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| 1 | Antiviral activity of quercetin-3-β-O-D-glucoside against Zika virus infection显示文摘Dear Editor,The 2015–2016 outbreak of Zika virus(ZIKV)fever,first reported in Brazil during early 2015(Zanluca et al.,2015),has infected millions of people and is a global public health concern.ZIKV infections are associated with fetal microcephaly,as well as neurological | gary wong shihua he vinayakumar siragam yuhai bi majambu mbikay michel chretien xiangguo qiu | 2017 | Virologica Sinica2017，32，6： | 5 |
| 2 | Development of a reverse transcription quantitative polymerase chain reaction-based assay for broad coverage detection of African and Asian Zika virus lineages显示文摘The Zika virus(ZIKV) is an arbovirus that has spread rapidly worldwide within recent times. There is accumulating evidence that associates ZIKV infections with Guillain-Barré Syndrome(GBS) and microcephaly in humans. The ZIKV is genetically diverse and can be separated into Asian and African lineages. A rapid, sensitive, and specific assay is needed for the detection of ZIKV across various pandemic regions. So far, the available primers and probes do not cover the genetic diversity and geographic distribution of all ZIKV strains. To this end, we have developed a one-step quantitative reverse transcription polymerase chain reaction(qRT-PCR) assay based on conserved sequences in the ZIKV envelope(E) gene. The detection limit of the assay was determined to be five RNA transcript copies and 2.94 × 10^(–3) 50% tissue culture infectious doses(TCID50) of live ZIKV per reaction. The assay was highly specific and able to detect five different ZIKV strains covering the Asian and African lineages without nonspecific amplification, when tested against other flaviviruses. The assay was also successful in testing for ZIKV in clinical samples. Our assay represents an improvement over the current methods available for the detection ZIKV and would be valuable as a diagnostic tool in various pandemic regions. | Yang Yang Gary Wong Baoguo Ye Shihua Li Shanqin Li Haixia Zheng Qiang Wang Mifang Liang George F Gao Lei Liu Yingxia Liu Yuhai Bi | 2017 | Virologica Sinica2017，32，3： | 3 |
| 3 | Evidence for metasomatic mantle carbonatitic magma extrusion in Mesoproterozoic ore-hosting dolomite rocks in the middle Kunyang rift, central Yunnan, China显示文摘The Kunyang rift lying on the western margin of the Yangtze platform is a rare Precambrian Fe-Cu mineralization zone. WudingLufeng basin that is an important part of the zone is located on the west edge in the middle of the rift. The most important ore-hosting rocks are Mesoproterozoic dolomite rocks in the basin controlled by a ring fracture system, which is a fundamental structure of the basin. Plenty of silicate minerals and acicular apatite, feldspar phenocrysts and small vesicular, flown line and flown plane structures, melt inclusion and high temperature fluid inclusion found in most ore-hosting dolomites suggest that this kind of rocks could not be sedimentary dolomite, marble or hydrothermal carbonate rocks. The Zr/Hf and Nb/Ta values of the rocks are identical with those of associated mantle-derived rocks, and vary widely. For the monomineral dolomite, d18OSMOW‰ = +5.99 to +18.4 and d13CPDB‰ = à3.01 to +0.94, which fall within the range for all carbonatitic volcanic rocks of the world. As for the accessory minerals, the values of d18OSMOW‰ of magnetite (=+3.47 to +5.99‰) are close to that of the mantle (<5.7%), and the d34S‰ values of sul?des (à5.09 to +5.78, averaging +1.50) are close to that of meteorite. For all the ore-bearing dolomite rocks, eNd = +0.19 to +2.27, and the calculated ISr = 0.699143, while for the associated mantle-derived rocks, eNd = +3.18 to +3.72. All the data suggest that the mineral assemblage is not only igneous but also of metasomatic mantle origin. And the presence of acicular apatite indicates that the rocks were formed by magma rapidly cooling. And the phenocryst texture and vesicular, flown and ropy and pyroclastic structures suggest that the igneous rocks were extrusive. Therefore, the ore-bearing dolomite rocks are carbonatitic volcanic rocks. This conclusion implies that most iron and copper ore deposits hosted in the dolomite rocks should be of the carbonatite type. | Yongbei Zhang Hua Bi Longshi Yu Shihua Sun Jiaxiang Qiu Chengyan Xu Hao Wang Renjing Wang | 2008 | Progress in Natural Science:Materials International2008，18，8： | 2 |
| 4 | Mobile Network Computer Can Better Describe The Future of Information Society显示文摘In the paper, we illustrate the importance of the concept of mobile network computer from a technological perspective. Because of the usefulness of mobile network computers, with the growth of the Internet of things, mobile network computers may include not only TV box audio-visual equipment, wireless household appliances, and mobile communication equipment, but may also include devices such as intelligent foot rings, smart watches, smart glasses, smart shoes and smart coats. Considering the different types of networks, e.g. IP multimedia Subsystem(IMS), we explain why some network elements are inaccurate and misleading from a technological perspective. We aim to popularize the concept of mobile network computers for its accuracy and importance, which better define modern mobile terminals and reflects the nature of multiple mobile terminals based on the structure of their integrated computers and the capabilities of processing multimedia. In the computer and Internet age, network computers and mobile network computers are the main terminals of fixed and mobile networks, respectively. Therefore, based on the concept of mobile network computers, we discuss the future of information society. | Zhaoming Guo Yi Jiang Shihua Bi | 2016 | China Communications2016，13，12： | 1 |
