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| 1 | Sperm hyaluronidase is critical to mammals'fertilization for its ability to disperse cumulus-oocyte complex layer显示文摘Glycosylphosphatidylinositol-anchored sperm hyaluronidases have long been believed to assist in sperm penetration through the cumulus-oocyte complex(COC);however,their role in mammalian fertilization remains unclear.Previously,we have shown that hyaluronidase 5(Hyal5)/Hyal7 double-knockout(dKO)mice produce significantly fewer offspring than their wild-type(WT)counterparts because of defective COC dispersal.Male infertility is mainly caused by a low sperm count.It can be further exacerbated by the deficiency of sperm hyaluronidase,which disperses the cumulus cells of the outer layer of the COC.In the current study,we evaluated the effects of a low count of Hyal-deficient sperm and conditions of ovulated oocytes on the fertilization rate using a mouse model.Our results demonstrated that a low sperm count further decreases the in vitro fertilization(IVF)rate of Hyal-deficient dKO spermatozoa.In addition,the dKO spermatozoa resulted in a fertilization rate of 12.5%upon fertilizing COCs with a thick cumulus layer,whereas the IVF rate was comparable to that of WT spermatozoa when oocytes with a thin or no cumulus layer were fertilized.Finally,we proved that the IVF rate of dKO spermatozoa could be recovered by adding rat spermatozoa as a source of sperm hyal.Our results suggest that a deficiency of proteins involved in fertilization,such as sperm hyal,has a vital role in fertilization. | Dong-Won Seol Sang Hoon Joo Young-Hyun Kim Bong-Seok Song Bo-Woong Sim Sun-Uk Kim Soojin Park Gabbine Wee Ekyune Kim | 2022 | Asian Journal of Andrology2022，24，4： | 2 |
| 2 | Carbon Materials for Electrochemical Capacitors显示文摘 | Park SooJin Kim ByungJoo | 2010 | JournalofPower Sources2010，195，24： | 1 |
| 3 | Adhesion hysteresis studies of extracted poly (dimethylsiloxane) using contact mechanics 显示文摘 | Gun Young Choi Soojin Kim Abraham Ulman | 1997 | Langmuir1997，13，23： | 1 |
| 4 | Terminal repeat retrotransposon in miniature (TRIM) as DNA markers in Brassica relatives显示文摘 | SOOJIN K KIM DH LIM M H | 2007 | Molecular Genetics and Genomics2007，278，4： | 1 |
| 5 | Molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 ( CUG2 )显示文摘 | Soojin Lee Jingu Gang Sun Bok Jeon Seung Ho Choo Bogman Lee Young-Gun Kim Yang Soon Lee Jinyoung Jung Si Young Song Sang Seok Koh | 2007 | Biochemical and Biophysical Research Communications2007，，3： | 1 |
| 6 | Toll-Like Receptors in Peripheral Nerve Injury and Neuro- pathic Pain显示文摘 | Donghoon Kim Soojin Lee and Sung Joong Lee | 2009 | Current Topics in Mi- crobiology and Immunology2009，336，： | 1 |
| 7 | Real - time analysis of intrusion detection a-lerts via correlation显示文摘 | Soojin Lee Byungchun Chung Heeyoul Kim Yunho Lee ChanilPark Hyunsoo Yoon | 2006 | Computersand Security2006，，： | 1 |
| 8 | Study on building plan for enhancing the social health of public apartments显示文摘 | Yeunsook Lee Kyoungyeon Kim Soojin Lee | 2009 | Building and Environment2009，，7： | 1 |
| 9 | Influence of activation temperature on adsorption characteristics of activated carbon fiber compositions显示文摘 | Park Soojin Kim Kidong | 2001 | Carbon2001，39，： | 1 |
| 10 | Antibacterial behavior of transi tion-metals-decorated activated carbon fibers显示文摘 | Kim Byungjoo Park Soojin | | 0，，01： | 1 |
| 11 | 学术情境下社会科学研究者的个人信息管理显示文摘随着个人需要处理的信息不断增加,有效地管理信息显得至关重要。当前的研究虽然揭示了个人信息集管理策略,但是主要局限在工作场所或特殊应用中,而且重点主要关注个人信息集管理结果,而不是管理过程中的特殊活动。因此需要更多的研究调查个人信息集管理是如何实施进行的,既要关注过程也要关注结果。 | Soojin Park Kyung-Sun Kim 占南 | 2017 | 图书情报知识2017，34，6： | 1 |
| 12 | 以丝网印刷方式印刷电子监管标签的研究显示文摘在塑料薄膜上采用丝网印刷方式印刷谐振标签,已经成为低成本电子监管标签的生产方式。以印刷方式生产的谐振标签,可以方便地在印刷过程中通过改变感应器和电容器的印刷长度和尺寸来改变谐振标签的谐振频率。谐振标签的质量因子(Q)主要取决于印刷感应器的薄膜阻抗,印刷方式生产的谐振标签能够获得的最大Q值约为45。由于这种谐振标签能够用卷筒进料的塑料薄膜进行印刷,因此,各种谐振频率的电子标签都能够通过这种印刷方式进行大批量低成本生产。 | Namsoo Lim Jaeyoung Kim Soojin Lee Namyoung Kim Gyoujin Cho 陈虹 | 2009 | 中国印刷与包装研究2009，1，3： | 1 |
