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| 1 | Acid suppressive drugs and gastric cancer: A meta-analysis of observational studies显示文摘AIM: To evaluate the association between acid suppressive drug use and the development of gastric cancer. METHODS: A systematic search of relevant studies that were published through June 2012 was conducted using the MEDLINE (PubMed), EMBASE, and Cochrane Library databases. The search included observational studies on the use of histamine 2-receptor antagonists (H 2 RAs) or proton pump inhibitors and the associated risk of gastric cancer, which was measured using the adjusted odds ratio (OR) or the relative risk and 95%CI. An independent extraction was performed by two of the authors, and a consensus was reached. RESULTS: Of 4595 screened articles, 11 observational studies (n = 94558) with 5980 gastric cancer patients were included in the final analyses. When all the studies were pooled, acid suppressive drug use was associated with an increased risk of gastric cancer risk (adjusted OR = 1.42; 95%CI: 1.29-1.56, I2 = 48.9%, P = 0.034). The overall risk of gastric cancer increased among H 2 RA users (adjusted OR = 1.40; 95%CI: 1.24-1.59, I2 = 59.5%, P = 0.008) and PPI users (adjusted OR = 1.39; 95%CI: 1.19-1.64, I2 = 0.0%, P = 0.377). CONCLUSION: Acid suppressive drugs are associated with an increased risk of gastric cancer. Further studies are needed to test the effect of acid suppressive drugs on gastric cancer. | Jeong Soo Ahn Chun-Sick Eom Christie Y Jeon Sang Min Park | 2013 | World Journal of Gastroenterology2013，19，16： | 12 |
| 2 | Intergranule interaction in magnetic granular films显示文摘 | DU Y W SANG H XU Q Y | 2000 | Materi Sci & Engin2000，286，1： | 1 |
| 3 | Pyridine-derived gamma- secretase modulators 显示文摘 | WAN Z HALL A SANG Y | 2011 | Bioorg Med Chem Lett2011，21，16： | 1 |
| 4 | Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition 显示文摘 | YING M WANG S SANG Y | 2011 | Oncogene2011，30，31： | 1 |
| 5 | Murine models of systemic lupus erythematosus 显示文摘 | Perry D Sang A Yin Y | 2011 | J Biomed Biotechnol2011，，27： | 1 |
| 6 | Porcine host defense peptides: Expan- ding repertoire and functions 显示文摘 | Sang Y Blecha F | 2009 | Dev Comp Immunol2009，33，： | 1 |
| 7 | Investigation of curing kinetics of various cycloaliphatic epoxy resins using dynamic thermal analysis显示文摘 | Myong J Y Sang H K Seong D | 2010 | European Polymer Journal2010，46，5： | 1 |
| 8 | Effect of rice bran dietary fiber on flour rheolo-gy and quality of wet noodles 显示文摘 | Young S K Tea Y H SANG H L | 1997 | KoreanJournal of Food Science and Technology1997，29，1： | 1 |
| 9 | Isolation and identification ofcytotoxic compounds from bay leaf(Laurus nobilis)显示文摘 | Fang F Sang S Chen K Y | 2005 | FoodChem2005，93，3： | 1 |
| 10 | Interracial effect on effective dielectric response of spherical granular composites显示文摘 | Sang Z F Li Z Y | 2004 | Phys Lett A2004，331，： | 1 |
| 11 | Effect of vacuum thermal cyclic exposures on unidirectional carbon fiber/epoxy composites for low earth orbit space applications 显示文摘 | Sang Y P Heung S C Won J C | 2012 | Composites : Part B2012，43，2： | 1 |
| 12 | Properties of defect modes in one-dimensional photonic crystals containing a graded defect layer 显示文摘 | Z E Sang Z Y Li | 2007 | Opt Commun2007，273，1： | 1 |
| 13 | Suppression of inducible nitric oxide synthase and cyclooxygenase-2 in downregulating nuclear factor-kappa B pathway by Garcinol显示文摘 | Liao C H Sang S Liang Y C | 2004 | Molecular Carcinogenesis2004，41，3： | 1 |
| 14 | Korean ubiquitous-eco-city: a smart-sustainable urban form or a branding hoax显示文摘 | Tan Y Sang H L | 2014 | Technological Forecasting and Social Change2014，89，11： | 1 |
| 15 | Catalytic reforming of methane with CO2 over metal foam based monolithic catalysts显示文摘 | SANG L X SUN B TAN H Y | 2012 | International Journal ofHydrogen Energy2012，37，13： | 1 |
| 16 | HMMR maintains thesternness and tumorigenicity of glioblastoma stem-like cells显示文摘 | Tilghman J Wu H Sang Y | 2014 | Cancer Res2014，74，11： | 1 |
| 17 | Municipal landfill leachate induces cytogenetie damage in root tips of Hordettm vulgare显示文摘 | Sang N Li G K Xin X Y | 2006 | Ecotoxicology and environ- mental safety2006，63，3： | 1 |
| 18 | Structure and Functional Properties of Sorghum Starches Differing in Amylose Content 显示文摘 | Sang Y J Bean S Seib P A | 2008 | Agrie Food Chem2008，56，16： | 1 |
| 19 | Experiments on non-resonant sloshing in a rectangular tank with large ampli- tude lateral oscillation显示文摘 | MOO JI Y SUP SHIN Y SANG PARK J | 2012 | Ocean Engineering2012，50，： | 1 |
| 20 | Cross-species analysis of the mammalian beta-defensin gene family:presence of syntenic gene clusters and preferential expression in the male reproductive tract显示文摘 | Patil AA Ca Y Sang Y Blecha F Zhang G | | 0，，01： | 1 |
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