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| 1 | Texture control by {10-12} twinning to improve the formability of Mg alloys: A review显示文摘Texture control of wrought Mg alloys, particularly in rolled Mg alloy sheets, has been an important research topic for the past several decades because it has significant influence on stretch formability at room temperature. For Mg alloys, {10-12} twinning can be easily activated and causes a 86.3° lattice rotation. Thus, pre-twinning deformation is considered as an effective and low-cost method for texture control in wrought Mg and its alloys. Furthermore, it has been verified that texture control via pre-twinning deformation can remarkably improve stretch formability of rolled Mg alloy sheets. In this review, recent researches on texture control via twinning deformation and its influence on stretch formability will be critically reviewed. The main contents include the micro-mechanism and impact factors of control in twin-orientation, plastic processing techniques of pre-inducing twins and the application of pre-induced twins in improvement of stretch formability. Finally, further research directions on this field were proposed. | Bo Song Qingshan Yang Tao Zhou Linjiang Chai Ning Guo Tingting Liu Shengfeng Guo Renlong Xin | 2019 | Journal of Materials Science & Technology2019，35，10： | 8 |
| 2 | Experimental Study on Formation Conditions of Ammoniojarosite and Its Environmental Significance显示文摘在 systemFe_2 (SO_4 ) 的 ammoniojarosite 的形成条件 _3-(NH_4 )_2SO_4-H_2O 在这篇论文被调查。结果证明 ammoniojarositecan 被控制合适的 pH andFe_2 (SO_4 ) 在标准温度和压力下面很快形成 _3 并且(NH_4 )_2SO_4 集中。pH,温度和集中 ofFe_2 (SO_4 )_3 媒介是影响 ammoniojarosite 的形成的关键因素。在标准温度下面, ammoniojarosite 的降水能在在 2.6 -3.1, 之间的 pH 在 24 个小时以内被看见, ammoniojarosite 的大数量在 48 个小时以内被形成。在大约 90 deg C,形成 ammoniojarosite 的 pHvalue 范围延长到 1.2 - 3.1,并且在这个范围以内, pH 的上升对 ammoniojarosite 的形成有益,高 Fe_2 (SO_4 )_3 集中也是有益的。相对纯 ammoniojarosite 在高 Fe_2 (SO_4 )_3 集中(>=0.05 M ) 和包含非结晶的氢氧化物讽刺 IronIs 在低 Fe_2 (SO_4 )_3 集中形成了的 melanterite 和胶体的 ammoniojarosite 下面被综合。ammoniojarosite 的免职过程能被用来从矿和另外的工业利用废水并且移开 S, Fe 和另外的有毒、有害的元素,例如作为, Cr, Hg,水里的 Pb。在标准温度和压力下面的 ammoniojarosite 和另外的 jarositeanalogs 的快速的形成为借助于黄钾铁矾和它的类似物的降水利用酸废水有好潜在的前景。 | WANG Changqiu MA Shengfeng LU Anhuai ZHOU Jiangong | 2006 | Acta Geologica Sinica(English Edition)2006，80，2： | 7 |
| 3 | Incidence and prevalence of moyamoya disease in urban China: a nationwide retrospective cohort study显示文摘Background and objective Moyamoya disease(MMD)is an increasingly recognised cause of stroke,mainly described in East Asia.China is the largest nation in Asia,but few studies reported the epidemiology of MMD,especially at a national level.We aimed to estimate the incidence and prevalence of MMD in China.Methods We performed a population-based study using data from the national databases of Urban Basic Medical Insurance between 2013 and 2016,covering approximately 0.50 billion individuals.MMD cases were identified by diagnostic code(International Classification of Diseases,10th Revision I67.5)or related diagnostic text.Results A total of 1987 MMD patients(mean age 44.45±14.30 years,female-to male ratio 1.12)were identified,representing a national crude incidence of 0.59(95%CI:0.49 to 0.68)and a prevalence of 1.01(95%CI:0.81 to 1.21)per 100000 person-years in 2016.Rates were higher in females than in males for the incidence(0.66 vs 0.52)and prevalence(1.05 vs 0.90).And the age-specific rates showed a bimodal distribution,with the highest peak in middle-aged group and the second peak in child group.Conclusions Our results confirm that MMD is relatively common in East Asians,but the rates in China were lower than those in other East Asian countries such as Japan and Korea.The unique epidemiological features,including a relatively weak female predominance and a shift in the highest peak of incidence from children to adults,revealed new sight into MMD.Further research is expected to explore the potential pathogenesis of MMD. | Yixin Sun Guoyu Zhou Jingnan Feng Lu Chen Guozhen Liu Jinxi Wang Qingliang Wang Junyou Yu Xiwang Yang Zheng Yang Pei Gao Shengfeng Wang Siyan Zhan | 2021 | Stroke & Vascular Neurology2021，6，4： | 4 |
