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| 1 | Impact of main vessel calcification on procedural and clinical outcomes of bifurcation lesion undergoing provisional single-stenting intervention: a multicenter, prospective, observational study显示文摘Background Few data on the combined effects of bifurcation and calcification on coronary artery disease(CAD)patients undergoing percutaneous coronary intervention(PCI)are available.This study evaluated the impact of main vessel(MV)calcification on the procedural and long-term outcomes in patients with CAD who underwent provisional single stent PCI.Methods This is a multicenter,prospective,observational study.Patients with bifurcation lesions were enrolled at 10 PCI centers in China from January 2015 to December 2017.Intravascular ultrasound or optical coherence tomography was performed in all patients to evaluate the MV calcification.Patients were treated with provisional single stent strategy using drug eluting stents and followed-up at 1 month,6 months and 12 months after discharge by telephone contact or outpatient visit.Repeated coronary imaging was performed within one year.We compared the procedural success rates in MV and in side branch(SB),and target lesion failure(TLF),defined as a composite of cardiac death,non-fatal myocardial infarction,definite or possible stent thrombosis and target lesion revascularization between patients with and without MV calcification.Results A total of 185 subjects were enrolled according to the inclusion and exclusion criteria of this study.MV calcification was detected in 119(64.3%,calcification group)and not found in 66(35.7%,non-calcification group)patients.The angiographic success rate of MV was 95.8%in the calcification group and 97.0%in the non-calcification group(P=0.91);the angiographic success rate of SB was 32.8%in the calcification group and 53.0%in the non-calcification group(P<0.05).During the one-year follow-up period,TLF occurred in 14(11.8%)patients in the calcification group and in 13(19.7%)in the non-calcification group{P=0.31).Multivariate regression analysis showed the same result(HR=1.23,95%CI:0.76-1.52,P=0.47).Calcification on group had higher recurrent angina than non-calcification group(13.51%vs.17.65%,P<0.05).Conclusions In patients with coronary bifurcation lesion treated with provisional one stent approach,calcification of MV is associated with lower SB procedural success rate,it could increase recurrence of angina;however,it was not associated with an increased risk of TLF. | Jing BAI Yan YUE Hong-Qi FENG Shu-Xin HAO Liang PENG Ming ZHANG Shaheena Nazneen Li-Feng LIU Zhe TANG Xiao-Lin YU Yu-Tao XIE Fu-Xiang SHAN Ming-Zhi SHEN Jiang-Tao WANG Xue-Hua WAN Yun-Dai CHEN Yu WANG | 2019 | Journal of Geriatric Cardiology2019，16，2： | 3 |
| 2 | 一例罕见的子宫原始神经外胚层瘤病例报道(英文)显示文摘Primitive neuroectodermal tumor (PNET) of uterus is the rare of the rarest among the tumors of female genital tract. We herein reported a 32 years old female operated for lower abdominal lump,which was diagnosed,as PNET later confirmed by immunohistochemistry (IHC). She was lost to follow-up and presented 10 months later with recurrence. She was treated with cyclical combination chemotherapy followed by definitive surgery and is in complete remission at present. | Syed Nisar Ahmad Shiekh Aejaz Aziz Rangreze Imran Manzoor Ahmad Banday Gul Mohammad A.R.Lone Parveen Reshi Nisar Ahmad Wani Shaheena Parveen | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，6： | 2 |
| 3 | Successful opening in-stent chronic total occlusion lesion of coronary artery by excimer laser coronary angioplasty显示文摘In percutaneous coronary intervention (PCI), chronic total occlusion (CTO) coronary artery disease still remains difficult to treat. One of the reasons for the failure is the hard of the CTO lesions that balloon is difficult to pass through or expand. Previous methods to deal with CTO lesions that cannot be passed by balloon, include selecting reinforced catheter (such as 5 in 6 guiding catheter, Guidzilla catheter, or Tornus microcatheter), guidewire extrusion or rotary grinding technology. In recent years, excimer laser coronary angioplasty (ELCA) has been gradually applied to CTO lesions. Using inert halide as the laser medium, ELCA emits a 308 nm high-intensity unidirectional light wave with absorption depth of only 50 μmL, resulting in less thermal effect and less damage to non-target lesions. In this paper, we will describe a successful PCI case of an in-stent CTO lesion using ELCA with long term coronary angiography follow-up. | Jing BAI Hai-Xia WANG Jiang-Tao WANG Jing ZHAO Liang PENG Xue-Dong YANG Zhe TANG Shaheena Nazneen Gao-Kun WANG Yu WANG | 2019 | Journal of Geriatric Cardiology2019，16，6： | 2 |
| 4 | Prevalence of H elicobacter pylori infection and the effect of its eradication on symptoms of functional dyspepsia in K ashmir, I ndia显示文摘 | Jaswinder Singh Sodhi Gul Javid Showkat Ali Zargar Syed Tufail Altaf Shah Bashir Ahmad Khan Ghulam Nabi Yattoo Ghulam Mohamad Gulzar Mushtaq Ahmad Khan Mohd Iqbal Lone Riyaz u Saif Shaheena Parveen Abid Shoukat | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 5 | Reduction of post-prandial hyperglycemia by mul- berry tea in type-2 diabetes patients显示文摘 | Shaheena Banu Nasimudeen R Nanjappa C M | 2015 | Saudi Journal of Biological Sciences2015，22，： | 1 |
| 6 | Reduction of post-prandial hyperglycemia by mulberry tea in type-2 diabetes patients显示文摘 | Shaheena B Nasimudeen R Nanjappa C | 2015 | Saudi J Biol Sci2015，22，1： | 1 |
| 7 | Comparative study of high sensitivity troponin T and heart-type fatty acid-binding protein in STEMI patients显示文摘 | Shaheena Banu Syed Tanveer C.N. Manjunath | 2015 | Saudi Journal of Biological Sciences2015，，1： | 1 |
| 8 | Gly-LysPred: Identification of Lysine Glycation Sites in Protein Using Position Relative Features and Statistical Moments via Chou’s 5 Step Rule显示文摘Glycation is a non-enzymatic post-translational modification which assigns sugar molecule and residues to a peptide.It is a clinically important attribute to numerous age-related,metabolic,and chronic diseases such as diabetes,Alzheimer’s,renal failure,etc.Identification of a non-enzymatic reaction are quite challenging in research.Manual identification in labs is a very costly and timeconsuming process.In this research,we developed an accurate,valid,and a robust model named as Gly-LysPred to differentiate the glycated sites from non-glycated sites.Comprehensive techniques using position relative features are used for feature extraction.An algorithm named as a random forest with some preprocessing techniques and feature engineering techniques was developed to train a computational model.Various types of testing techniques such as self-consistency testing,jackknife testing,and cross-validation testing are used to evaluate the model.The overall model’s accuracy was accomplished through self-consistency,jackknife,and cross-validation testing 100%,99.92%,and 99.88%with MCC 1.00,0.99,and 0.997 respectively.In this regard,a user-friendly webserver is also urbanized to accumulate the whole procedure.These features vectorization methods suggest that they can play a critical role in other web servers which are developed to classify lysine glycation. | Shaheena Khanum Muhammad Adeel Ashraf Asim Karim Bilal Shoaib Muhammad Adnan Khan Rizwan Ali Naqvi Kamran Siddique Mohammed Alswaitti | 2021 | Computers, Materials & Continua2021，，2： | 0 |
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