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| 1 | Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7,Species Differences, and Regulation by Paclitaxel显示文摘Voltage-gated sodium channels(Navs) play an important role in human pain sensation. However, the expression and role of Nav subtypes in native human sensory neurons are unclear. To address this issue, we obtained human dorsal root ganglion(hDRG) tissues from healthy donors. PCR analysis of seven DRG-expressed Nav subtypes revealed that the hDRG has higher expression of Nav1.7(~50% of total Nav expression) and lower expression of Nav1.8(~12%), whereas the mouse DRG has higher expression of Nav1.8(~45%) and lower expression of Nav1.7(~18%). To mimic Nav regulation in chronic pain, we treated hDRG neurons in primary cultures with paclitaxel(0.1-1 μmol/L) for 24 h. Paclitaxel increased the Nav 1.7 but not Nav1.8 expression and also increased the transient Na^+ currents and action potential firing frequency in small-diameter(<50 μm) hDRG neurons. Thus, the hDRG provides a translational model in which to study'human pain in a dish' and test new pain therapeutics. | Wonseok Chang Temugin Berta Yong Ho Kim Sanghoon Lee Seok-Yong Lee Ru-Rong Ji | 2018 | Neuroscience Bulletin2018,34,1: | 12 |
| 2 | Antiviral treatment for hepatitis B virus recurrence following liver transplantation显示文摘 | Sanghoon Lee Choon Hyuck D. Kwon Hyung Hwan Moon Tae‐Seok Kim Youngnam Roh Sanghyun Song Milljae Shin Jong Man Kim Jae Berm Park Sung Joo Kim Jae‐Won Joh Suk‐Koo Lee | 2013 | Clin Transplant2013,,5: | 3 |
| 3 | CONGESTION OF RIGHT LIVER GRAFT IN LIVING DONOR LIVER TRANSPLANTATION显示文摘 | SungGyu Lee KwangMin Park Shin Hwang YoungJoo Lee DongNak Choi KiHoon Kim KyungSuck Koh SangHoon Han KyuTaek Choi KyuSam Hwang Masatoshi Makuuchi Yasuhiko Sugawara PyungChul Min | 2001 | Transplantation2001,,6: | 2 |
| 4 | CONGESTION OF RIGHT LIVER GRAFT IN LIVING DONOR LIVER TRANSPLANTATION显示文摘 | SungGyu Lee KwangMin Park Shin Hwang YoungJoo Lee DongNak Choi KiHoon Kim KyungSuck Koh SangHoon Han KyuTaek Choi KyuSam Hwang Masatoshi Makuuchi Yasuhiko Sugawara PyungChul Min | 2001 | Transplantation2001,,6: | 1 |
| 5 | Post-weld heat treatment cracking susceptibility of T23 weld metals for fossil fuel applications显示文摘 | Kiduck Park Sanghoon Kim Jungchel Chang Changhee Lee | 2011 | Materials and Design2011,,: | 1 |
| 6 | MIMO beamforming forQoS enhancement via analog,digital and hybrid relaying显示文摘 | PARK Jongrok LEE Sanghoon | 2010 | IEEE Transactions on Broadcasting2010,56,4: | 1 |
| 7 | Foveated video quality assessment显示文摘 | Lee Sanghoon Pattichis M S Bovik A C | 2002 | IEEE Transactions on Multimedia2002,4,1: | 1 |
| 8 | Prevalence and prognosis of acute pancreatitis in critically ill patients with COVID-19显示文摘Background:Coronavirus disease 2019(COVID-19)is a global pandemic issue.In addition to the well-known respiratory and fever symptoms,gastrointestinal symptoms have also been reported.This study aimed to evaluate the prevalence and prognosis of patients with COVID-19 infection complicated with acute pancreatitis in intensive care unit(ICU).Methods:This was a retrospective observational cohort study,and patients aged 18 years or older,ad-mitted into the ICU in a single tertiary center from January 1,2020,to April 30,2022 were enrolled.Patients were identified by electronic medical records and reviewed manually.The primary outcome was the prevalence of acute pancreatitis among ICU patients with COVID-19.The secondary outcomes were the length of hospital stay,need for mechanical ventilation(MV),need for continuous renal replacement therapy(CRRT),and in-hospital mortality.Results:A total of 4133 patients,admitted into the ICU,were screened.Among these patients,389 were infected by COVID-19,and 86 were diagnosed with acute pancreatitis.COVID-19 positive patients were more likely to present with acute pancreatitis than COVID-19 negative patients(odds ratio=5.42,95%confidence interval:2.35-6.58,P<0.01).However,the length of hospital stay,need for MV,need for CRRT,and in-hospital mortality were not significantly different between acute pancreatitis patients with and without COVID-19 infection.Conclusions:Severe COVID-19 infections may cause acute pancreas damage in critically ill patients.How-ever,the prognosis may not differ between acute pancreatitis patients with and without COVID-19 infec-tion. | Dongju Kang SuHo Park Changkyo Oh YuJin Kim JinBae Kim SangHoon Park Myung Seok Lee JaeKeun Park | 2023 | Hepatobiliary & Pancreatic Diseases International2023,22,4: | 1 |
| 9 | Geochemistry and partitioning of trace metals in paddy soils affected by metal mine tailings in Korea显示文摘 | Sanghoon Lee | | 0,,11: | 1 |
