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| 1 | Novel therapy for non-cirrhotic hyperammonemia due to a spontaneous splenorenal shunt显示文摘Spontaneous splenorenal shunts in the absence of cirrhosis have rarely been reported as a cause hyperammonemia with encephalopathy. Several closure techniques of such lesions have been described. Here we report a case of a patient with no history of liver disease who developed significant confusion. After an extensive workup, he was found to have hyperammonemia and encephalopathy due to formation of a spontaneous splenorenal shunt. There was no evidence of cirrhosis on biopsy or imaging and no portal hypertension when directly measured. The shunt was 18 mm and too large for embolization so the segment of the splenic vein between the portal vein and the shunt was occluded using an Amplatzer plug. Thus, the superior mesenteric flow was directed entirely to the liver. After interventional radiology closure of the shunt using this technique there was complete resolution of symptoms.The case represents the first report of a successful closure of splenorenal shunt via percutaneous embolization of the splenic vein with an amplatzer plug using a common femoral vein approach. | Shari S Rogal Angela Hu Rupal Bi Obaid Shaikh | 2014 | World Journal of Gastroenterology2014，20，25： | 5 |
| 2 | Celecoxib-induced cholestatic liver failure requiring orthotopic liver transplantation显示文摘Selective cyclooxygenase-2 (COX-2) inhibitors are widely used due to their efficacy and good safety profile. However, recent case reports have described varying degrees of liver injuries associated with the use of COX-2 inhibitors. We report the case of a patient who developed acute cholestatic hepatitis progressing to hepatic failure requiring liver transplantation, following a 3-d course of celecoxib for treatment of generalized muscle aches and pains. The clinical presentation, the laboratory data, as well as the liver histopathology were supportive of the putative diagnosis of drug induced liver injury. | Ihab I El Hajj Shahid M Malik Hany R Alwakeel Obaid S Shaikh Eizaburo Sasatomi Hossam M Kandil | 2009 | World Journal of Gastroenterology2009，15，31： | 4 |
| 3 | 不锈钢等离子体性能的激光诱导击穿光谱法研究显示文摘研究了由Nd:YAG激光的一级及二级谐波(SHG)产生的不锈钢等离子体参数的测量方法。根据已知的谱线进行光谱分析,利用Boltzmann法估算出了激发温度,而等离子体的电子密度是从谱线的Stark展宽剖面估算出来的。在常压下研究了等离子体的空间及时间演化过程,结果发现谱线的积分光强及积分宽度随着时间的延迟而降低。除了逆韧致辐射吸收的估算,同时研究了激光辐照度和波长对等离子体参数的影响。 | SHAIKH Nek M KALHORO M S BAIG M A | 2009 | 冶金分析2009，29，7： | 2 |
| 4 | Ipsilateral breast tumor recurrence in early stage breast cancer patients treated with breast conserving surgery and adjuvant radiation therapy: Concordance of biomarkers and tumor location from primary tumor to in-breast tumor recurrence显示文摘BACKGROUND Patients with an in-breast tumor recurrence(IBTR)after breast-conserving therapy have a high risk of distant metastasis and disease-related mortality.Classifying clinical parameters that increase risk for recurrence after IBTR remains a challenge.AIM To describe primary and recurrent tumor characteristics in patients who experience an IBTR and understand the relationship between these characteristics and disease outcomes.METHODS Patients with stage 0-II breast cancer treated with lumpectomy and adjuvant radiation were identified from institutional databases of patients treated from 2003-2017 at our institution.Overall survival(OS),disease-free survival,and local recurrence-free survival(LRFS)were estimated using the Kaplan Meier method.We identified patients who experienced an isolated IBTR.Concordance of hormone receptor status and location of tumor from primary to recurrence was evaluated.The effect of clinical and treatment parameters on disease outcomes was also evaluated.RESULTS We identified 2164 patients who met the eligibility criteria.The median follow-up for all patients was 3.73[interquartile range(IQR)2.27-6.07]years.Five-year OS was 97.7%(95%CI:96.8%-98.6%)with 28 deaths;5-year LRFS was 98.0%(97.2-98.8)with 31 IBTRs.We identified 37 patients with isolated IBTR,19(51.4%)as ductal carcinoma in situ and 18(48.6%)as invasive disease,of whom 83.3%had an in situ component.Median time from initial diagnosis to IBTR was 1.97(IQR:1.03-3.5)years.Radiotherapy information was available for 30 of 37 patients.Median whole-breast dose was 40.5 Gy and 23 patients received a boost to the tumor bed.Twenty-five of thirty-two(78.1%)patients had concordant hormone receptor status,HER-2 receptor status,and estrogen receptor(ER)(P=0.006)and progesterone receptor(PR)(P=0.001)status from primary to IBTR were significantly associated.There were no observed changes in HER-2 status from primary to IBTR.The concordance between quadrant of primary to IBTR was 10/19[(62.2%),P=0.008].Tumor size greater than 1.5 cm(HR=0.44,95%CI:0.22-0.90,P=0.02)and use of endocrine therapy upfront(HR=0.36,95%CI:0.18-0.73,P=0.004)decreased the risk of IBTR.CONCLUSION Among patients with early stage breast cancer who had breast conserving surgery treated with adjuvant RT,ER/PR status and quadrant were highly concordant from primary to IBTR.Tumor size greater than 1.5 cm and use of adjuvant endocrine therapy were significantly associated with decreased risk of IBTR. | Juhi M Purswani Fauzia Shaikh S Peter Wu Jennifer Chun Kim Freya Schnabel Nelly Huppert Carmen A Perez Naamit K Gerber | 2020 | World Journal of Clinical Oncology2020，11，1： | 2 |
| 5 | Thermotropic liq-uid crystalline behavior of cholesterol-linked hydroxyethylcellulose显示文摘 | Shaikh V A E Maldar N N Lonikar S V | 1999 | Journal of Applied Polymer Science1999，72，6： | 1 |
| 6 | Celiac artery aneurysm em- bolization by coil occlusion 显示文摘 | Syed M Shaikh A Neravetla S | 2005 | Ann Vase Surg2005，19，： | 1 |
| 7 | Hepatitis B immune globulin 显示文摘 | Habib S Shaikh OS | 2007 | Drugs Today ( Barc )2007，43，6： | 1 |
| 8 | Binding of trazodone hydrochloride with human serum albumin: A spectroscopic study 显示文摘 | Kandagal P B Seetharamappa J Shaikh S M T | 2007 | J Photochem Photobiol A2007，185，： | 1 |
| 9 | Ultrasound imaging for lumbar punctures and epidural catheterizations:systematic review and meta-analysis显示文摘 | Shaikh F Brzezinski J Alexander S | 2013 | BMJ2013，346，： | 1 |
| 10 | Soybean seed qualityduring storage:a review显示文摘 | SHELAR V R SHAIKH R S NIKAM A S | 2008 | Agric Rev2008，29，2： | 1 |
| 11 | Frequency of hyponatraemia and its influence on liver cirrhosis-related complications 显示文摘 | Shaikh S Mal G Khalid S | 2010 | J Pak Med Assoc2010，60，2： | 1 |
| 12 | Spectroscopic characterization of laser ablation brass plasma显示文摘 | Shaikh N M Hafeez S Kalyar M A | 2008 | J Appl Phys2008，104，10： | 1 |
| 13 | A study of the interaction between bromopyrogallol red and bovine serum albumin by spectroscopic methods显示文摘 | Shaikh S M T Seetharamappa J Ashoka S | 2007 | Dyes and Pigments2007，73，： | 1 |
| 14 | Oleic and doc- osahexaenoic acid differentially phase separate from lipid raft mole- cules: a comparative NMR, DSC, AFM, and detergent extraction study 显示文摘 | SHAIKH S R DUMAUAL A C CASTILLO A | 2004 | Biophysical Journal2004，87，3： | 1 |
| 15 | Genetic variation inexon 17 of INSR is associated with insulin resistance and hy-perandrogenemia among lean Indian women with polycystic ova-ry syndrome显示文摘 | Mukherjee S Shaikh N Khavale S | 2009 | Eur J Endocrinol2009，160，5： | 1 |
| 16 | Facile and low cost chemo- synthesis of nanostruetured PbS with tunable optical properties 显示文摘 | Pawar S B Shaikh J S Devan R S | 2011 | Applied Surface Science2011，258，5： | 1 |
| 17 | Efficacy of trans- dermal nitroglycerine in idiopathic pre - term labour 显示文摘 | SHAIKH S SHAIKH A H AKHTER S | 2012 | J Pak Med Assoc2012，62，1： | 1 |
| 18 | Obesity in pregnancy: a major healthcare issue显示文摘 | Tsoi E Shaikh H Robinson S | 2010 | Postgrad Med J2010，86，1020： | 1 |
| 19 | A study on ethosomes as mode for transdermal delivery of an antidiabetic drug显示文摘 | Bodade S S Shaikh K S Kamble M S | 2013 | Drug Deliv2013，20，1： | 1 |
| 20 | Preparation and characterization of molecularly imprinted polymer for di(2-ethylhexyl) phthalate: Application to sample clean-up prior to gas chromatographic determination显示文摘 | Shaikh H Memon N Khan H Bhanger M I and Nizamani S M | 2012 | Journal of Chromatogrphy A2012，1247，： | 1 |
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