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13篇 您的检索式:作者名="Simon Miles"
    题名 作者 年代 出处 被引量
1Insulin degludec, an ultra-longacting basal insulin, versus insulin glargine in basal-bolus treatment with mealtime insulin aspart in type 1 diabetes (BEGIN Basal-Bolus Type 1): a phase 3, randomised, open-label, treat-to-target non-inferiority trial显示文摘Simon Heller John Buse Miles Fisher Satish Garg Michel Marre Ludwig Merker Eric Renard David Russell-Jones Areti Philotheou Ann Marie Ocampo Francisco Huiling Pei Bruce Bode 2012The Lancet2012,,9825:2
2Vedolizumab for ulcerative colitis: Real world outcomes from a multicenter observational cohort of Australia and Oxford显示文摘BACKGROUND Vedolizumab(VDZ),a humanised monoclonal antibody that selectively inhibits alpha4-beta7 integrins is approved for use in adult moderate to severe ulcerative colitis(UC)patients.AIM To assess the efficacy and safety of VDZ in the real-world management of UC in a large multicenter cohort involving two countries and to identify predictors of achieving remission.METHODS A retrospective review of Australian and Oxford,United Kingdom data for UC patients.Clinical response at 3 mo,endoscopic remission at 6 mo and clinical remission at 3,6 and 12 mo were assessed.Cox regression models and Kaplan Meier curves were performed to assess the time to remission,time to failure and the covariates influencing them.Safety outcomes were recorded.RESULTS Three hundred and three UC patients from 14 centres in Australia and United Kingdom,[60%n=182,anti-TNF naïve]were included.The clinical response was 79%at 3 mo with more Australian patients achieving clinical response compared to Oxford(83%vs 70%P=0.01).Clinical remission for all patients was 56%,62%and 60%at 3,6 and 12 mo respectively.Anti-TNF naive patients were more likely to achieve remission than exposed patients at all the time points(3 mo 66%vs 40%P<0.001,6 mo 73%vs 46%P<0.001,12 mo 66%vs 51%P=0.03).More Australian patients achieved endoscopic remission at 6 mo compared to Oxford(69%vs 43%P=0.01).On multi-variate analysis,anti-TNF naïve patients were 1.8(95%CI:1.3-2.3)times more likely to achieve remission than anti-TNF exposed(P<0.001).32 patients(11%)had colectomy by 12 mo.CONCLUSION VDZ was safe and effective with 60%of UC patients achieving clinical remission at 12 mo and prior anti-TNF exposure influenced this outcome.Samba Siva Reddy Pulusu Ashish Srinivasan Krupa Krishnaprasad Daniel Cheng Jakob Begun CharlotteKeung Daniel Van Langenberg Lena Thin Tamara Mogilevski Peter De Cruz Graham Radford-Smith Emma Flanagan Sally Bell Soleiman Kashkooli Miles Sparrow Simon Ghaly Peter Bampton Elise Sawyer Susan Connor Quart-ul-ain Rizvi Jane M Andrews Gillian Mahy Paola Chivers Simon Travis Ian Craig Lawrance 2020World Journal of Gastroenterology2020,26,30:2
3Benign fibrous histiocytoma:a rare finding on bone scan staging for prostate adenocarcinoma显示文摘Simon MA Miles BJ 0,,01:1
4The Open Provenance Model core specification (v1.1)显示文摘Luc Moreau Ben Clifford Juliana Freire Joe Futrelle Yolanda Gil Paul Groth Natalia Kwasnikowska Simon Miles Paolo Missier Jim Myers Beth Plale Yogesh Simmhan Eric Stephan Jan Van den Bussche 2010Future Generation Computer Systems2010,,:1
5Provenance Model for Randomized Controlled Trials显示文摘Vasa Curcin Roxana Danger Wolfgang Kuchinke Simon Miles Adel Taweel and Christian Ohmann Springer Berlin Heidelberg0,,:1
6Provenance Model for Randomized Controlled Trials显示文摘Vasa Curcin Roxana Danger Wolfgang Kuchinke Simon Miles Adel Taweel Christian Ohmann Springer Berlin Heidelberg0,,:1
7Benign fibrous histiocytoma:a rare finding on bone scan staging for prostate adenocarcinoma显示文摘Simon MA Miles BJ 2003Urol Oncol2003,21,1:1
8Benign Fibrous Histiocytoma:a Rare Finding on Bone Scan Staging for Prostate Adenocarcinoma显示文摘Simon MA Miles BJ 2003Urol Oncol2003,21,1:1
9Benign fibrous histiocytoma: a rare finding on bone scan staging for prostate adenocarcinoma显示文摘Simon MA Miles BJ 2003Urol Oncol2003,21,1:1
10Transcatheter aortic valve intervention through the axillary artery for the treatment of severe aortic stenosis显示文摘Anita W. Asgar Michael J. Mullen Nicola Delahunty Simon W. Davies Miles Dalby Mario Petrou Andrea Kelleher Neil Moat 2009The Journal of Thoracic and Cardiovascular Surgery2009,,3:1
11Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function显示文摘Gavin I. Welsh Lorna J. Hale Vera Eremina Marie Jeansson Yoshiro Maezawa Rachel Lennon Deborah A. Pons Rachel J. Owen Simon C. Satchell Mervyn J. Miles Christopher J. Caunt Craig A. McArdle Hermann Pavenst?dt Jeremy M. Tavaré Andrew M. Herzenberg C. Ronal 2010Cell Metabolism2010,,4:1
12彩色斑斓的生活显示文摘大千世界里,五光十色、绚丽缤纷的色彩让宇宙万物充满情感,生机勃勃,并因各自具有不同的色彩彰显出个性的魅力:绿叶红花、蓝天白云,苍山碧海……红色的艳丽,绿色的生机,蓝色的沉稳,黑色的庄重,每一个颜色都有其独特的魅力。色彩作为人类五大感官中最重要的视觉感受,在我们日常生活的各个方面,无时无刻地与人们发生着密切的关系,它能够影响人们的情绪。Artiga Anette Stabel Bleu d'Argile Fatboy the Original Inga Sempé Kolormondo KEEPCUP Lorenzo Damiani Lilianna MANAHAN Mme Mina Ben Miled Moulin Roty Maija Puoskari Pipoca Roberta Licini Regis Anchuelo Simon Trabuc Ségo Durand Van Verre 伏平 范嘉苑 2016现代装饰(家居)2016,0,3:0
13为岁月镀上金色的光华显示文摘清晨的阳光爬满窗棂,清新而温暖,窗台上的花儿散发着淡淡的香气,沁人心脾。一个人的时光,你可以坐拥一杯茶的安暖,看蔚蓝的天空上白云悠悠,让一颗心在尘世浮躁中安静下来,感悟生活带给我们的点点滴滴的美好,在时光的百转干回中,品味岁月的静好。光阴茬苒,流年轻叹,每个人的心里都装着岁月的痕迹。当我们踩着岁月的台阶一步步地走向成熟,当我们睡眼惺忪地发现自己已不再年轻时。Alan Wisniewski Alvaro Goula & Pablo Figuera Cristian Mohaded David Green & Eugenie De Loynes Daevas Design Gingerlily JSPR Kateryna Sokolova Lena Billmeier & David Baur Mme Mina Ben Miled Maud Opdebeck Peter Karpf Simla Sa Simon Legald 伏平 范嘉苑 2016现代装饰(家居)2016,0,5:0
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