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| 1 | Improved performance of aluminum pigments encapsulated in hybrid inorganic-organic films显示文摘An organic silane acrylate resin(PMBK) was synthesized by free-radical solution polymerization using methyl methacrylate,butyl acrylate and(3-methacryloxypropyl)trimethoxysilane as monomers.Aluminum(Al) particles were then encapsulated in inorganic-organic hybrid films that were prepared by hydrolysis and condensation of PMBK and tetraethyl orthosilicate(TEOS) on the surface of Al pigments.Characterization results showed that PMBK and TEOS could simultaneously hydrolyze and condense with hydroxyl groups on the surface of the Al particles to form composite Al particles coated with inorganic-organic hybrid films.Compared with raw Al particles,the corrosion resistance and adhesive properties of paint films containing the composite Al particles were improved greatly,while the glossiness of the paint films decreased slightly,from 48.6° to 47.0°.In alkaline media(pH 11),the volume of evolved H_2 of composite Al particles was only 3.5 mL,whereas that of raw Al was 83.5 mL.The glossiness of paint films containing composite Al particles decreased by 1.66%after immersion in alkaline media for24 h,whereas that of raw Al decreased by 14.82%.Peel-off tests of the paint films showed that the composite particles moved slightly away from the paint films.In contrast,the raw Al particles were seriously desquamated,suggesting encapsulation of hybrid films can greatly improve the adhesive properties of Al particles in paint films. | Pihui Pi Chao Liu Xiufang Wen Lianfu Zheng Shouping Xu Jiang Cheng | 2015 | Particuology2015，13，2： | 5 |
| 2 | Struc-ture-dependent charge density as a determinant of anti- microbial activity of peptide analogues of defensin 显示文摘 | BAI Yang LIU Shouping JIANG Ping | 2009 | Biochemistry2009，48，30： | 1 |
| 3 | The Impact of Ice Phase Cloud Parameterizations on Tropical Cyclone Prediction显示文摘 | Jin Yi Wang Shouping Nachamkin Jason Doyle James D Thompson Gregory Grasso Lewis Holt Teddy Moskaitis Jon Jin Hao Hodur Richard M Zhao Qingyun Liu Ming DeMaria Mark | 2014 | Monthly Weather Review2014，，2： | 1 |
| 4 | Synthesis and surface charac terization of an amphiphilic fluorinated copolymer via emulsifier-free emulsion polymerization of RAFT 显示文摘 | Xu Shouping Liu Weiqu | 2008 | Journal of Fluorine Chemistry2008，129，2： | 1 |
| 5 | Synthesis of amphiphilic flu- orinated copolymer and the formation of hollow nano- tubes显示文摘 | Xu Shouping Liu Weiqu | 2008 | Colloids and Surfaces A: Physicochemieal and Engineering Aspects2008，326，3： | 1 |
| 6 | Calculation of diagonal section and cross-section bending capacity for strengthening RC structure using high-performance ferrocement laminate显示文摘Because there is a great demand of reinforce-ment and retrofitting of aged structures nationwide,as well as the rapid development of innovative building materials,the adoption of strengthening RC structures using new inorganic materials has become possible.High-performance ferrocement laminate(HPFL)is an effective method of strengthening concrete structure.High-performance ferrocement laminate is a new type of inorganic material with the advantages such as high strength,small contraction,good bonding properties,etc.This paper introduces the formula of cross-section bending capacity for strengthening concrete beams with HPEL.A comparative analysis of experimental data,as well as the calculation of diagonal section bearing capacity of concrete members,is given. | Shouping SHANG Fangyuan ZHOU Wei LIU | 2009 | Frontiers of Structural and Civil Engineering2009，3，3： | 1 |
| 7 | Geographic differentiation and phylogeographic relationships among world soybean populations显示文摘A fast-growing protein and oil crop,soybean was domesticated in ancient China and disseminated early in Asia and afterwards to other continents,in particular the Americas in recent centuries.After adaptation,locally developed landraces and cultivars formed a diversity of geographic-populations.In an investigation of their phylogeographic features,marker-derived traits were combined with geography-related photo-and temperaturesensitive traits to study 13 geographic-populations comprising 371 accessions.Extreme differentiation among geographic-populations was observed for flowering date(33–94 days),maturity date(79–181 days),and main stem node number(6–25 nodes).Restriction-site associated DNA sequencing revealed strong genetic differentiation among these geographic-populations,including genetic richness(alleles,35,242–44,986)and specific-present alleles(SPAs,0–67).More SPAs(28–67)emerged in some secondary and tertiary centers than in centers of origin(8–11).Phenotypic and genotypic clustering divided 11 of the 13 geographic-populations into the same five sets of sensitivity-similar geographic-populations and grouped the populations of northeast China and northern North America rather than center-of-origin populations as secondary centers,indicating the importance of geography-related traits in determining genetic differences among geographic-populations.A model of four soybean dissemination paths is presented:from the center of origin to the north,east,and south in Asia and from northeast China to Europe and the Americas.These findings provide a detailed phylogeographic understanding of worldwide soybeans. | Xueqin Liu Jianbo He Yufeng Wang Guangnan Xing Yan Li Shouping Yang Tuanjie Zhao Junyi Gai | 2020 | The Crop Journal2020，8，2： | 1 |