| 10 | Magnetotransport properties of GaMnAs based trilayer structures withdifferent thicknesses of InGaAs spacer layer显示文摘 | Hakjoon Lee Sunjae Chung Sanghoon Lee | 2009 | J Appl Phys2009,105,07: | 1 |
| 11 | Magnetotransport properties of ferromagnetic semiconductor GaMnAs-basedsuperlattices显示文摘 | Sanghoon Lee Sunjae Chung Sangyeop Lee | 2012 | Curr Appl Phys2012,12,: | 1 |
| 12 | Geochemistry and partitioning of trace met- als in paddy soils affected by metal mine tailings in Korea 显示文摘 | Sanghoon Lee | 2006 | Geoderma2006,135,10: | 1 |
| 13 | Experimental study on spray break-up and atomization processes from GDI injector using high injection pressure up to 30MPa显示文摘 | Sanghoon Lee Sungwook Park | 2014 | International Journal of Heat and Fluid Flow2014,45,: | 1 |
| 14 | Geochemistry and partitioning of trace metals in paddy soils affected by metal mine tailings in Korea显示文摘 | Sanghoon Lee | 2006 | Geoderm2006,135,: | 1 |
| 15 | Economies of density versus natural advantage:crop choice on the back forty显示文摘 | Thomas J Holmes Sanghoon Lee | 2012 | The Review of Economics and Statistics2012,94,1: | 1 |
| 16 | Heavy metals in the bed and suspended sediments of Anyang River,Korea:Implications for water quality显示文摘 | Sanghoon Lee Ji-Won Moon Hi-Soo Moon | 2003 | Enviromental GeochemistryandHealth2003,25,: | 1 |
| 17 | Screening of Anaplastic Lymphoma Kinase Rearrangement by Immunohistochemistry in Non-small Cell Lung Cancer: Correlation with Fluorescence In Situ Hybridization显示文摘 | Jin Ho Paik Gheeyoung Choe Hyojin Kim Ji-Young Choe Hyun Ju Lee Choon-Taek Lee Jong Seok Lee Sanghoon Jheon Jin-Haeng Chung | 2011 | Journal of Thoracic Oncology2011,,3: | 1 |
| 18 | The role of mechanical stratigraphy in the lateral variations of thrust development along the central Alberta Foothills, Canada显示文摘Fold-thrust belts generally exhibit significant variations in structural styles such as differences in thrust geometries and frequencies in imbrication. A natural laboratory of this pattern is preserved in the central Alberta Foothills of the Canadian Rockies, where differences in thrust geometries are represented by the existence vs. non-existence of triangle zones. To seek the factors that make this difference in these regions in terms of structural geometry, stratigraphic thickness variations and mechanical stratigraphy of the sedimentary layers, structural interpretation is conducted based on admissible cross-sections and well log interpretations. In northern region, a backthrust is detached from an incompetent layer(viz.Nomad Unit of the Wapiabi Formation), which gets thinner from the Foothills to the Plains, indicating that it is developed where the shale layers are pinched out where triangle zone is developed. Backthrust is also developed in the southern region, where mechanical strengths of strata(viz. Bearpaw Formation)increase toward the foreland. In the central region, however, only forethrusts are developed along the weak continuous decollement layers(viz. Turner Valley and Brazeau formations), forming an imbricate fan without development of the triangle zone. Incompetent layers such as the top Wapiabi(Nomad),Brazeau(Bearpaw), Coalspur and Paskapoo formations are also pinched out laterally, forming fault glide horizons in different stratigraphic levels in each region. These results indicate that, along the transport direction, triangle zone is developed in relation to the stratigraphic pinch out of the Nomad Unit in the northern region, and is formed associated with the variations in strengths of the layers constituting the Bearpaw Formation in the southern region. It is notable that all the glide horizons are developed along incompetent layers. However, triangle zones are not developed in the areas of continuous stratigraphy of the Nomad Unit, which does not serve as a glide horizon in the central region. This suggests that factors such as stratigraphic thickness changes of incompetent layers and mechanical stratigraphy of the sedimentary layers play an important role in the development of lateral variations in thrust system evolution in terms of triangle zone vs. imbricate fan in the central Alberta Foothills. | Hyunjung Lee Yirang Jang Sanghoon Kwon Myong-Ho Park Gautam Mitra | 2018 | Geoscience Frontiers2018,9,5: | 1 |
| 19 | Deposi- tion behavior of bulk amorphous NiTiZrSiSn according to the kinetic and thermal energy levels in the kinetic sprayingprocess 显示文摘 | Sanghoon Yoon Hyung Jun Kim Changhee Lee | 2006 | Surface and Coatings Technology2006,200,2021: | 1 |
| 20 | Time of hepatocellular carcinoma recurrence after liver resection and alpha‐fetoprotein Are important prognostic factors for salvage liver transplantation显示文摘 | Sanghoon Lee Choon Hyuck David Kwon Jong Man Kim Jae‐Won Joh Seung Woon Paik Bong‐Wan Kim Hee‐Jung Wang Kwang‐Woong Lee Kyung‐Suk Suh Suk‐Koo Lee | 2014 | Liver Transpl2014,,9: | 1 |