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| 1 | Non-convex hybrid total variation for image denoising显示文摘 | Seungmi Oh Hyenkyun Woo Sangwoon Yun Myungjoo Kang | 2013 | Journal of Visual Communication and Image Representation2013，，3： | 1 |
| 2 | A coordinate gradient descent method for nonsmooth separable minimization显示文摘 | Paul Tseng Sangwoon Yun | 2009 | Mathematical Programming (-)2009，，1： | 1 |
| 3 | A coordinate gradient descent meth- od for nonsmooth separable minimization 显示文摘 | Tseng Paul Yun Sangwoon | 2009 | Mathematical Pro- gramming2009，117，1： | 1 |
| 4 | Metal Ion Induced FRET OFF-ON in Tren/Dansyl-Appended Rhodamine 显示文摘 | Min Hee Lee Hyun Jung Kim Sangwoon Yoon | 2008 | Org Lett2008，10，2： | 1 |
| 5 | Linearized proximal alternating minimization algorithm for motion deblurring by nonlocal regularization显示文摘 | Yun Sangwoon Woo Hyenkyun | 2011 | Pattern Recognition2011，44，6： | 1 |
| 6 | Review: Regulation of SIRT1 in cellular functions:Role of polyphenols 显示文摘 | Sangwoon Chung Hongwei Yao Samuel Caito | 2010 | Archives of Biochemistry and Biophysics2010，501，： | 1 |
| 7 | A new multiplicative denoising variational model based on mth Root transformation 显示文摘 | Sangwoon Y Hyenkyun W | 2012 | Image Processing2012，21，5： | 1 |
| 8 | Alternating minimization algorithm for speckle reduction with a shifting technique显示文摘 | Hyenkyun W Sangwoon Y | 2012 | Image Processing2012，21，4： | 1 |
| 9 | SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice显示文摘 | Yao Hongwei Chung Sangwoon Hwang Jae-woong Rajendrasozhan Saravanan Sundar Isaac K Dean David A McBurney Michael W Guarente Leonard Gu Wei R?nty Mikko Kinnula Vuokko L Rahman Irfan | 2012 | EN2012，，6： | 1 |
| 10 | The transcription factor PU.1 promotes alternative macrophage polarization and asthmatic airway inflammation显示文摘The transcription factor PU.1 is involved in regulation of macrophage differentiation and maturation.However,the role of PU.1 in alternatively activated macrophage(AAM)and asthmatic inflammation has yet been investigated.Here we report that PU.1 serves as a critical regulator of AAM polarization and promotes the pathological progress of asthmatic airway inflammation.In response to the challenge of DRA(dust mite,ragweed,and Aspergillus)allergens,conditional PU.1-deficient(PU/ER(T)^(+/-))mice displayed attenuated allergic airway inflammation,including decreased alveolar eosinophil infiltration and reduced production of IgE,which were associated with decreased mucous glands and goblet cell hyperplasia.The reduced asthmatic inflammation in PU/ER(T)^(+/-) mice was restored by adoptive transfer of IL-4-induced wild-type(WT)macrophages.Moreover,after treating PU/ER(T)^(+/-) mice with tamoxifen to rescue PU.1 function,the allergic asthmatic inflammation was significantly restored.In vitro studies demonstrate that treatment of PU.1-deficient macrophages with IL-4 attenuated the expression of chitinase 3-like 3(Ym-1)and resistin-like molecule alpha 1(Fizz-1),two specific markers of AAM polarization.In addition,PU.1 expression in macrophages was inducible in response to IL-4 challenge,whichwas associated with phosphorylation of signal transducer and activator of transcription 6(STAT6).Furthermore,DRAchallenge in sensitized mice almost abrogated gene expression of Ym-1 and Fizz-1 in lung tissues of PU/ER(T)^(+/-) mice compared with WT mice.These data,all together,indicate that PU.1 plays a critical role in AAM polarization and asthmatic inflammation. | Feng Qian Jing Deng Yong Gyu Lee Jimmy Zhu Manjula Karpurapu Sangwoon Chung Jun-Nian Zheng Lei Xiao Gye Young Park John W.Christman | 2015 | Journal of Molecular Cell Biology2015，7，6： | 1 |