| 13 | Three-dimensional kagome structures in a PCL/HA-based hydrogel scaffold to lead slow BMP-2 release for effective bone regeneration显示文摘Osteoconductive function is remarkably low in bone disease in the absence of bone tissue surrounding the grafting site,or if the bone tissue is in poor condition.Thus,an effective bone graft in terms of both osteoconductivity and osteoinductivity is required for clinical therapy.Recently,the three-dimensional(3D)kagome structure has been shown to be advantageous for bone tissue regeneration due to its mechanical properties.In this study,a polycaprolactone(PCL)kagome-structure scaffold containing a hyaluronic acid(HA)-based hydrogel was fabricated using a 3D printing technique.The retention capacity of the hydrogel in the scaffold was assessed in vivo with a rat calvaria subcutaneous model for 3 weeks,and the results were compared with those obtained with conventional 3D-printed PCL grid-structure scaffolds containing HA-based hydrogel and bulk-type HA-based hydrogel.The retained hydrogel in the kagome-structure scaffold was further evaluated by in vivo imaging system analysis.To further reinforce the osteoinductivity of the kagome-structure scaffold,a PCL kagome-structure scaffold with bone morphogenetic protein-2(BMP-2)containing HA hydrogel was fabricated and implanted in a calvarial defect model of rabbits for 16 weeks.The bone regeneration characteristics were evaluated with hematoxylin and eosin(H&E),Masson’s trichrome staining,and micro-CT image analysis. | Se-Hwan Lee Kang-Gon Lee Jaeyeon Lee Yong Sang Cho Min-Soo Ghim Soojin Kim Su-Jin Heo Yongdoo Park Young-Sam Cho Bu-Kyu Lee | 2023 | Bio-Design and Manufacturing2023，6，1： | 1 |
| 14 | Cell Penetrat- ing Peptide Conjugated Bioreducible Polymer for siRNA Delivery 显示文摘 | Hye Yeong Nam Jaesung Kim Soojin Kim | 2011 | Biomaterials2011，，32： | 1 |
| 15 | Effects of dietary supplementation of bacteriophage cocktail on health status of weanling pigs in a non-sanitary environment显示文摘Background The study evaluated the effects of bacteriophage cocktail(BP)and ZnO administered during weaning time for piglets exposed to a non-sanitary environment.The bacteriophages were designed to eliminate Escherichia coli(K88,K99 and F41),Salmonella(typhimurium and enteritidis),and Clostridium perfreingens(types A and C).Forty 21-day-old crossbreed piglets were assigned to four treatments,including the PC(sanitary environment),NC(nonsanitary environment),BP(NC plus 108 pfu/kg BP),and ZO(NC plus 2,500 mg/kg ZnO).Piglets in the NC,BP and ZO were kept in a non-sanitary environment for 14 d,which was contaminated with the feces of infected pigs.Results Pigs in the BP and ZO treatments had a higher final body weight compared with the NC.The NC treatment showed the highest concentration of inflammatory cytokines including interleukin(IL)-1β,IL-6 and tumor necrosis factor-αin the plasma.The administration of BP and ZO showed lower myeloperoxidase concentrations compared with the NC.The NC treatment showed a lower concentration of superoxide dismutase in serum compared with the PC.Among the treatments in non-sanitary environment,the NC treatment showed a higher concentration of malondialdehyde compared with the ZO.The PC treatment showed a lower concentration of butyric acid in the feces compared with the BP treatment.Among non-sanitary treatments,the villus height in the duodenum was greater in the BP and ZO compared with the NC.The lower abundance of Proteobacteria phylum was observed in the BP and PC treatments compared with the NC.The highest relative abundance of Eubacterium was recorded in the BP treatment.The abundance of Megasphaera and Schwartzia was higher in the NC pigs compared with the BP piglets.The abundance of Desulfovibrio was lower in the supplemented treatments(BP and ZO)compared with non-supplemented(NC and PC).The abundance of Cellulosilyticum genera was higher in the BP and ZO treatments rather than in the NC.The piglets in the NC treatment had the highest abundance of Escherichia-Shigella,followed by the PC and ZO treatments.Conclusion In conclusion,these results suggest that the supplementation of bacteriophage cocktail could effectively control Proteobacteria phylum,Clostridium spp.and coliforms population and mitigated the adverse influences of weaning stress in piglets. | YoHan Choi Abdolreza Hosseindoust Sang Hun Ha Joeun Kim YeJin Min YongDae Jeong JunYoung Mun SooJin Sa JinSoo Kim | 2023 | Journal of Animal Science and Biotechnology2023，14，4： | 0 |