| 4 | Selective laser melting of bulk immiscible alloy with enhanced strength:Heterogeneous microstructure and deformation mechanisms显示文摘To overcome the dimension limits of immiscible alloys produced by traditional techniques and enhance their mechanical properties,bulk Cu-Fe-based immiscible alloy with abundant nanotwins and stacking faults was successfully produced by selective laser melting(SLM).The SLM-produced bulk immiscible alloy displays a heterogeneous microstructure characterized by micro-scaledγ-Fe particles dispersed in fineε-Cu matrix with a high fraction(~92%)of high-angle grain boundaries.Interestingly,abundant nanotwins and stacking faults are generated in the interior of nano-scaledγ-Fe particles embedded withinε-Cu matrix.The heterogeneous interface of soft domains(ε-Cu)and hard domains(γ-Fe)not only induces the geometrically necessary dislocations(GNDs)but also affects the dislocation propagation during plastic deformation.Therefore,the bimodal heterogeneous interface,and the resistance of nanotwins and stacking faults to the propagation of partial dislocation make the bulk immiscible alloy exhibit an enhanced strength of~590 MPa and a good ductility of~8.9%. | Shengfeng Zhou Min Xie Changyi Wu Yanliang Yi Dongchu Chen Lai-Chang Zhang | 2022 | Journal of Materials Science & Technology2022，，9： | 3 |
| 5 | Safety,tolerability,and pharmacokinetics of BAT8001 in patients with HER2-positive breast cancer:An open-label,dose-escalation,phase I study显示文摘Background:The introductions of anti-human epidermal growth factor receptor-2(HER2)agents have significantly improved the treatment outcome of patients with HER2-positive breast cancer.BAT8001 is a novel antibodydrug conjugate targeting human epidermal growth factor receptor-2(HER2)-expressing cells composed of a trastuzumab biosimilar linked to the drug-linker Batansine.This dose-escalation,phase I study was designed to assess the safety,tolerability,pharmacokinetics,and preliminary anti-tumor activity of BAT8001 in patients with HER2-positive locally advanced or metastatic breast cancer.Methods:This trial was conducted in subjects with histologically confirmed HER2-positive breast cancer(having evaluable lesions and an Eastern Cooperative Oncology Group performance status of 0 or 1)using a 3+3 design of escalating BAT8001 doses.Patients received BAT8001 intravenously in a 21-day cycle,with dose escalation in 5 cohorts:1.2,2.4,3.6,4.8,and 6.0 mg/kg.The primary objective was to evaluate the safety and tolerability of BAT8001.Preliminary activity of BAT8001 was also assessed as a secondary objective.Results:Between March 2017 to May 2018,29 HER2-positive breast cancer patients were enrolled.The observed dose-limiting toxicities were grade 4 thrombocytopenia and grade 3 elevated transaminase.The maximum tolerated dose was determined to be 3.6 mg/kg.Grade 3 or greater adverse events(AEs)occurred in 14(48.3%)of 29 patients,including thrombocytopenia in 12(41.4%)patients,aspartate aminotransferase increased in 4(13.8%)patients,γ-glutamyl transferase increased in 2(6.9%)patients,alanine aminotransferase increased in 2(6.9%)patients,diarrhea in 2(6.9%)patients.Objective response was observed in 12(41.4%,95%confidence interval[CI]=23.5%-61.1%)and disease control(including