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| 1 | 前瞻性和回顾性心电门控冠状动脉64层CT成像:影像质量和病人放射剂量的对照性研究显示文摘目的比较一组接受前瞻性心电门控64层CT冠状动脉成像病人及另一组接受回顾性心电门控64层CT冠状动脉病人的成像质量及病人放射剂量。方法本研究依从HIPAA法案并得到了机构审查委员会的批准。由于设计是回顾性研究故不需要知情同意。2位独立阅片者分别对100例病人心脏CT成像(每组各50例)的冠状动脉进行分段影像质量评分和综合评分。计算观察者间偏差。记录对应实际扫描Z轴长度的病人放射剂量,以Z轴长度为12cm的典型心脏计算标准化剂量。结果2组病例的临床特征及CT参数匹配良好。 | W.P. Shuman K.R. Branch J.M. May L.M. Mitsumori D.W. Lockhart T.J.Dubinsky 邱建星(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 129 |
| 2 | Effect of hierarchical ZSM-5zeolite crystal size on diffusion and catalytic performance of n-heptane cracking显示文摘Hierarchical ZSM-5zeolite aggregates with different sizes of nanocrystals were synthesized using different amounts of the mesoporogen 3-aminopropyl- triethoxysilane.The effect of the crystal size on the catalytic cracking of n-heptane was investigated and the Thiele modulus and effectiveness factor were used to determine the reaction rate-limiting step.The crystal size affected the textual properties of the catalysts but not the acidic properties of the catalysts.The reaction rate was first order with respect to the n-heptane concentration.Cracking over hierarchical zeolites with nanocrystal sizes larger than about 50nm took place under transition-limiting conditions,whereas the reaction over hierarchical zeolites with nanocrystal sizes of 15 or 30nm proceeded under reaction control conditions.Hierarchical ZSM-5 zeolite aggregates with smaller nanocrystals had better selectivity for light olefins which can be ascribed to the shorter diffusion path lengths and lower diffusion resistance in these catalysts. Furthermore,these catalysts had lower coking levels which can be attributed to the substantial number of mesopores which prevent the formation of coke precursors. | Shuman Xu Xiaoxiao Zhang Dangguo Cheng Fengqiu Chen Xiaohong Ren | 2018 | Frontiers of Chemical Science and Engineering2018，12，4： | 10 |
| 3 | Simulated Sensitivity of Ozone Generation to Precursors in Beijing during a High O_(3) Episode显示文摘This study uses the WRF-Chem model combined with the empirical kinetic modeling method(EKMA curve)to study the compound pollution event in Beijing that happened in 13−23 May 2017.Sensitivity tests are conducted to analyze ozone sensitivity to its precursors,and to develop emission reduction measures.The results suggest that the model can accurately simulate the compound pollution process of photochemistry and haze.When VOCs and NOx were reduced by the same proportion,the effect of O_(3)reduction at peak time was more obvious,and the effect during daytime was more significant than at night.The degree of change in ozone was peak time>daytime average.When reducing or increasing the ratio of precursors by 25%at the same time,the effect of reducing 25%VOCs on the average ozone concentration reduction was most significant.The degree of change in ozone decreased with increasing altitude,the location of the ozone maximum change shifted westward,and its range narrowed.As the altitude increases,the VOCs-limited zone decreases,VOCs sensitivity decreases,NOx sensitivity increases.The controlled area changed from near-surface VOCs-limited to high-altitude NOx-limited.Upon examining the EKMA curve,we have found that suburban and urban are sensitive to VOCs.The sensitivity tests indicate that when VOCs in suburban are reduced about 60%,the O_(3)-1h concentration could reach the standard,and when VOCs of the urban decreased by about 50%,the O_(3)-1h concentration could reach the standard.Thus,these findings could provide references for the control of compound air pollution in Beijing. | Meng CUI Xingqin AN Li XING Guohui LI Guiqian TANG Jianjun HE Xin LONG Shuman ZHAO | 2021 | Advances in Atmospheric Sciences2021，38，7： | 7 |
| 4 | High powerλ~8.5μm quantum cascade laser grown by MOCVD operating continuous-wave up to 408 K显示文摘Robust quantum cascade laser(QCL)enduring high temperature continuous-wave(CW)operation is of critical importance for some applications.We report on the realization of lattice-matched InGaAs/InAlAs/InP QCL materials grown by metal-organic chemical vapor deposition(MOCVD).High interface quality structures designed for light emission at 8.5μm are achieved by optimizing and precise controlling of growth conditions.A CW output power of 1.04 W at 288 K was obtained from a 4 mm-long and 10μm-wide coated laser.Corresponding maximum wall-plug efficiency and threshold current density were 7.1%and 1.18 kA/cm2,respectively.The device can operate in CW mode up to 408 K with an output power of 160 mW. | Teng Fei Shenqiang Zhai Jinchuan Zhang Ning Zhuo Junqi Liu Lijun Wang Shuman Liu Zhiwei Jia Kun Li Yongqiang Sun Kai Guo Fengqi Liu Zhanguo Wang | 2021 | Journal of Semiconductors2021，42，11： | 3 |
