecologic Oncology2013，128，2： | 1 |
| 16 | Term delivery rate after hysteroscopic metroplasty in patients with recurrent spontaneous abortion and T-shaped, arcuate and septate uterus显示文摘 | Giaeomueei E Bellavia E Sandri F | 2011 | Gynecol Obstet Invest2011，71，3： | 1 |
| 17 | Sonography of fetal agenesis of cor- pus callosum : a survry of 35 cases 显示文摘 | Pilu G Sandri F Perolo A | 1993 | Ultrasound Obstet Gynecol1993，3，5： | 1 |
| 18 | Long-term results after treatment for recurrent thymoma: a multicenter analysis 显示文摘 | Sandri A Cusumano G Lococo F | 2014 | J Thorac Oneol2014，9，12： | 1 |
| 19 | Enzymatic and immunochemical evaluation of phospholipid hydroperoxide glutathione pertxidase(PHGPx)in teates and epididymal spermatozoa of rats of different ages显示文摘 | Tramer F Micali F Sandri G | | 0，，： | 1 |
| 20 | Sonography of fetal agenesis of the corpus callosum: a survey of 35 cases 显示文摘 | Pilu G Sandri F Perolo A | 1993 | Ultrasound Obstet Gynecol1993，3，： | 1 |
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