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| 1 | 补虚药的药理学研究思路与方法显示文摘补虚药是中药学、中药药理学等课程的重要章节之一。为了让学生更好地掌握该章节的研究思路与方法 ,并将其应用到科研及中医临床中,本文拟从补虚药调节神经-内分泌-免疫网络的作用、补虚药对物质代谢的影响、探索虚证动物模型、不同类型补虚药的研究各有侧重四个方面对补虚药的研究思路和方法进行探索,以期建立针对补虚药的科学研究方法与手段,为阐明中医理论下补虚药治疗疾病的科学内涵及指导中医临床科学合理用药打下基础。 | Sarmad Sheraz Jadoon 丁莉 张舜波 李凡 游秋云 | 2018 | 中国医药导报2018，15，10： | 23 |
| 2 | 碱处理提取竹黄纤维的响应曲面优化显示文摘采用响应曲面设计(Box-Behnken设计)优化竹纤维的提取工艺。以碱和脂肪醇聚氧乙烯醚(JFC)渗透剂对竹片进行沸煮,并结合机械碾压提取竹黄纤维,以碱浓度为0.5%~0.7%、JFC浓度为0.1%~0.3%、沸煮时间为1.5~2.5h为考察因素,采用响应曲面法,以竹纤维断裂强度、提取率、直径和摩擦系数为响应值,建立数学模型,获得综合性能最佳工艺。并采用扫描电镜观察不同工艺处理的竹纤维的纵向结构。结果表明:最优提取工艺为碱浓度为0.7%、JFC浓度为0.3%、沸煮时间为2.5h,此时纤维的综合性能最佳,拉伸断裂强度为386.25MPa,直径为191.79μm,摩擦系数为0.206,与响应曲面预测值(断裂强度为405.08 MPa,直径为175.59μm,摩擦系数为0.191)接近。响应曲面法优化得到的竹纤维性能较好,并能很好地预测试验结果,断裂强度与预测值偏差4.6%,摩擦系数与预测值偏差7.8%,直径与预测值偏差9.2%。SEM表明:碱处理、JFC处理和沸煮时间对纤维表面的胶质有影响,碱浓度为0.5%、JFC浓度为0.3%、沸煮时间为2.5h时有利于竹纤维表面胶质的去除。 | 林天扬 王春红 YOUSFANI Sheraz Hussain Siddique 王威 钱晓明 徐志伟 | 2018 | 复合材料学报2018，35，4： | 18 |
| 3 | 竹原纤维的分级提取及其性能显示文摘为探究不同竹龄及不同取材部位竹原纤维性能的变异规律,以不同竹龄、不同部位的慈竹为原料,采用物理-化学结合的方法提取竹原纤维,并分别测定竹原纤维的化学组成、纤维的表面形貌、纤维的密度、吸湿性能、拉伸强度。结果表明:相同部位竹原纤维,随竹龄的增加,纤维的密度先增大后减小,纤维的回潮率先减小后增大;相同竹龄竹原纤维,随着距地高度的增加,纤维密度增加,回潮率先稍有降低后升高。3年生慈竹梢部纤维密度最大,为1.70 g/cm3,4年生的基部纤维密度最小,为1.51 g/cm3。3年生慈竹中部纤维回潮率最低,为12.94%,其不同部位竹原纤维拉伸强度较为稳定,4年生中部竹原纤维拉伸强度最大,为787.42 MPa。 | 王春红 陈祯 李园平 YOUSFANI Sheraz Hussain Siddique 陈雅颂 | 2017 | 纺织学报2017，38，11： | 9 |
| 4 | 稻壳纤维粒径和掺量分数对水泥复合材料性能的影响显示文摘以稻壳纤维(Rice husk fiber,RHF)为增强材料,以水泥为基体,制备了RHF/水泥基复合材料。研究了粒径对RHF在水泥基体中分散性能的影响;并以RHF粒径和掺入质量比为考察因素,采用响应曲面法,以RHF/水泥基复合材料的密度、抗折强度、含水率、吸水率和导热系数为响应值,建立数学模型,对RHF/水泥基复合材料的成型工艺进行优化设计。结果表明:RHF的粒径越小,在水泥基体中分散性能越好,粒径为150μm的RHF分散系数达到最大值,为0.981;响应曲面模型分析表明RHF的粒径为150μm、掺入质量为水泥质量的3%时,RHF/水泥基复合材料的性能达到最优,此时RHF/水泥基复合材料的密度为1 559.26kg/m3,抗折强度为9.38 MPa,含水率为7.05%,吸水率为16.71%,导热系数为0.50 W/(m·K),达到了建筑行业标准JC/T411—2007的要求。 | 王春红 支中祥 任子龙 SHERAZ Hussain Siddique Yousfani 王威 钱晓明 | 2018 | 复合材料学报2018，35，6： | 8 |
| 5 | 基于遗传算法的NoC路径分配算法显示文摘在片上网络中实现通信流明确的应用,通常在编译过程中静态分配路径资源,并把路径分配算法嵌入到映射算法中综合考虑.针对现有基于遗传算法的片上网络路径分配算法,引入了一种完整路径均匀交叉算子,来改善现有算法中路径交叉不充分的问题.实验结果显示:使用新算子的路径分配算法优化了现有算法的结果,减少了计算时间. | 岳培培 刘建 Sheraz Anjum 陈杰 | 2008 | 微电子学与计算机2008，25，4： | 5 |
| 6 | 一种用于GPS信号快速捕获的自适应算法(英文)显示文摘采用聂孟-皮尔逊准则,以发现概率为性能指标,对基于FFT非相干累加的GPS信号捕获算法的性能进行了详细的理论推导,给出了该种方法的理论性能上界,提出了一种用于快速捕获的高效自适应算法,并通过系统仿真对理论结果进行了验证.对实际情况中概率分布的合理近似使理论分析过程得以简化,并使判决门限可根据噪声方差及累加次数进行自适应调整的算法可以直接应用于实时GPS接收机的设计. | 李金海 巴晓辉 SHERAZ Anjum 陈杰 | 2007 | 电子器件2007，30，3： | 5 |