| 5 | InAs-based interband cascade lasers at 4.0 μm operating at room temperature显示文摘InAs-based interband cascade lasers(ICLs) with InAs plasmon waveguides or InAs/AlSb superlattice(SL) waveguides were demonstrated at emission wavelengths below 4.1 μm. The threshold current densities of the lasers with SL waveguides were 37 A/cm^2 at 77 K in continuous wave mode. The operation temperature of these lasers reached room temperature in pulsed mode. Compared with the thick InAs n++ plasmon cladding layer, the InAs/AlSb superlattice cladding layers have greater advantages for ICLs with wavelengths less than 4 μm even in InAs based ICLs because in the short-wavelength region they have a higher confinement factor than InAs plasmon waveguides. | Tian Yu Shuman Liu Jinchuan Zhang Bo Xu Lijun Wang Junqi Liu Ning Zhuo Shenqiang Zhai Xiaoling Ye Yonghai Chen Fengqi Liu Zhanguo Wang | 2018 | Journal of Semiconductors2018，39，11： | 3 |
| 6 | Bioassay-Guided Extraction of Crude Fucose-Containing Sulphated Polysaccharides from Sargassum fusiforme with Response Surface Methodology显示文摘The response surface methodology(RSM) combined with bioassays was employed to optimize the extraction process of crude fucose-containing sulphated polysaccharides(c FCSP) from Sargassum fusiforme. The central composite design(CCD) was used with four variables, five levels, and four responses. The four variables were p H value of hydrochloric acid solution, extraction temperature(℃), ratio of liquid to raw material(m L g^(-1)), and extraction time(h), respectively. Chemical and bioassay indices were used in combination as the response parameters, which included the yield of c FCSP, fucose content, proliferation rate of spleen cells, and lipopolysaccharide-induced proliferation of splenocytes. The experimental data were fitted to a second-order polynomial equation using multiple regression analysis, and examined using the appropriate statistical methods. The best extraction conditions were as follows: the p H value of hydrochloric acid solution was 3.50; the extraction temperature was 100℃; the ratio of liquid to raw material was 15.00 m L g^(-1) and the extraction time was 2.50 h. The experimental yield was close to the predicted from the model. The extract could promote spleen lymphocyte proliferation, especially the lipopolysaccharide-induced lymphocyte proliferation in vitro, which suggested that its immunomodulatory effect on B lymphocytes. Therefore, c FCSP extracted from S. fusiforme could be utilized as an immunostimulant in functional foods and pharmaceutical industry in future. | FU Zhifei LI Haihua LIU Hongbing HU Shuman LI Yueying WANG Mengxue GUAN Huashi | 2016 | Journal of Ocean University of China2016，15，3： | 2 |
| 7 | Electrophysiology and genetic testing in the precision medicine of congenital deafness:A review显示文摘Background:Congenital hearing loss is remarkably heterogeneous,with over 130 deafness genes and thousands of variants,making for innumerable genotype/phenotype combinations.Understanding both the pathophysiology of hearing loss and molecular site of lesion along the auditory pathway permits for significantly individualized counseling.Electrophysiologic techniques such as electrocochleography(ECochG)and electrically-evoked compound action potentials(eCAP)are being studied to localize pathology and estimate residual cochlear vs.neural health.This review describes the expanding roles of genetic and electrophysiologic evaluation in the precision medicine of congenital hearing loss.The basics of genetic mutations in hearing loss and electrophysiologic testing(ECochG and eCAP)are reviewed,and how they complement each other in the diagnostics and prognostication of hearing outcomes.Used together,these measures improve the understanding of insults to the auditory system,allowing for individualized counseling for CI candidacy/outcomes or other habilitation strategies.Conclusion:Despite tremendous discovery in deafness genes,the effects of individual genes on neural function remain poorly understood.Bridging the understanding between molecular genotype and neural and functional phenotype is paramount to interpreting genetic results in clinical practice.The future hearing healthcare provider must consolidate an ever-increasing amount of genetic and phenotypic information in the precision medicine of hearing loss. | Kevin Y.Zhan Oliver F.Adunka Adrien Eshraghi William J.Riggs Sandra M.Prentiss Denise Yan Fred F.Telischi Xuezhong Liu Shuman He | 2021 | Journal of Otology2021，16，1： | 2 |
