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3篇 您的检索式:作者名="Senwei Tang"
    题名 作者 年代 出处 被引量
1Su1990 Integrative Identification of EBV-Associated Variations At Genomic, Epigenomic and Transcriptomic Levels in Gastric Cancer显示文摘Qiaoyi Liang Xiaotian Yao Senwei Tang Tung On Yau Junhong Zhao Joseph J.Y. Sung Jun Yu 2013Gastroenterology2013,,5:1
2Direct-to-consumer genetic testing in China and its role in GWAS discovery and replication显示文摘Background:The direct-to-consumer genetic testing(DTC-GT)industry has exploded in recent years,initiated by market pioneers from the United States and quickly followed by companies from Europe and Asia.In addition to their primary objective of providing ancestry and health information to customers,DTC-GT services have emerged as a valuable data resource for large-scale population and genetics studies.Methods:We assessed DTC-GT market leaders in the U.S.and China,user participation in research,and academic reports based on this information.We also investigated DTC-GT end-user value by tracing key updates of companies provided via health risk reports and evaluating their predictive power.We then assessed the replicability of several genome-wide association studies(GWAS)based on a Chinese DTC-GT biobank.Results:As recent entrants to the market,Chinese DTC-GT serv ice providers have published less academic research than their Western counterparts;however,a larger proportion of Chinese users consent to participate in research projects.Dramatic increases in user volume and resultant report updates led to reclassification of some users'polygenic risk levels,but within a reasonable scale and with increased predictive power.Replicability among GWAS using the Chinese DTC-GT biobank varied by studied trait,population background,and sample size.Conclusions:We speculate that the rapid growth in DTC-GT services,particularly in non-Caucasian populations,will yield an important and much-needed resource for biobanking,large-scale genetic studies,clinical trials,and post-clinical applications.Kang Kang Xue Sun Lizhong Wang Xiaotian Yao Senwei Tang Junjie Deng Xiaoli Wu WeGene Research Team Can Yang Gang Chen 2021Quantitative Biology2021,9,2:0
3Rational design, synthesis and prospect of biodegradable magnesium alloy vascular stents显示文摘Biodegradable magnesium(Mg) alloys are expected to be promising materials for cardiovascular stents(CVS), which can avoid the longterm clinical problems of current CVS, such as in-stent restenosis, late stent thrombosis, etc. Mg alloy stents exhibit superior biocompatibility and tunable biodegradability, compared with conventional permanent metallic stents. However, the poor formability and non-uniform corrosion of Mg alloy stents hinder their clinical application of CVS. This review focuses on the development of Mg alloys for CVS in recent years.According to the results of bibliometric analysis, we analyzed different biodegradable Mg alloy systems. Moreover, the structural design strategies for Mg alloy stents that can reduce the stress concentration, as well as the surface modification methods to control the corrosion behavior and biological performance of Mg alloy stents are also highlighted. At last, this review systematically discussed the potential directions and challenges of biodegradable magnesium stents(BMgS) in cardiovascular fields.Senwei Wang Chengao Du Xin Shen Xiong Wu Sihui Ouyang Jun Tan Jia She Aitao Tang Xianhua Chen Fusheng Pan 2023Journal of Magnesium and Alloys2023,11,9:0
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