| 7 | Continuous wound infusion of local anaesthetic agents following colorectal surgery:Systematic review and meta-analysis显示文摘AIM:To provide a specifi c review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparoto-my for major colorectal surgery. METHODS: Medline, Embase, trial registries, conference proceedings and article reference lists were searched to identify randomised, controlled trials of continuous wound infusion of local anaesthetic agents following colorectal surgery. The primary outcomes were opioid consumption, pain visual analogue scores (VASs), return to bowel function and length of hospital stay. Weighted mean difference were calculated for continuous outcomes. RESULTS: Five trials containing 542 laparotomy wounds were eligible for inclusion. There was a sig- nificant decrease in post-operative pain VAS at rest on day 3 (weighted mean difference: -0.43; 95% CI: -0.81 to -0.04; P = 0.03) but not on post-operative day 1 and 2. Local anaesthetic infusion was associated with a signifi cant reduction in pain VAS on movement on all three post-operative days (day 1 weighted mean difference: -1.14; 95% CI: -2.24 to -0.041; P = 0.04, day 2 weighted mean difference: -0.97, 95% CI: -1.91to -0.029; P = 0.04, day 3 weighted mean difference: -0.61; 95% CI: 1.01 to -0.20; P = 0.0038). Local an- aesthetic wound infusion was associated with a signifi - cant decrease in total opioid consumption (weighted mean difference: -40.13; 95% CI: -76.74 to -3.53; P = 0.03). There was no signifi cant decrease in length of stay (weighted mean difference: -20.87; 95% CI: -46.96 to 5.21; P = 0.12) or return of bowel function (weighted mean difference: -9.40; 95% CI: -33.98 to 15.17; P = 0.45). CONCLUSION: The results of this systematic re- view and meta-analysis suggest that local anaesthetic wound infusion following laparotomy for major color- ectal surgery is a promising technique but do not pro- vide conclusive evidence of benefi t. Further research is required including cost-effectiveness analysis. | Alan Karthikesalingam Stewart R Walsh Sheraz R Markar Umar Sadat Tjun Y Tang Charles M Malata | 2008 | World Journal of Gastroenterology2008，14，34： | 4 |
| 8 | 乌拉草/棉/维纶复合纱线的开发与性能显示文摘针对乌拉草/棉/维纶赛络纺包芯纱存在毛羽较多和条干较差等问题,加装导纱器引入外包缠纱,设计一种改善其条干和减少毛羽的新型纺纱方法:改进型赛络菲尔纺。对影响纱线性能较大的纱线捻系数与导纱间距进行了实验,并以断裂强度、断裂伸长率、毛羽指数和条干均匀度为性能评价指标,对改进型赛络菲尔纺制备的乌拉草/棉/维纶复合纱的工艺进行模糊综合评价。结果表明:捻系数对纱线性能影响顺序依次为400、380、360、340;改进型赛络菲尔纺在单纱间距为10 mm,捻系数为400时,复合纱的综合性能最好,与传统赛络菲尔纺工艺制备的包芯纱对比,毛羽指数下降了73.49%,条干不匀率减小了29.05%。 | 王利军 王春红 龙碧璇 YOUSFANI Sheraz Hussain Siddique 徐磊 | 2017 | 纺织学报2017，38，12： | 4 |
| 9 | 基于自适应锁相环的高动态GPS信号载波跟踪算法显示文摘提出了一种基于四维卡尔曼滤波的自适应锁相环算法,并将该算法用于高动态GPS信号的载波跟踪.详细推导了卡尔曼滤波与数字锁相环之间的等效性,并给出了相应的环路更新步骤.仿真结果表明,该算法相对于采用固定增益数字锁相环的算法明显地降低了载波跟踪过程的均方根频率误差,提高了接收机的测速精度. | 李金海 巴晓辉 SHERAZ Anjum 陈杰 | 2007 | 电子器件2007，30，4： | 4 |
| 10 | 关节软骨Osterix蛋白表达强度对膝关节骨性关节炎形态学变化的影响显示文摘目的:探讨Osterix蛋白在关节软骨中的表达强度对膝关节骨性关节炎形态学变化的影响。方法:选取44例因膝关节骨性关节炎行人工全膝关节置换术的患者,取术中去除的股骨髁软骨组织,磨损较重的一侧为负重区(实验组),磨损较轻的一侧为非负重区(对照组)。通过HE染色评估软骨组织形态学变化,再将负重区软骨分为中度磨损组和重度磨损组,通过免疫组织化学检测并比较Osterix蛋白在三组中的表达强度。结果:大体观察下,负重区标本表面粗糙,大量软骨丢失,软骨下骨板暴露,色泽灰暗,甚至可见溃疡灶形成;非负重区标本表面光滑平整,富有光泽,软骨完整且呈乳白色,未见溃疡灶。通过HE染色后可见负重区软骨面残缺不齐,过渡层出现裂隙,软骨细胞分布紊乱,潮线不完整,软骨下骨排列不均;非负重区组软骨表面较为平整,软骨细胞数量多,胞质完整均匀。免疫组化染色可见Osterix蛋白在非负重区软骨中显著表达,在负重区软骨表达较少。统计学分析显示,重度磨损组Osterix蛋白阳性表达率小于中度磨损组,且两者均小于非负重区组(均P<0.05)。结论:Osterix蛋白参与了关节软骨退行性变过程,其在软骨细胞中的表达强度会随着软骨磨损程度的增加而减弱。 | 郭凤英 张晨 李燕 张晋宁 杨天翔 张博文 陈德胜 | 2021 | 陕西医学杂志2021，50，3： | 4 |