| 5 | Zika virus in the testes: should we be worried?显示文摘 | Gary Wong Shihua Li Lei Liu Yingxia Liu Yuhai Bi | 2017 | Protein & Cell2017，8，3： | 1 |
| 6 | Natural killer cells are activated and play a protective role against ZIKA virus infection in mice显示文摘Zika virus(ZIKV)is a mosquito-borne Flavivirus that was responsible for an epidemic in the Americas during 2015–2016[1].ZIKV infections in adults have been linked to Guillain-Barrésyndrome[2,3],as well as abnormalities such as abortion,stillbirth,and microcephaly in some cases[4].In addition,we have reported that ZIKV infect testicular stem-like peritubular | Xuefeng Duan Shihua Li Gary Wong Dongfang Wang Haoyu Wang Jiao Lu Yuhai Bi Xuancheng Lu Yi Shi Jinghua Yan Min Fang George Fu Gao | 2017 | Science Bulletin2017，62，14： | 0 |
| 7 | Detection Probability for Moving Ground Target of Normal Distribution Using an Imaging Satellite显示文摘The detection probability for a moving target is an important issue, we aim to discuss the detection probability for a moving ground target such as military vehicles using a visible light imaging satellite. First, a basic detection model for a regional ground target using a satellite was discussed and the probability of detection was calculated. Next, a basic model for the recognition of a ground target using a visible light imaging satellite was developed based on above model. Then, a basic model of the detection probability for a moving ground target using a visible light imaging satellite was studied. As the normal distribution has the maximum entropy, the normal distribution of a moving ground target such as military vehicles was analyzed, and based on our conclusions, a basic probability model for the detection of a moving ground target using a visible light satellite was developed. Finally, the simulation was carried on. | GUO Zhaoming JIANG Yi BI Shihua | 2018 | Chinese Journal of Electronics2018，27，6： | 0 |
| 8 | Trigger control characteristics of fuze-recoil simulation system based on electromagnetic launcher显示文摘Fuze is the information processing and control unit of the ammunition, so the quality of the fuze becomes one of the most important aspects of ammunition detection. Since using recoil force is a common method to the arm fuze, its dynamic simulation test has always been the focus of the fuze test research. A new fuze recoil environmental simulation method is proposed based on the electromagnetic launcher. Then the trigger control characteristics of the fuze recoil simulation system and the influence of the trigger position on the recoil force are studied. The results of the study show that although the pulse width of the armature force curve can be changed by adjusting the trigger position, due to the limit of the range, there also exists the contradiction that the electromagnetic pulse width gets narrow with the increase of electromagnetic force peak. Thus, it cannot meet the requirements of the fuze launch recoil simulation. In order to make the recoil force close to the actual environment, the multi-stage trigger control characteristics are analyzed, and the influence of trigger position on recoil environmental force characteristics is studied. Then a fuze launch recoil environmental simulation platform is established and continuous electromagnetic force is achieved by using the trigger strategy.Finally, the experiment is performed to simulate the fuze launch recoil environment and show the feasibility and effectiveness of the proposed theoretical analysis. The major research work of this paper includes studying the composition and basic principle of the simulation system, establishing a launch model to analyze the single-stage and multi-stage coil fuze launch recoil characteristics,designing the test device to verify the correctness and validity of the research. This paper draws the conclusions that the feasibility of the fuze launch environmental simulation based on the electromagnetic launcher is verified, the trigger position has a great influence on force peak continuity, the problems of low maximum overload peak and short peak duration in the multi-stage coil fuze launch environmental simulation can be effectively solved through adjusting the trigger position, the system has creative and extensive application prospects. | Wenhao Wang Shihua Bi Hongjun Xiang Chao Zhan Xichao Yuan | 2017 | Journal of Systems Engineering and Electronics2017，28，3： | 0 |
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