patients achieving objective response and stable disease)was observed in 24(82.8%,95%CI=64.2%-94.2%)patients.Conclusions:BAT8001 demonstrated favorable safety profiles,with promising anti-tumor activity in patients with HER2-positive locally advanced or metastatic breast cancer.BAT8001 has the potential to provide a new therapeutic option in patients with metastatic HER2-positive breast cancer. | Ruoxi Hong Wen Xia Liye Wang Kaping Lee Qianyi Lu Kuikui Jiang Shengfeng Li Jinquan Yu Jin Wei Weijia Tang Danyang Zhou Xin An Jiajia Huang Cong Xue Xiwen Bi Yanxia Shi Zhongyu Yuan Fei Xu Shusen Wang | 2021 | Cancer Communications2021，41，2： | 2 |
| 6 | Microstructure and wear resistance of Fe-based WC coating by multi-track overlapping laser induction hybrid rapid cladding显示文摘 | Shengfeng Zhou Xiaoqin Dai Haizhong Zheng | 2011 | Optics and Laser Technology2011，，1： | 1 |
| 7 | A study of Ni-based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot 显示文摘 | ZHOU SHENGFENG HUANG YONGJUN ZENG XIAOYAN | 2008 | Applied Surface Science2008，，31： | 1 |
| 8 | A study of Ni- based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot显示文摘 | Zhou Shengfeng Huang Yongjun Zeng Xiaoyan | 2008 | Applied Surface Science2008，254，10： | 1 |
| 9 | Analytical modeling and experimental investigation of laser induction hybrid rapid cladding for Ni based WC composite coatings 显示文摘 | Shengfeng Zhou Xiaoqin Dai Haizhong Zheng | 2011 | Optics & Laser Technology2011，43，3： | 1 |
| 10 | A study of Ni-based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot 显示文摘 | ZHOU SHENGFENG HUANG YONGJUN ZENG XI- AOYAN | 2008 | Applied Surface Science2008，，254： | 1 |
| 11 | A study of Ni-based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot显示文摘 | ZHOU SHENGFENG HUANG YONGJUN ZENG XIAOYAN | 2008 | App Sur Sci2008，，254： | 1 |
| 12 | Microstructure characteristics of Ni-based WC composite coatings by laser induction hybrid rapid cladding显示文摘 | ZHOU SHENGFENG HUANG YONGJUN ZENG XIAOYAN | 2008 | Mat Sci Eng2008，，480： | 1 |
| 13 | Microstructure and wear resistance of Fe-based WC coating by multitrack overlapping laser induction hybrid rapid cladding显示文摘 | Shengfeng Zhou Xiaoqin Dai Haizhong Zheng | 2012 | Optics and Laser Technology2012，44，1： | 1 |
| 14 | Microstructure characteristics of Ni-based WC composite coatings by laser induction hybrid rapid cladding显示文摘 | Zhou Shengfeng Huang Yongjun Zeng Xiaoyan | 2008 | Mater Sci Eng A2008，480，： | 1 |
| 15 | A study of Ni-based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot 显示文摘 | Zhou Shengfeng Huang Yongiun Zeng Xiaoyan | 2008 | Applied Surface Science2008，254，10： | 1 |
| 16 | A study of Ni-based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot 显示文摘 | Zhou Shengfeng Huang Yongjun Zeng Xiaoyan | 2008 | Applied Surface Science2008，254，10： | 1 |
| 17 | Microstructure characteristics of Ni-based WC composite coatings by laser induction hybrid rapid cladding 显示文摘 | Zhou Shengfeng Huang Yongjun Zeng Xiaoyan | 2008 | Materials Science and Engineering2008，480，12： | 1 |
| 18 | A study of Ni-based WC composite coatings by laser induction hybrid rapid cladding with elliptical spot 显示文摘 | Zhou Shengfeng Huang Yongjun Zeng Xiaoyan | 2008 | Applied Surface Science2008，254，10： | 1 |
| 19 | Growth characteristics and mechanism of carbides precipitated in WC–Fe composite coatings by laser induction hybrid rapid cladding显示文摘 | Shengfeng Zhou Xiaoyan Zeng | 2010 | Journal of Alloys and Compounds2010，，2： | 1 |
| 20 | Analysis of crack behavior for Ni-based WC composite coatings by laser cladding andcrack-free realization显示文摘 | Zhou Shengfeng Zeng Xiaoyan Hu Qianwu | 2008 | Applied Surface Science2008，255，： | 1 |
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