| 11 | 用于片上网络的网络接口设计显示文摘提出一种用于由双通道路由器组成的片上网络系统的网络接口。该网络接口符合AMBA总线协议,能根据IP核的通信请求,自动选取通信方式,向IP核隐藏通信细节,充分利用双通道路由器中控制包通道与数据包通道分离的特点,方便系统编程。使用SMIC0.13μm工艺综合后,该网络接口的面积仅为0.3mm2。 | 岳培培 陈杰 刘建 Sheraz Anjum | 2009 | 计算机工程2009，35，10： | 3 |
| 12 | 应用于片上网络的双通道路由器显示文摘提出了一种新颖的应用于片上网络的双通道路由器,该路由器使用分开的数据包通道和控制包通道,能够在相同的约束下达到更好的性能。通过对随机通信流和MPEG-4通信流的仿真,可知双通道路由器系统中两种传输包不会相互影响,且相比于传统的单通道路由器和虚通道路由器,使用双通道路由器可以达到更好的吞吐量和平均延时性能。每个路由器的电路规模仅为2.05万门,在SMIC0.13μmCMOS工艺下,综合面积仅需0.103mm2。 | 岳培培 陈杰 刘建 SHERAZ ANJUM | 2009 | 电子科技大学学报2009，38，2： | 3 |
| 13 | Point-of-care testing in the diagnosis of gastrointestinal cancers: Current technology and future directions显示文摘Point-of-care(POC) tests enable rapid results and are well established in medical practice.Recent advances in analytical techniques have led to a new generation of POC devices that will alter gastrointestinal diagnostic pathways.This review aims to identify current and newtechnologies for the POC diagnosis of gastrointestinal cancer.A structured search of the Embase and Medline databases was performed.Papers reporting diagnostic tests for gastrointestinal cancer available as a POC device or containing a description of feasibility for POC application were included.Studies recovered were heterogeneous and therefore results are presented as a narrative review.Six diagnostic methods were identified(fecal occult blood, fecal proteins, volatile organic compounds, pyruvate kinase isoenzyme type M2, tumour markers and DNA analysis).Fecal occult blood testing has a reported sensitivity of 66%-85% and specificity greater than 95%.The others are at a range of development and clinical application.POC devices have a proven role in the diagnosis of gastrointestinal cancer.Barriers to their implementation exist and the transition from experimental to clinical medicine is currently slow.New technologies demonstrate potential to provide accurate POC tests and an ability to diagnose gastrointestinal cancer at an early stage with improved clinical outcome and survival. | Jeremy R Huddy Melody Z Ni Sheraz R Markar George B Hanna | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 14 | Global myocardial strain assessment by different imaging modalities to predict outcomes after ST-elevation myocardial infarction:A systematic review显示文摘AIM: To conduct a systematic review relating myocardial strain assessed by different imaging modalities for prognostication following ST-elevation myocardial infarction(STEMI).METHODS: An online literature search was performed in Pub Med and OVID® electronic databases to identify any studies