| 11 | Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy显示文摘BACKGROUND A decline in serum carbohydrate antigen 19-9(CA19-9)levels during systemic chemotherapy is considered as a prognostic marker for patients with advanced pancreatic cancer.Neutrophil-to-lymphocyte ratio(NLR)has been extensively studied as a simple and useful indicator of prognosis in various cancers including pancreatic cancer.AIM To assess the prognostic significance of NLR and CA19-9 in patients with advanced pancreatic adenocarcinoma received first-line chemotherapy according to CA19-9 positivity.METHODS We retrospectively analyzed patients diagnosed with advanced pancreatic cancer who received first-line chemotherapy between January 2010 and July 2017 at the Catholic University of Seoul St.Mary’s Hospital.Patients were divided according to CA19-9 positivity(CA19-9-positive vs-negative groups)and pre-and posttreatment NLR levels.To determine cut-off value of NLR and CA19-9 reduction,time-dependent receiver operating characteristic curve was applied.We evaluated overall survival(OS)and progression-free survival(PFS)for each group using Kaplan-Meier method,and we performed multivariate analyses on the entire cohort.RESULTS We included 271 patients in this study.Cut-off value of NLR and CA19-9 reduction was determined as 2.62 and 18%.Multivariate analysis showed that post-treatment NLR<2.62 and reduction of≥18%of baseline CA19-9 were significantly associated with OS and PFS.Post-treatment NLR≥2.62 showed hazard ratio(HR)of 2.47[95%confidence interval(CI):1.84-3.32,P<0.001]and CA19-9 decline(≥18%)showed HR of 0.51(95%CI:0.39-0.67,P<0.001)for OS.When CA19-9-positive patients were divided into groups according to CA19-9 response(responder vs non-responder)and post-treatment NLR(<2.62 vs≥2.62),CA19-9 responder and post-treatment NLR<2.62 group showed better survival than CA19-9 non-responder and post-treatment NLR≥2.62 group(OS 11.0 mo vs 3.9 mo,P<0.001;PFS 6.3 mo vs 2.0 mo,P<0.001).The combination of CA19-9 decline and post-treatment NLR showed a significant correlation with clinical response in CA 19-9 positive group.Within the CA19-9-negative group,the posttreatment NLR<2.62 group showed better survival than the post-treatment NLR≥2.62 group(OS 12.7 mo vs 7.7 mo,P<0.001;PFS 6.7 mo vs 2.1 mo,P<0.001),and post-treatment NLR showed correlation with clinical response.CONCLUSION In advanced pancreatic cancer patients positive for CA19-9 and treated with systemic chemotherapy,the combination of post-treatment NLR<2.62 and 18%decline of CA19-9 at the first response evaluation is a good prognostic marker.Post-treatment NLR<2.62 alone could be used as a prognostic marker and an adjunctive tool for response evaluation in CA19-9-negative patients. | Kabsoo Shin Eun-Kyo Jung Se Jun Park Sangwoon Jeong In-Ho Kim Myung-ah Lee | 2021 | World Journal of Gastrointestinal Oncology2021，13，8： | 1 |
| 12 | An accelerated proximal gradient algorithm for image restoration显示文摘 | Zuowei Shen Kim Chuan Toh Sangwoon Yun | 2009 | Preprint2009，，： | 1 |
| 13 | Regulation of SIRT1 in cellular functions: Role of polyphenols显示文摘 | Sangwoon Chung Hongwei Yao Samuel Caito Jae-woong Hwang Gnanapragasam Arunachalam Irfan Rahman | 2010 | Archives of Biochemistry and Biophysics2010，，1： | 1 |
| 14 | Regulation of SIRT1 in cellular functions: Role of polyphenols显示文摘 | Sangwoon Chung Hongwei Yao Samuel Caito Jae-woong Hwang Gnanapragasam Arunachalam Irfan Rahman | 2010 | Archives of Biochemistry and Biophysics2010，，1： | 1 |
| 15 | A coordinate gradient descent method for nonsmooth separable minimization显示文摘 | Paul Tseng Sangwoon Yun | 2009 | Mathematical Programming (-)2009，，1： | 1 |
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