| 8 | Comparison of gut microbiota in autism spectrum disorders and neurotypical boys in China:A case-control study显示文摘Background:Autism spectrum disorders(ASDs)are a set of complex neurobiological disorders.Growing evidence has shown that the microbiota that resides in the gut can modulate brain development via the gut–brain axis.However,direct clinical evidence of the role of the microbiota–gut–brain axis in ASD is relatively limited.Methods:A case-control study of 71 boys with ASD and 18 neurotypical controls was conducted at China-Japan Friendship Hospital.Demographic information and fecal samples were collected,and the gut microbiome was evaluated and compared by 16S ribosomal RNA gene sequencing and metagenomic sequencing.Results:A higher abundance of operational taxonomic units(OTUs)based on fecal bacterial profiling was observed in the ASD group.Significantly different microbiome profiles were observed between the two groups.At the genus level,we observed a decrease in the relative abundance of Escherichia,Shigella,Veillonella,Akkermansia,Provindencia,Dialister,Bifidobacterium,Streptococcus,Ruminococcaceae UCG_002,Megasphaera,Eubacterium_coprostanol,Citrobacter,Ruminiclostridium_5,and Ruminiclostridium_6 in the ASD cohort,while Eisenbergiella,Klebsiella,Faecalibacterium,and Blautia were significantly increased.Ten bacterial strains were selected for clinical discrimination between those with ASD and the neurotypical controls.The highest AUC value of the model was 0.947.Conclusion:Significant differences were observed in the composition of the gut microbiome between boys with ASD and neurotypical controls.These findings contribute to the knowledge of the alteration of the gut microbiome in ASD patients,which opens the possibility for early identification of this disease. | Fang Ye Xinying Gao Zhiyi Wang Shuman Cao Guangcai Liang Danni He Zhitang Lv Liming Wang Pengfei Xu Qi Zhang | 2021 | Synthetic and Systems Biotechnology2021，6，2： | 2 |
| 9 | Entrepreneuri al teams in new venture creation:a research agenda显示文摘 | Kamm J B Shuman J C Seeger J A Nurick A J | | 0，，04： | 1 |
| 10 | Comparison of Mehlich-1 and Mehlich-3 extractable soil boron with hot-water extractable boron显示文摘 | SHUMAN L M BANDEL V A DONOHUE S J | 1992 | Commun Soil Sci Plant Anal1992，23，12： | 1 |
| 11 | The stages of team venture formation : a decision-making model显示文摘 | Kamm J B Shuman J C Seeger J A and Nuriek A J | 1993 | Entrepreneurship Theory &Praetiee1993，17，2： | 1 |
| 12 | Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma 显示文摘 | Lourido S Shuman J Zhang C | 2010 | Nature2010，465，7296： | 1 |
| 13 | Compressive response of lightweight ceramic ablators: silicone impregna- ted reusable ceramic ablator, AIAA-3811-703显示文摘 | Parmenter K E Shuman K Milstein F | 2002 | J space- craft Rockets2002，39，2： | 1 |
| 14 | Fractionation method for soil microelements显示文摘 | Shuman L M | 1985 | Soil Science1985，140，： | 1 |
| 15 | Fraction method for soil microelements显示文摘 | SHUMAN L M | 1985 | Soil Sci1985，140，： | 1 |
| 16 | Sex differences in the prevalence of post-stroke depression:a systematic review显示文摘 | Poynter B Shuman M Diaz-Granados N | | 0，，： | 1 |
| 17 | Room temperature continuous wave operation of quantum cascade laser atλ~9.4μm显示文摘Continuous wave(CW) operation of long wave infrared(LWIR) quantum cascade lasers(QCLs) is achieved up to a temperature of 303 K. For room temperature CW operation, the wafer with 35 stages was processed into buried heterostructure lasers. For a 2-mm-long and 10-μm-wide laser with high-reflectivity(HR) coating on the rear facet, CW output power of 45 m W at 283 K and 9 m W at 303 K is obtained. The lasing wavelength is around 9.4 μm locating in the LWIR spectrum range. | Chuncai Hou Yue Zhao Jinchuan Zhang Shenqiang Zhai Ning Zhuo Junqi Liu Lijun Wang Shuman Liu Fengqi Liu Zhanguo Wang | 2018 | Journal of Semiconductors2018，39，3： | 1 |
| 18 | Organic waste amendments effect on zinc fractions of two soils显示文摘 | | 1999 | J Environ Qual1999，28，： | 1 |
| 19 | Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys显示文摘 | Crowe M Bresnahan J Shuman S | 1997 | Nature Med1997，3，1： | 1 |
| 20 | Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effecton primary tumor growth显示文摘 | Melnyk O Shuman MA Kim KJ | 1996 | Cancer Res1996，65，： | 1 |
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