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| 1 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020,26,32: | 3 |
| 2 | Catalytic reforming of methane with CO2 over metal foam based monolithic catalysts显示文摘 | SANG L X SUN B TAN H Y | 2012 | International Journal ofHydrogen Energy2012,37,13: | 1 |
| 3 | Lithium insertion into the raw multi-walled carbon nanotubes pre-doped with lithium--an electrochemical impedance study 显示文摘 | YANG Z H SANG S B HUANG K L | 2004 | Diamond and Related Ma- terials2004,13,: | 1 |
| 4 | Synergy Effect of Naphthenic Acid Corrosion and Sulfur Corrosion in Crude Oil Distillation Unit显示文摘 | HUANG B S YIN W F SANG D H | 2012 | Applied Surface Science2012,259,: | 1 |
| 5 | Speciation of chromium in water samples with cloud point extraction separation and preconcentration and determination by graphite furnace atomic absorption spectrometry显示文摘 | Liang P Sang H B | 2008 | Journal of Hazardous Materials2008,154,: | 1 |
| 6 | The removal of nitrogen using an autotrophic hybrid hollow-fiber membrane biofilm reactor 显示文摘 | Shin J H Sang B I Chung Y C | 2005 | Desalination2005,183,123: | 1 |
| 7 | Virtual target differential game midcourse guidance law for hypersonic cruise missile based on neural network显示文摘 | Sang B H Jiang C S | 2008 | Transactions of Nanjing University of Aeronautics & Astronautic2008,25,2: | 1 |
| 8 | Determination of trace lead in biological and water samples with dispersive liquid-liquid microextraction preconcentration 显示文摘 | Liang P Sang H B | 2008 | Analytical Bio- chemistry2008,380,: | 1 |
| 9 | Experimental assessment of vibration serviceability of stair systems 显示文摘 | SANG B K YOUNG H ANDREW S | 2008 | Journal of Constructional Steel Research2008,64,2: | 1 |
| 10 | Circulation of solid andgas bypassing in an internally circulating fluidized bed with adraft tube 显示文摘 | Song B H Young T K Sang D K | 1997 | Chemical Engineering ] ournal1997,68,: | 1 |
| 11 | Cytotoxicity of urushiols isolated from sap of korean lacquer tree (Rhus vernicifera Stokes) 显示文摘 | DONG H H SANG B H CHANG W L | 1999 | Archives of Pharmacal Research1999,22,6: | 1 |
| 12 | The dynamic, static and meta-dynamic recrystallization of a Nb-microallyed steel 显示文摘 | Sang H C Kang K B Jonas J J | 2001 | ISIJ Lnt2001,41,1: | 1 |
| 13 | The removal of nitrogen using an autotrophic hybrid hollow-fiber membrane biofilm reactor显示文摘 | Sang B I Chung Y C | 2005 | Desalination2005,183,123: | 1 |
| 14 | Role of hardening solutes on the microstructure and strength of AA6111 automotive alloy 显示文摘 | Gupta A K Bookbinder J B Sang H S | 2000 | Materials Science Forum2000,,: | 1 |
| 15 | Determination of trace lead in biological and water samples with dispersive liquid-liquid microextraction preconcentration显示文摘 | Liang P Sang H B | 2008 | Anal Biochem2008,380,1: | 1 |
| 16 | Genetic Control of a Transition from black to straw-white seed hull in rice domestication显示文摘 | Zhu B F Si L Wang Z Zhou Y Zhu J Shangguan Y Lu D Fan D Li C Lin H Qian Q Sang T Zhou B Minobe Y Hun B | | 0,,03: | 1 |
| 17 | Material property identification of composite plantes using neural network and evolution algorithm显示文摘 | Sang B J Park J W Yong H | 2002 | AIAA Journal2002,40,9: | 1 |
| 18 | Investigation of the Carbon Coating on Quartz Ampoules for Cd Zn Te Crystal Growth显示文摘 | Min J H Sang W B Qian Y B | 2005 | Journal of Synthetic Crystals2005,11,2: | 1 |
| 19 | Formation of silver nanoparticles by laser ablation of a silver target in NaCl solution显示文摘 | Chang H B Sang H N Seung M P | 2002 | Applied Surface Science2002,,: | 1 |
| 20 | Microstructures and mechanical properties of A12 03 -C refractories with silicon additive using different carbon sources 显示文摘 | Fan H B Li Y W Sang S B | 2011 | Materials Science and engineering A2011,528,2011: | 1 |