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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | External knowledge acquisition, creativity and learning in or- ganisational problem solving 显示文摘 | Soo C W Devinney T M Midgley D F | 2007 | International Jour- nal of Technology Management2007，38，12： | 1 |
| 3 | CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney显示文摘 | Soos T J Sims T N Barisoni L Lin K Littman D R Dustin M L | 2006 | Kidney lnt2006，70，： | 1 |
| 4 | Extending existing dependency theory to temporal databasesi显示文摘 | JENSEN C S SNODGRASS R T SOO M D | 1996 | IEEE Transactions on Knowledge and Data Engineering1996，8，4： | 1 |
| 5 | Endogenous prostaglandin D2 synthesis reduces an in- crease in plasminogen activator inhibitor-I following interleukin stimulation in bovine endothelial cells 显示文摘 | Negoro H Soo Shin W Hakamada-Taguchi R Eguchi N Urade Y Goto A Toyo-Oka T Fujita T Omata M Uehara Y | 2002 | J Hypertens2002，20，： | 1 |
| 6 | Elim inaction of Cymbidium mosaic virus and Odontoglossum ringspot virus from orchids by meristem culture and thin section culture with chemotherapy显示文摘 | Lim S T Wong S M Soo F | 1993 | Journal of Virological Methods1993，41，： | 1 |
| 7 | Extending existing dependency theory to temporal databases 显示文摘 | C S Jensen R T Snodgrass M D Soo | 1996 | IEEE Trans on Knowledge and Data Engineering1996，8，4： | 1 |
| 8 | External knowledge acquisition, creativity and learning in orga- nizational problem solving显示文摘 | Soo C W Devinney T M Midgley D F | 2007 | International Journal of Technology Management2007，38，12： | 1 |
| 9 | Design of hierarchically meso-macroporous tetragonal ZrO2 thin fihns with tunable thickness by spin-coating via sol-gel template route 显示文摘 | Soo M T Kawamura G Muto H | 2013 | Microporous and Mesoporous Materials2013，167，： | 1 |
| 10 | Detection of epidermal growth fac- tor receptor variations by partially denaturing HPLC 显示文摘 | Chin T M Anuar D Soo R | 2007 | Clin Chem2007，53，1： | 1 |
| 11 | 查看详情显示文摘 | Hiroko O Sukeo Y Tetsuo K Shigeyoshi H Toshiaki M Soo Ryan K Takeyuki M Kenzo K Toshiro T | | 0，，5： | 1 |
| 12 | Extending existing dependency theory to temporal databases 显示文摘 | Jensen C S Snodgrass R T Soo M D | 1996 | IEEE Transactions on Knowledge and Data Engineering1996，8，4： | 1 |
| 13 | Benefit Segmentation of Japanese Pleasure Travelers to the USA and Canada: Selecting Target Markets Based on the Profitability and Risk of Individual Market Segments显示文摘 | Soo C J Morrimn A M O' Leary J T | 2002 | Tourism Management2002，23，4： | 1 |
| 14 | Benefit segmentation of Japanese pleasure travelers to the USA and Canada:selecting target markets based on the profitability and risk of individual market segments显示文摘 | Soo Cheong Janga Morrisona A M OLeary J T | 2002 | Tourism Management2002，23，4： | 1 |
| 15 | Extending existing dependency theory to temporal databases显示文摘 | C S Jensen R T Snodgrass M D Soo | 1996 | IEEE Trans Knowledge and Data Engineering1996，8，4： | 1 |
| 16 | External Knowledge Acqui- sition, Creativity and laming in Organizational Problem Solving 显示文摘 | Soo C W Devinney T M Midgley D F | 2007 | International Journal of Technology Mmaagent2007，38，1： | 1 |
| 17 | Microbial community composition in soils of Northern Victoria Land,Antarctica 显示文摘 | Niederberger T D McDonald I R Hacker A L Soo R M Barrett J E Wall D H Cary S C | 2008 | Environmental Microbiology2008，10，7： | 1 |
| 18 | External Knowledge Acquisition, Creativity and Learning in Organizational Problem Solving 显示文摘 | SOO C W DEVINNEY T M MIDGLEY D F | 2007 | International Journal of Technology Management2007，38，12： | 1 |
| 19 | Benefit Segmentafion of Japanese Pleasure Travelers to the USA and Canada; Selecting Target Markets Based on the Prtfitability and Risk of Individual Market Segmetats显示文摘 | Soo Cheong Janga Morrisona A M OLeary J T | 2002 | Tourism Manegement2002，23，4： | 1 |
| 20 | External knowledge acquisition, creativity and learning in of or- ganizational problem solving显示文摘 | Soo C W Devinney T M Midgley D F | 2007 | International Journal of Technology Management2007，38，2： | 1 |
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