that assessed global myocardial strain parameters using speckle-tracking echocardiography(STE) and/or cardiac magnetic resonance imaging(CMR) techniques [either myocardial tagging or feature tracking(FT) software] in an acute STEMI cohort(days 0-14 post-event) to predict prognosis [either development of major adverse cardiac events(MACE)] or adverse left ventricular(LV) remodelling at follow-up(≥ 6 mo for MACE,≥ 3 mo for remodelling). Search was restricted to studies within the last 20 years. All studies that matched the pre-defined search criteria were reviewed and their results interpreted. Due to considerable heterogeneity between studies,metaanalysis was not performed.RESULTS: A total of seven studies(n = 7) were identified that matched the search criteria. All studies used STE to evaluate strain parameters- five(n = 5) assessed global longitudinal strain(GLS)(n = 5),one assessed GLS rate(GLS-R)(n = 1) and one assessed both(n = 1). Three studies showed that GLS independently predicted the development of adverse LV remodelling by multivariate analysis- odds ratio between 1.19(CI: 1.04-1.37,P < 0.05) and 10(CI: 6.7-14,P < 0.001) depending on the study. Four studies showed that GLS predicted the development of MACE- hazard ratio(HR) between 1.1(CI: 1-1.1,P = 0.006) and 2.34(1.10-4.97,P < 0.05). One paper found that GLS-R could significantly predict MACEHR 18(10-35,P < 0.001)- whilst another showed it did not. GLS <-10.85% had sensitivity/specificity of 89.7%/91% respectively for predicting the development of remodelling whilst GLS <-13% could predict the development of MACE with sensitivity/specificity of 100%/89% respectively. No suitable studies were identified that assessed global strain by CMR tagging or FT techniques.CONCLUSION: GLS measured acutely post-STEMI by STE is a predictor of poor prognosis. Further research is needed to show that this is true for CMR-based techniques. | Abhishek Shetye Sheraz A Nazir Iain B Squire Gerald P McCann | 2015 | World Journal of Cardiology2015，7，12： | 2 |
| 15 | Laparoscopic versus open colorectal resection in the elderly population显示文摘 | Katherine Grailey Sheraz R. Markar Alan Karthikesalingam Rima Aboud Paul Ziprin Omar Faiz | 2013 | Surgical Endoscopy2013，，1： | 2 |
| 16 | Detection and management of oligometastatic disease in oesophageal cancer and identification of prognostic factors: A systematic review显示文摘BACKGROUND Oesophageal cancer is the eighth most common cancer worldwide.The prognosis of oesophageal cancer patients still remains poor.The 5-year survival rate rarely exceeds 5%in case of metastatic disease.Some patients may however present with oligometastasis which can be treated with loco-regional therapy.AIM To assess the current practice regarding the management of patients with oligometastatic