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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Laparoscopie versus open simple prosta tectomy an evaluation of morbidity显示文摘 | McCullough T C Heldwein F L Soon S J Galiano M Barret E Cathelineau X | 2009 | J Endourol2009，23，： | 1 |
| 3 | A machine learning approach to coreference resolution of noun phrase 显示文摘 | Soon W M Ng H T Lira D | 2001 | Computational Linguistics2001，27，4： | 1 |
| 4 | Visualization of three dimensional pore morphologies in a high-pressure die-cast Mg Al RE alloy显示文摘 | SOON G L ARUN M G | 2007 | Scrip ta Materialia2007，56，501： | 1 |
| 5 | Highly textured, magnetic Fe(1+x)S nanorods grown on silicon 显示文摘 | Soon J M Goh L Y Loh K P | 2007 | Appl Phys Lett2007，91，08： | 1 |
| 6 | Full-face treatments with the 2 790-nm erbium:YS- GG laser system 显示文摘 | Ross EV Swann M Soon S | 2009 | J Drugs Dermatol2009，8，3： | 1 |
| 7 | A machine learning approach to coreference resolution of noun phrases显示文摘 | Soon W M Ng H T Lim D C Y | 2001 | Computational Linguistics2001，27，4： | 1 |
| 8 | A novel cooling system to reduce thermally-induced errors of machine tools显示文摘 | DONMEZ M A HAHN M H SOONS J A | 2007 | CIRP Annals-Manufacturing Technology2007，56，1： | 1 |
| 9 | Aquaculture farm food safety and diseases risk assessment ( AquaFRAM ) : development of a spreadsheet tool for salmon farms 显示文摘 | Soon J M Baines R N | 2012 | Aquacult Eng2012，49，： | 1 |
| 10 | Two-dimensional windowed fourier transform for noise reduction in fringe pattern analysis显示文摘 | Qian K M Soon S H | 2005 | Optical Engineering2005，44，7： | 1 |
| 11 | TBT toxicity on the marine microalga Nannochloropsis oculata显示文摘 | Sidharthan M Young K S Woul L H Soon P K Shin H W | 2002 | Marine Pollution Bulletin2002，45，112： | 1 |
| 12 | Long-term out comes followingVATS lobectomy for non small cell bron chogenic carcinoma显示文摘 | Wallker WS Codispoti M Soon SY | 2003 | Eur J Cardiothorac Surg2003，23，3： | 1 |
| 13 | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases显示文摘 | Soon F F Ng L M Zhou X E West G M Kovach A Tan M H Suino-Powell K M He Y Xu Y Chalmers M J Brunzelle J S Zhang H Yang H Jiang H Li J Yong E L Cutler S Zhu J K Griffin P R Melcher K Xu H E | 2012 | Science2012，335，6064： | 1 |
| 14 | Non-random seed abscission, long-distance wind dispersal and plant migration rates显示文摘 | Soons M B Bullock J M | 2008 | Journal of Ecology2008，96，： | 1 |
| 15 | Molecular Mimicry Regulates ABA Signaling by SnRK2 Kinases and PP2C Phosphatases显示文摘 | Soon F F Ng L M Zhou X E West G M Kovach A Tan M H Suino-Powell KM He Y Xu Y Chalmers MJ Brunzelle JS Zhang H Yang H Jiang H Li J Yong EL Cutler S Zhu JK Griffin PR Melcher K Xu HE | 2012 | Science2012，335，6064： | 1 |
| 16 | Effects of coexisting hydrocarbons on hydrogen permeation through a palladium membrane显示文摘 | Soon H J Katsuki K Shigeharu M | 2000 | J Membr Sci2000，170，1： | 1 |
| 17 | Characterization of the Effects of Process Parameters on Macro-segregation in a High-pressure Die-casting Magnesium Alloy 显示文摘 | Soon Gi lee G R Patel A M Gokhale | 2005 | Materials characterization2005，55，： | 1 |
| 18 | Comparison of the decomposition and N and P mineralization of canola,pea and wheat residues显示文摘 | Soon Y K Arshad M A | 2002 | Biology Fertility of Soils2002，36，1： | 1 |
| 19 | A machine learning approach to co reference resolution of nounphrase 显示文摘 | SOON W M NG H T LIM C Y | 2001 | Computational Linguistics2001，27，4： | 1 |
| 20 | Long-term outcomes following VATS lobectomy for non-small cell bronchogenic carcinoma显示文摘 | Walker WS Codispoti M Soon SY | 2003 | Eur J Cardiothorac Surg2003，23，3： | 1 |
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