| 8 | Cyclooxygenase-2 inhibitor NS-398 improves survival and restores leukocyte counts in burn infection显示文摘 | Shoup M He LK Liu H | 1998 | J Trauma1998，45，2： | 1 |
| 9 | Ovarian Conservation at the Time of Hysterectomy for Benign Disease显示文摘 | WILLIAM H. PARKER MICHAEL S. BRODER ZHIMEI LIU DONNA SHOUPE CINDY FARQUHAR JONATHAN S. BEREK | 2007 | Clinical Obstetrics and Gynecology2007，，： | 1 |
| 10 | Computer simulation of three-dimensional object parallel correlation pattern recognition显示文摘 | LIU Feng | 1996 | Proc SPIE1996，2890，： | 1 |
| 11 | The deubiquitylase UCHL3 maintains cancer stem-like properties by stabilizing the aryl hydrocarbon receptor显示文摘Cancer stem cells(CSCs)exhibit highly aggressive and metastatic features and resistance to chemotherapy and radiotherapy.Aryl hydrocarbon receptor(AhR)expression varies among non-small cell lung cancers(NSCLCs),and the mechanisms that support abnormal AhR expression in CSCs remain elusive.Here,we identified ubiquitin carboxyl terminal hydrolase L3(UCHL3),a DUB enzyme in the UCH protease family,as a bona fide deubiquitylase of the AhR in NSCLC.UCHL3 was shown to interact with,deubiquitylate,and stabilize AhR in a manner dependent on its deubiquitylation activity.Moreover,we showed that UCHL3 promotes the stem-like characteristics and potent tumorigenic capacity of NSCLC cells.UCHL3 increased AhR stability and the binding of AhR to the promoter regions of the“stemness”genes ATP-binding cassette subfamily G member 2(ABCG2),KLF4,and c-Myc.Depletion of UCHL3 markedly downregulated the“stemness”genes ABCG2,KLF4,and c-Myc,leading to the loss of selfrenewal and tumorigenesis in NSCLCs.Furthermore,the UCHL3 inhibitor TCID induced AhR degradation and exhibited significantly attenuated efficacy in NSCLC cells with stem cell-like properties.Additionally,UCHL3 was shown to indicate poor prognosis in patients with lung adenocarcinoma.In general,our results reveal that the UCHL3 deubiquitylase is pivotal for AhR protein stability and a potential target for NSCLC-targeted therapy. | Lianlian Ouyang Bin Yan Yating Liu Chao Mao Min Wang Na Liu Zuli Wang Shouping Liu Ying Shi Ling Chen Xiang Wang Yan Cheng Ya Cao Desheng Xiao Lingqiang Zhang Shuang Liu Yongguang Tao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 12 | Supercontinuum fiber laser-based coherent anti-Stokes Raman scattering microscopy for label-free chemical imaging显示文摘Coherent anti-Stokes Raman scattering(CA RS)microscopy can resolve the chemical compo-nents and distribution of living biological systems in a label-firee manner and is favored in several disciplines.Current CA RS microscopes typically use bulky,high-performance solid-state lasers,which are expensive and sensitive to environmental changes.With their relatively low cost and environmental sensitivity,supercontinum fiber(SF)lasers with a small footprint have found increasing use in biomedical applications.Upon these features,in this paper,we homebuilt a low-cost CARS microscope based on a SF laser module(scCA RS microscope).This SF laser module is specially customized by adding a time synchronized seed source channel to the SF laser to form a dual-channel output laser.The performance of the scCARS microscope is evaluated with dimethyl sulfoxide,whose results confirm a spatial resolution of better than 500nm and a detection sensitivity of millimolar concentrations.The dual-color imaging capability is further demonstrated by imaging different species of mixed microspheres.We finally explore the potential of our scCARS microscope by mapping lipid droplets in different cancer cells and corneal stromal lenses. | Nan Wang Jiaojiao Zhang Wangting Zhou Siting Liu Jing Li Xinyi Xu Qi Zeng Yong Li Shouping Zhu Xueli Chen | 2022 | Journal of Innovative Optical Health Sciences2022，15，4： | 0 |