oesophageal cancer and identify prognostic factors affecting survival following treatment for oligometastasis.METHODS A systematic search of the literature was performed in Cochrance Library,MEDLINE and EMBASE databases from September 1950 to January 2019.Relevant electronic databases were searched for studies assessing the clinical outcome of oligometastasis.RESULTS A total of 14 publications were included,of which 12 studies assessing metachronous oligometastasis and 2 on synchronous oligometastasis.All included articles evaluated the specific outcomes of metastasis,management modality and survival outcomes.The majority of the patients presented with oesophageal squamous cell carcinoma.The median disease free interval(time to recurrence)in patients was 19.6 mo and the overall survival reached 30.8 months.Unfavourable prognostic factors were assessed in eight studies and included time to recurrence<12 mo,large diameter pulmonary lesions(>20 mm),disease free interval(DFI)<12 mo,extra-pulmonary metastasis,primary tumour pathological stage III/IV.CONCLUSION Oligometastatic oesophageal cancer in selected patients is amenable to locoregional treatment,and the overall survival of this patient cohort may be improved with patient and tumour-specific treatments. | Sara Jamel Karina Tukanova Sheraz Markar | 2019 | World Journal of Gastrointestinal Oncology2019，11，9： | 2 |
| 17 | 聚乙烯醇乳液改性对汉麻秸秆纤维/水泥基复合材料性能的影响显示文摘为解决汉麻秸秆纤维/水泥基复合材料力学性能较差的问题,本文提出采用聚乙烯醇(PVA)乳液对汉麻秸秆纤维/水泥基复合材料进行改性。在优化秸秆纤维的粒径和掺入量后,采用PVA乳液与秸秆纤维和水泥进行共混成型,制备了改性后的汉麻秸秆纤维/水泥基复合材料。研究了不同质量比的PVA乳液对汉麻秸秆纤维/水泥基复合材料的抗折强度、密度、比强度和弯曲韧性的影响,通过含水率、吸水率及红外光谱测试揭示了PVA乳液对汉麻秸秆纤维/水泥基复合材料的改性机制。结果表明:汉麻秸秆纤维粒径为1700μm及掺入量为12%时,秸秆纤维对汉麻秸秆纤维/水泥基复合材料的增强作用最好。随着PVA乳液质量比的增加,改性后汉麻秸秆纤维/水泥基复合材料的密度逐渐减小,弯曲韧性逐渐提高。当PVA乳液质量比为4.8%时,相较于未改性的汉麻秸秆纤维/水泥基复合材料,改性后的汉麻秸秆纤维/水泥基复合材料抗折强度和比强度分别提高了17.17%和20.50%。通过PVA乳液改性使汉麻秸秆纤维/水泥基复合材料中秸秆纤维与水泥之间的界面得到改善,并缓解了秸秆纤维对水泥水化反应的阻碍作用。 | 王春红 左祺 支中祥 徐磊 SARANI Zakaria SHERAZ Hussain Siddique Yousfani | 2021 | 复合材料学报2021，38，5： | 2 |
| 18 | 急性上消化道出血显示文摘每年,每10万人中就有约100例发生上消化道(食道、胃和十二指肠)出血“。这是一个具有较高病死率的内科急症。2007年英国的一项调査发现,上消化道出血的总病死率为10%。消化性溃疡是上消化道出血最常见的原因(框图1),这一实践指南为上消化道出血的初期处理以及消化性溃疡出血的后续管理提供了指导。 | Emma Sverden Sheraz R Markar Lars Agreus Jesper Lagergren 龚亮(译) 吴东(校) 无 | 2019 | 英国医学杂志中文版2019，22，7： | 1 |
| 19 | Brand Management,What is Next? Word of Mouth (WOM) as a 6th Element of Promotional Mix and IMC 显示文摘 | Ahmed Nadeem Haroon Rashid Sheraz Ahamed Khan Niazi | 2011 | Interdisciplinary Journal of Contemporary Research In Business2011，4，2： | 1 |
| 20 | Endovascular Treatment Options in the Management of Lower Limb Deep Venous Thrombosis显示文摘 | Sarfraz Ahmed Nazir Arul Ganeshan Sheraz Nazir Raman Uberoi | 2009 | CardioVascular and Interventional Radiology2009，，5： | 1 |
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