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| 1 | Evaluation Of a high-velocity flame-spraying technique for hydroxyl apatite显示文摘 | Keiko Ishikawa Satoshi Ojima | 1992 | Biomaterials1992，13，7： | 1 |
| 2 | Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis显示文摘AIM To clarify the histological changes associated with liver atrophy after percutaneous transhepatic portalembolization(PTPE) in pigs and humans. METHODS As a preliminary study, we performed pathological examinations of liver specimens from five pigs that had undergone PTPE in a time-dependent model of liver atrophy. In specimens from embolized lobes(EMB) and nonembolized lobes(controls), we measured the portal vein to central vein distance(PV-CV), the area and number of hepatocytes per lobule, and apoptotic activity using the terminal deoxynucleotidyl transferase dU TP nickend labeling assay. Immunohistochemical reactivities were evaluated for light chain 3(LC3) and lysosomal-associated membrane protein 2(LAMP2) as autophagy markers and for glutamine synthetase and cytochrome P450 2 E1(CYP2 E1) as metabolic zonation markers. Samples from ten human livers taken 20-36 d after PTPE were similarly examined. RESULTS PV-CVs and lobule areas did not differ between EMB and controls at day 0, but were lower in EMB than in controls at weeks 2, 4, and 6(P ≤ 0.001). Hepatocyte numbers were not significantly reduced in EMB at day 0 and week 2 but were reduced at weeks 4 and 6(P ≤ 0.05). Apoptotic activity was higher in EMB than in controls at day 0 and week 4. LC3 and LAMP2 staining peaked in EMB at week 2, with no significant difference between EMB and controls at weeks 4 and 6. Glutamine synthetase and CYP2 E1 zonation in EMB at weeks 2, 4, and 6 were narrower than those in controls. Human results were consistent with those of porcine specimens. CONCLUSION The mechanism of liver atrophy after PTPE has two histological phases: Hepatocellular atrophy is likely caused by autophagy in the first 2 wk and apoptosis thereafter. | Yasuhito Iwao Hidenori Ojima Tatsushi Kobayashi Yoji Kishi Satoshi Nara Minoru Esaki Kazuaki Shimada Nobuyoshi Hiraoka Minoru Tanabe Yae Kanai | 2017 | World Journal of Hepatology2017，9，32： | 1 |
| 3 | Evaluation Of a high-velocity flame-spraying technique for hydroxyl apatite显示文摘 | Keiko Ishikawa Satoshi Ojima | 1992 | Biomaterials1992，13，7： | 1 |
| 4 | Therapeutic value of lymph node dissection during hepatectomy in patients with intrahepatic cholangiocellular carcinoma with negative lymph node involvement显示文摘 | Kazuaki Shimada Tsuyoshi Sano Satoshi Nara Minoru Esaki Yoshihiro Sakamoto Tomoo Kosuge Hidenori Ojima | 2009 | Surgery2009，，4： | 1 |
| 5 | Associations between nondipping of nocturnal blood pressure decrease and cardiovascular target organ damage in strictly selected community-dwelling normotensives显示文摘 | Satoshi Hoshide Kazuomi Kario Yoko Hoshide Yuji Umeda Toru Hashimoto Osamu Kunii Toshiyuki Ojima Kazuyuki Shimada | 2003 | American Journal of Hypertension2003，，6： | 1 |
| 6 | Therapeutic value of lymph node dissection during hepatectomy in patients with intrahepatic cholangiocellular carcinoma with negative lymph node involvement显示文摘 | Kazuaki Shimada Tsuyoshi Sano Satoshi Nara Minoru Esaki Yoshihiro Sakamoto Tomoo Kosuge Hidenori Ojima | 2009 | Surgery2009，，4： | 1 |
| 7 | Surgical Management of Infrahilar/Suprapancreatic Cholangiocarcinoma: an Analysis of the Surgical Procedures, Surgical Margins, and Survivals of 77 Patients显示文摘 | Yoshihiro Sakamoto Kazuaki Shimada Satoshi Nara Minoru Esaki Hidenori Ojima Tsuyoshi Sano Junji Yamamoto Tomoo Kosuge | 2010 | Journal of Gastrointestinal Surgery2010，，2： | 1 |
| 8 | Prognostic impact of marginal resection for patients with solitary hepatocellular carcinoma: Evidence from 570 hepatectomies显示文摘 | Satoshi Nara Kazuaki Shimada Yoshihiro Sakamoto Minoru Esaki Yoji Kishi Tomoo Kosuge Hidenori Ojima | 2012 | Surgery2012，，4： | 1 |
| 9 | PARTICLE-BASED TRANSPARENT FUSED VISUALIZATION APPLIED TO MEDICAL VOLUME DATA显示文摘This paper proposes a method to create 3D fusion images,such as volume–volume,volume–surface,and surface–surface fusion.Our method is based on the particle-based rendering,which uses tiny particles as rendering primitives.The method can create natural and comprehensible 3D fusion images simply by merging particles prepared for each element to be fused.Moreover,the method does not require particle sorting along the line of sight to realize right depth feel.We apply our method to realize comprehensible visualization of medical volume data. | KYOKO HASEGAWA SAORI OJIMA YOSHIYUKI SHIMOKUBO SUSUMU NAKATA KOZABURO HACHIMURA SATOSHI TANAKA | 2013 | International Journal of Modeling, Simulation, and Scientific Computing2013，4，S01： | 0 |
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