| 13 | The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties显示文摘Posttranslational modifications(PTMs)of proteins,including chromatin modifiers,play crucial roles in the dynamic alteration of various protein properties and functions including stem-cell properties.However,the roles of Lymphoid-specific helicase(LSH),a DNA methylation modifier,in modulating stem-like properties in cancer are still not clearly clarified.Therefore,exploring PTMs modulation of LSH activity will be of great significance to further understand the function and activity of LSH.Here,we demonstrate that LSH is capable to undergo PTMs,including methylation and phosphorylation.The arginine methyltransferase PRMT5 can methylate LSH at R309 residue,meanwhile,LSH could as well be phosphorylated by MAPK1 kinase at S503 residue.We further show that the accumulation of phosphorylation of LSH at S503 site exhibits downregulation of LSH methylation at R309 residue,which eventually promoting stem-like properties in lung cancer.Whereas,phosphorylation-deficient LSH S503A mutant promotes the accumulation of LSH methylation at R309 residue and attenuates stem-like properties,indicating the critical roles of LSH PTMs in modulating stem-like properties.Thus,our study highlights the importance of the crosstalk between LSH PTMs in determining its activity and function in lung cancer stem-cell maintenance. | Na Liu Rui Yang Ying Shi Ling Chen Yating Liu Zuli Wang Shouping Liu Lianlian Ouyang Haiyan Wang Weiwei Lai Chao Mao Min Wang Yan Cheng Shuang Liu Xiang Wang Hu Zhou Ya Cao Desheng Xiao Yongguang Tao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 14 | Noncoding RNAs:the shot callers in tumor immune escape显示文摘Immunotherapy,designed to exploit the functions of the host immune system against tumors,has shown considerable potential against several malignancies.However,the utility of immunotherapy is heavily limited due to the low response rate and various side effects in the clinical setting.Immune escape of tumor cells may be a critical reason for such low response rates.Noncoding RNAs(ncRNAs)have been identified as key regulatory factors in tumors and the immune system.Consequently,ncRNAs show promise as targets to improve the efficacy of immunotherapy in tumors.However,the relationship between ncRNAs and tumor immune escape(TIE)has not yet been comprehensively summarized.In this review,we provide a detailed account of the current knowledge on ncRNAs associated with TIE and their potential roles in tumor growth and survival mechanisms.This review bridges the gap between ncRNAs and TIE and broadens our understanding of their relationship,providing new insights and strategies to improve immunotherapy response rates by specifically targeting the ncRNAs involved in TIE. | Lei Liu Qin Wang Zhilin Qiu Yujuan Kang Jiena Liu Shipeng Ning Yanling Yin Da Pang Shouping Xu | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 15 | A new Chinese standard for testing of quality control in medical proton/heavy ion beam radiotherapy equipment显示文摘With the development of social economy and radiotherapy technique,proton/heavy ion radiotherapy has been applied widely to clinical practices.At present,there are at least 29 hospitals in China at various stages of planning,construction,commissioning or clinical operation of medical proton/heavy ion beam radiotherapy equipment.Compared with common radiotherapy accelerators used in conventional external beam radiotherapy,the proton/heavy ion therapy system has more stringent requirements for quality control so as to achieve an optimum therapeutic effect.In order to protect the health rights of patients undergoing radiotherapy,to facilitate the relevant administrative supervision departments to carry out standard-based approval and routine supervision and to promote the development of related medical undertakings,the standard for testing of quality control for medical proton/heavy ion beam radiotherapy equipment is drafted to fill the gap in this regard in China and even worldwide.The standard contains five indicators and corresponding testing methods for radiological protection and safety and 16 indicators for quality control of equipment performance.The standard is a mandatory standard and is based on the relevant Chinese legal requirements for the testing of radiotherapy equipment,so all the indicators listed in the standard shall be tested.During the drafting of the standard,the opinions from hospitals that are currently using proton/heavy ion medical accelerators for radiotherapy purpose and from the related equipment manufacturers were taken into account.The draft standard was revised with reference to these opinions and the feasibility of the related quality control requirements.The official version of the standard was released on March 7,2023,and implementation is scheduled to begin on March 1,2024. | Jilong Yuan Xiangjie Ma Quanfu Sun Haikuan Liu Shouping Xu Yinxiangzi Sheng Xiaoyun Ma Xiangkui Mu Xinguo Liu Tao Yang Xin Zhang Hsiao-Ming Lu Jinsheng Cheng | 2023 | Radiation Medicine and Protection2023，4，4： | 0 |
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