| 16 | Efficient Remote Identification for Drone Swarms显示文摘With the advancement of unmanned aerial vehicle(UAV)technology,the market for drones and the cooperation of many drones are expanding.Drone swarms move together in multiple regions to perform their tasks.A Ground Control Server(GCS)located in each region identifies drone swarmmembers to prevent unauthorized drones from trespassing.Studies on drone identification have been actively conducted,but existing studies did not consider multiple drone identification environments.Thus,developing a secure and effective identification mechanism for drone swarms is necessary.We suggested a novel approach for the remote identification of drone swarms.For an efficient identification process between the drone swarm and the GCS,each Reader drone in the region collects the identification information of the drone swarmand submits it to the GCS for verification.The proposed identification protocol reduces the verification time for a drone swarm by utilizing batch verification to verify numerous drones in a drone swarmsimultaneously.To prove the security and correctness of the proposed protocol,we conducted a formal security verification using ProVerif,an automatic cryptographic protocol verifier.We also implemented a non-flying drone swarmprototype usingmultiple Raspberry Pis to evaluate the proposed protocol’s computational overhead and effectiveness.We showed simulation results regarding various drone simulation scenarios. | Kang-Moon Seo Jane Kim Soojin Lee Jun-WooKwon Seung-Hyun Seo | 2023 | Computers, Materials & Continua2023，76，9： | 0 |
| 17 | Factors Affecting the Genetic Diagnostic Rate in Congenital Heart Disease显示文摘Background: Over 400 genes contribute to the development of congenital heart disease (CHD). Additionally,multisystemic manifestations accompanying syndromic CHD pose a higher risk of genetic diseases. This studyinvestigated the diagnostic yield of whole-exome sequencing (WES) in patients with sporadic syndromic CHDand the phenotypic factors affecting the genetic diagnostic rate. Methods: Sixty-four patients with sporadic syndromicCHD aged <18 years underwent WES between May 2018 and December 2020 in a single tertiary center,and the association between genetic testing data and extracardiac phenotypes was analyzed. Results: Extracardiacphenotypes were measured as 3.66 ± 3.05 (standard deviation, interquartile range: 2–5) items per patient. WESdetected diagnostic variants in 19 (29.7%) patients: seven (36.8%), seven (36.8%), and five (26.3%) with pathogenicvariants, likely pathogenic variants, and variants of unknown significance, respectively. Post-diagnosis surveillanceidentified the extracardiac phenotype in 54.5% (6/11) of patients. De novo variants accounted for 76.2%(15/19) of variants and autosomal dominant inheritance for 94.7% (18/19). Most diseases were ultra-rare. No significantdifferences were noted in cardiac and extracardiac phenotypes, single or combined (all P > 0.05), betweenthe groups with and without a diagnostic variant. However, patients with ≥3 extracardiac phenotypes had a significantlyhigher likelihood of having a diagnostic variant than those with ≤2 (38.3% vs. 5.9%, odds ratio = 9.93,95% confidence interval = 1.21–81.44, P = 0.013). Conclusions: The number of extracardiac phenotypes is importantin predicting the possibility of genetic diagnosis. Physicians will be able to select patients with a high probabilityof genetic diagnosis and provide appropriate genetic counseling based on the results of this study. | Jun Sung Park Go Hun Seo Yunha Choi Soojin Hwang Minji Kang Hyo-Sang Do Young-Hwue Kim Jeong Jin Yu Ellen Ai-Rhan Kim Euiseok Jung Byong Sop Lee Jae Suk Baek Beom Hee Lee | 2022 | Congenital Heart Disease2022，17，6： | 0 |
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