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您的检索式：作者名="Shuangli Mi"
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| 1 | Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function显示文摘Exosomes are 40–100 nm nano-sized vesicles that are released from many cell types into the extracellular space. Such vesicles are widely distributed in various body fluids. Recently,m RNAs and micro RNAs(mi RNAs) have been identified in exosomes, which can be taken up by neighboring or distant cells and subsequently modulate recipient cells. This suggests an active sorting mechanism of exosomal mi RNAs, since the mi RNA profiles of exosomes may differ from those of the parent cells. Exosomal mi RNAs play an important role in disease progression, and can stimulate angiogenesis and facilitate metastasis in cancers. In this review, we will introduce the origin and the trafficking of exosomes between cells, display current research on the sorting mechanism of exosomal mi RNAs, and briefly describe how exosomes and their mi RNAs function in recipient cells.Finally, we will discuss the potential applications of these mi RNA-containing vesicles in clinical settings. | Jian Zhang Sha Li Lu Li Meng Li Chongye Guo Jun Yao Shuangli Mi | 2015 | Genomics, Proteomics & Bioinformatics2015，13，1： | 162 |
| 2 | MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia显示文摘 | Shuangli Mi Jun Lu Miao Sun | 2007 | Proc Natl Acad Sci USA2007，104，19： | 1 |
| 3 | Base-excision repair and beyond—A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015显示文摘Tomas Lindahl contributed his scientific career to unveiling fundamental mechanisms of DNA decay and repair.He made several ground-breaking discoveries on genome instability,novel DNA repair activities and pathways,and disease association.The 2015 Nobel Prize in Chemistry was awarded jointly to Tomas Lindahl,Paul Modrich and Aziz Sancar for their mechanistic studies of DNA repair.Their findings | Shuangli Mi Arne Klungland Yun-Gui Yang | 2016 | Science China(Life Sciences)2016，59，1： | 0 |
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