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2篇 您的检索式:作者名="Shengyan Yin"
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1Enhanced Photocurrent Generation of Graphene/Au@ZnO Honeycomb Film显示文摘启发简历的 graphene/Au@ZnO photoelectrode 经由呼吸数字方法,在 Au@ZnO, nanospheres 在整个蜂房电影是一致地分布式的被准备了。蜂房洞的尺寸用效率完成光。有在更多的订的数组的更小的洞的蜂房电影显示出更好的 antireflective 性质。光电流的快、稳定、可逆的回答由每打开和关上事件伴随了的所有形成的 graphene/Au@ZnO 蜂房 photoelectrodes 表演。修改 Au@ZnO 的 graphene 蜂房电影能联合如果由蜂房结构,从 Au nanoparticles (NP ) 的有效充电分离,和有效电子转移由 graphene 提供了,收获的增加的光的优点。Au@ZnO- 修改了 graphene 蜂房电影比修改 Au@ZnO 的 graphene 比修改 ZnO 的 graphene 蜂房电影和光电流产生的三方面的增加显示出光电流产生的双重的增加光滑的电影分别地。合理设计和工程多,有在一个混合启发简历的结构抓住伟人的不同功能的部件为进一步有效的太阳能变换设备答应。Hang Sun Qinrong He Shengyan Yin Kongliang Xu 2017Chinese Journal of Chemistry2017,35,10:4
2Chemokine Ligand 13 Expression is Abundant in the Tumor Microenvironment and Indicates Poor Prognosis of Kidney Clear Cell Carcinoma显示文摘The chemokine ligand 13-chemokine receptor 5(CXCL13-CXCR5)axis has been characterized as a critical tumor-promoting signaling pathway in the tumor microenvironment(TME)in multiple types of solid tumors.In this study,we analyzed the expression profile of CXCL13 in kidney clear cell carcinoma(KIRC)and its correlation with tumor-infiltrating immune cells(TIICs).A monoclonal antibody against CXCL13 with high affinity and purity was generated in our lab for western blot and immunohistochemistry(IHC).Bioinformatic analysis was performed based on bulk-seq data from the Cancer Genome Atlas(TCGA)-KIRC and single-cell RNA-seq data from scRNASeqDB and PanglaoDB.Results showed that high CXCL13 expression in TME was associated with shorter progression-free survival(PFS),disease-specific survival(DSS),and overall survival(OS).KIRC cell lines,as well as several other cancer cell lines,had negative CXCL13 expression.IHC staining from the Human Protein Atlas(HPA)and our tissue array indicated that CXCL13 might be mainly expressed by TIICs,but not KIRC tumor cells.CXCL13 expression was strongly and positively correlated withγδT cell abundance in TME.Besides,γδT cell infiltration was associated with poor survival of KIRC.Methylation 450k array data showed that CXCL13 promoter hypomethylation was common in TIICs.The methylation level of cg16361705 within the CXCL13 promoter might play an important role in modulating CXCL13 transcription.In conclusion,our study revealed that CXCL13 expression andγδT cell infiltration in TME is associated with unfavorable survival of KIRC.TIICs,most possiblyγδT cells,are the dominant source of CXCL13 in KIRC TME.MENGDAN WU MENGYAO SUN QINHUAI LAI YIN LU YUYIN FU YUJIA PENG WEIRONG LAI LISHI ZENG SHENGYAN ZHAO YUYAN LI ZHIXIONG ZHANG XIAOFENG CHEN FAN QIAO YIWEN ZHANG SHIJIE ZHOU LANTU GOU JINLIANG YANG 2021BIOCELL2021,45,3:0
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