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| 1 | 经皮穴位电刺激联合结肠起搏治疗老年功能性便秘的临床应用显示文摘目的探讨经皮穴位电刺激联合结肠起搏同步协同疗法治疗老年功能性便秘患者的临床疗效。方法根据罗马Ⅳ标准选择118例老年功能性便秘患者,其中治疗组60例,平均年龄(81.45±8.47)岁;对照组58例,平均年龄(79.33±9.31)岁;两组患者在服乳果糖的基础上,治疗组加用经皮穴位(左右天枢及足三里)电刺激联合结肠起搏治疗4周,两组治疗前后均使用便秘患者症状自评量表(PAC-SYM)评分,主要症状评分指标及总分均行分析并行疗效对比。结果治疗组有效率为83.3%,对照组有效率为67.2%,两组治疗前后症状评分均有改善(P<0.05)。说明经皮穴位刺激联合结肠起搏同步协同疗法对老年功能性便秘患者可有效改善症状。两组总有效率对比差异有统计学意义(P<0.05)。结论通过经皮穴位电刺激联合结肠起搏疗法能有效改善老年功能性便秘患者的排便困难症状。 | 邓罡 徐丽姝 陈晋 Shirong Cui | 2020 | 实用医学杂志2020，36，19： | 9 |
| 2 | A novel typerail-coil hybrid electromagnetic launcher显示文摘 | Yang Shirong Wang Ying Cui Shanbao | 2005 | IEEE Transac-tions on Magnetics2005，41，1： | 1 |
| 3 | Identification and Characterization of a Novel Thymus Aging Related Protein Rwdd1显示文摘By using DDRT-PCR and EST segment ligation,a novel mouse thymus involution related gene Rwdd1 was identified. The reading frame encoded a protein of 243 amino acid residues which contained an RWD domain at the N terminus. Rwdd1 expression in thymus was decreased in aged and oxidatively stressed mice. It was found to be expressed extensively in thymocytes and thymic epithelial cells. The expression level of Rwdd1 could affect the transactivation activity of androgen receptor (AR) in transiently transfected thymic epithelial cells. However,no direct interaction could be detected by fluorescence resonance energy transfer (FRET) analysis. In conclusion,Rwdd1 is a thymus involution related protein that may indirectly affect AR signaling pathway. | Ning Kang Lian Duan Long Tang Shirong Liu Chunman Li Yonghai Li Qingfeng Liu Yu Hu Lianxian Cui Wei He | 2008 | Cellular & Molecular Immunology2008，5，4： | 1 |
| 4 | DHD4,a CONSTANS-like family transcription factor,delays heading date by affecting the formation of the FAC complex in rice显示文摘Heading date(or flowering time)is one of the most important agronomic traits in rice,influencing its regional adaptability and crop yield.Many major-effect genes for rice heading date have been identified,but in practice they are difficult to be used for rice molecular breeding because of their dramatic effects on heading date.Genes with minor effects on heading date,which are more desirable for fine-tuning flowering time without significant yield penalty,were seldom reported.In this study,we identified a new minor-effect heading date repressor,Delayed Heading Date 4(DHD4).The dhd4 mutant shows a slightly earlier flowering phenotype without a notable yield penalty compared with wild-type plants under natural long-day conditions.DHD4 encodes a CONSTANS-like transcription factor localized in the nucleus.Molecular,biochemical,and genetic assays show that DHD4 can compete with 14-3-3 to interact with OsFD1,thus affecting the formation of the Hd3a-14-3-3-OsFD1 triprotein FAC complex,resulting in reduced expression of OsMADS14 and OsMADS15,and ultimately delaying flowering.Taken together,these results shed new light on the regulation of flowering time in rice and provide a promising target for fine-tuning flowering time to improve the regional adaptability of rice. | Maohong Cai Shanshan Zhu Mingming Wu Xiaoming Zheng Jiachang Wang Liang Zhou Tianhui Zheng Song Cui Shirong Zhou Chaonan Li Huan Zhang Juntao Chai Xinyue Zhang Xin Jin Zhijun Cheng Xin Zhang Cailin Lei Yulong Ren Qibing Lin Xiuping Guo Lei Zhao Jie Wang Zhichao Zhao Ling Jiang Haiyang Wang Jianmin Wan | 2021 | Molecular Plant2021，14，2： | 1 |
| 5 | Rwdd1,a Thymus Aging Related Molecule,Is a New Member of the Intrinsically Unstructured Protein Family显示文摘We had previously identified a novel protein termed Rwdd1 whose expression in thymus is decreased in aged or oxidatively stressed mice. In the present study, we found that Rwdd1 expressed in both prokaryotic and eukaryotic cells showed a slower migration rate on SDS-PAGE gel. In addition, Rwdd1 was more sensitive to proteinase proteolysis. Furthermore, being a highly acidic protein which contains an RWD domain, Rwdd1 shared a high level of sequence similarity with Gir2, a member of the intrinsically unstructured protein (IUP). These findings suggest that Rwdd1 is a novel member of the IUP family. | Ning Kang Dai Chen Li Wang Lian Duan Shirong Liu Long Tang Qingfeng Liu Lianxian Cui Wei He | 2008 | Cellular & Molecular Immunology2008，5，5： | 0 |
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